TIGAR contributes to ischemic tolerance induced by cerebral preconditioning through scavenging of reactive oxygen species and inhibition of apoptosis

The divergent roles of autophagy in ischemia and preconditioning

(2015) Rui Sheng et al.   ACTA PHARMACOLOGICA SINICA

Volatile anaesthetics reduce neutrophil inflammatory response by interfering with CXC receptor-2 signalling

(2015) B. Müller-Edenborn et al.   BRITISH JOURNAL OF ANAESTHESIA

Glutathione redox imbalance in brain disorders

(2015) Feng Gu et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Effect of Remote Ischemic Preconditioning on Kidney Injury Among High-Risk Patients Undergoing Cardiac Surgery

(2015) Alexander Zarbock et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Sp3/REST/HDAC1/HDAC2 Complex Represses and Sp1/HIF-1/p300 Complex Activates ncx1 Gene Transcription, in Brain Ischemia and in Ischemic Brain Preconditioning, by Epigenetic Mechanism

(2015) L. Formisano et al.   JOURNAL OF NEUROSCIENCE

Ischemia/reperfusion-induced upregulation of TIGAR in brain is mediated by SP1 and modulated by ROS and hormones involved in glucose metabolism

(2015) Meiling Sun et al.   NEUROCHEMISTRY INTERNATIONAL

Family History in Young Patients With Stroke

(2015) Vincent Thijs et al.   STROKE

Reduced Nicotinamide Adenine Dinucleotide Phosphate, a Pentose Phosphate Pathway Product, Might Be a Novel Drug Candidate for Ischemic Stroke

(2015) Mei Li et al.   STROKE

Effect of Blood Pressure Lowering in Early Ischemic Stroke

(2015) Meng Lee et al.   STROKE

p53- and p73-independent activation of TIGAR expression in vivo

(2015) P Lee et al.   Cell Death & Disease

Endogenous level of TIGAR in brain is associated with vulnerability of neurons to ischemic injury

(2015) Lijuan Cao et al.   Neuroscience Bulletin

TIGAR regulates DNA damage and repair through pentosephosphate pathway and Cdk5-ATM pathway

(2015) Hong-Pei Yu et al.   Scientific Reports

Endoplasmic reticulum chaperone GRP78 is involved in autophagy activation induced by ischemic preconditioning in neural cells

(2015) Xiang-Yang Zhang et al.   Molecular Brain

Targeting MUC1-C is synergistic with bortezomib in downregulating TIGAR and inducing ROS-mediated myeloma cell death

(2014) L. Yin et al.   BLOOD

In-vivo detection of inflammation and neurodegeneration in the chronic phase after permanent embolic stroke in rats

(2014) Maureen Walberer et al.   BRAIN RESEARCH

TIGAR Has a Dual Role in Cancer Cell Survival through Regulating Apoptosis and Autophagy

(2014) J.-M. Xie et al.   CANCER RESEARCH

Preconditioning Stimuli Induce Autophagy via Sphingosine Kinase 2 in Mouse Cortical Neurons

(2014) Rui Sheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A TIGAR-Regulated Metabolic Pathway Is Critical for Protection of Brain Ischemia

(2014) M. Li et al.   JOURNAL OF NEUROSCIENCE

A common brain network links development, aging, and vulnerability to disease

(2014) Gwenaëlle Douaud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preconditioning provides neuroprotection in models of CNS disease: Paradigms and clinical significance

(2014) R. Anne Stetler et al.   PROGRESS IN NEUROBIOLOGY

Regulation of apoptosis by Bcl-2 cysteine oxidation in human lung epithelial cells

(2013) Sudjit Luanpitpong et al.   MOLECULAR BIOLOGY OF THE CELL

Anesthetics isoflurane and desflurane differently affect mitochondrial function, learning, and memory

(2012) Yiying Zhang et al.   ANNALS OF NEUROLOGY

Autophagy regulates endoplasmic reticulum stress in ischemic preconditioning

(2012) Rui Sheng et al.   Autophagy

The Specificity Protein Factor Sp1 Mediates Transcriptional Regulation of P2X7 Receptors in the Nervous System

(2012) Paula García-Huerta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial localization of TIGAR under hypoxia stimulates HK2 and lowers ROS and cell death

(2012) E. C. Cheung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combined prostaglandin E1 and lithium exert potent neuroprotection in a rat model of cerebral ischemia

(2011) Rui Sheng et al.   ACTA PHARMACOLOGICA SINICA

SP1 plays a pivotal role for basal activity of TIGAR promoter in liver cancer cell lines

(2011) Shubiao Zou et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Sphingosine Kinase 2 Mediates Cerebral Preconditioning and Protects the Mouse Brain Against Ischemic Injury

(2011) Lai Ming Yung et al.   STROKE

Autophagy activation is associated with neuroprotection in a rat model of focal cerebral ischemic preconditioning

(2010) Rui Sheng et al.   Autophagy

Isoflurane preconditioning reduces oxygen–glucose deprivation-induced neuronal injury via B-cell lymphoma 2 protein

(2010) Mi-Sook Gwak et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

The neuroprotective mechanism of brain ischemic preconditioning

(2009) Xiao-qian Liu et al.   ACTA PHARMACOLOGICA SINICA

Modulation of intracellular ROS levels by TIGAR controls autophagy

(2009) Karim Bensaad et al.   EMBO JOURNAL

Vanadium compounds induced mitochondria permeability transition pore (PTP) opening related to oxidative stress

(2009) Yuebin Zhao et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Preconditioning and tolerance against cerebral ischaemia: from experimental strategies to clinical use

(2009) Ulrich Dirnagl et al.   LANCET NEUROLOGY

The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C–Cdh1

(2009) Angel Herrero-Mendez et al.   NATURE CELL BIOLOGY

Apoptotic Mechanisms After Cerebral Ischemia

(2009) Brad R.S. Broughton et al.   STROKE

Isoflurane preconditioning increases B-cell lymphoma-2 expression and reduces cytochrome c release from the mitochondria in the ischemic penumbra of rat brain

(2008) Liaoliao Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY