Restenosis Inhibition and Re-differentiation of TGFβ/Smad3-activated Smooth Muscle Cells by Resveratrol

A crosstalk between TGF-β/Smad3 and Wnt/β-catenin pathways promotes vascular smooth muscle cell proliferation

(2016) Daniel M. DiRenzo et al.   CELLULAR SIGNALLING

Periadventitial drug delivery for the prevention of intimal hyperplasia following open surgery

(2016) Mirnal A. Chaudhary et al.   JOURNAL OF CONTROLLED RELEASE

A successful experimental model for intimal hyperplasia prevention using a resveratrol-delivering balloon

(2016) Valerio Tolva et al.   JOURNAL OF VASCULAR SURGERY

Local CXCR4 Upregulation in the Injured Arterial Wall Contributes to Intimal Hyperplasia

(2016) Xudong Shi et al.   STEM CELLS

In-Depth Characterization and Validation of Human Urine Metabolomes Reveal Novel Metabolic Signatures of Lower Urinary Tract Symptoms

(2016) Ling Hao et al.   Scientific Reports

Relative quantification of amine-containing metabolites using isobaric N,N-dimethyl leucine (DiLeu) reagents via LC-ESI-MS/MS and CE-ESI-MS/MS

(2015) Ling Hao et al.   ANALYST

KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis

(2015) Laura S Shankman et al.   NATURE MEDICINE

BET Bromodomain Blockade Mitigates Intimal Hyperplasia in Rat Carotid Arteries

(2015) Bowen Wang et al.   EBioMedicine

Resveratrol promotes endothelial cell wound healing under laminar shear stress through an estrogen receptor-α-dependent pathway

(2014) Arif Yurdagul et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Halofuginone Stimulates Adaptive Remodeling and Preserves Re-Endothelialization in Balloon-Injured Rat Carotid Arteries

(2014) Lian-Wang Guo et al.   Circulation-Cardiovascular Interventions

A rapamycin-releasing perivascular polymeric sheath produces highly effective inhibition of intimal hyperplasia

(2014) Xiaohua Yu et al.   JOURNAL OF CONTROLLED RELEASE

A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol

(2014) Mathew Sajish et al.   NATURE

Periadventitial Application of Rapamycin-Loaded Nanoparticles Produces Sustained Inhibition of Vascular Restenosis

(2014) Xudong Shi et al.   PLoS One

High-Throughput Screening Identifies Idarubicin as a Preferential Inhibitor of Smooth Muscle versus Endothelial Cell Proliferation

(2014) Shakti A. Goel et al.   PLoS One

Resveratrol Induces Vascular Smooth Muscle Cell Differentiation through Stimulation of SirT1 and AMPK

(2014) Anne Marie Thompson et al.   PLoS One

TGF-β/Smad3 Stimulates Stem Cell/Developmental Gene Expression and Vascular Smooth Muscle Cell De-Differentiation

(2014) Xudong Shi et al.   PLoS One

Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network

(2014) Jerome C Nwachukwu et al.   eLife

Resveratrol Attenuates Oxidative Stress Induced by Balloon Injury in the Rat Carotid Artery Through Actions on the ERK1/2 and NF-Kappa B Pathway

(2013) Jing Zhang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Ten-Eleven Translocation-2 (TET2) Is a Master Regulator of Smooth Muscle Cell Plasticity

(2013) Renjing Liu et al.   CIRCULATION

PI3K/p110  inhibition selectively interferes with arterial thrombosis and neointima formation, but not re-endothelialization: potential implications for drug-eluting stent design

(2013) E. W. Holy et al.   EUROPEAN HEART JOURNAL

Epigallocatechin-3-gallate is a potent phytochemical inhibitor of intimal hyperplasia in the wire-injured carotid artery

(2013) Vicente Orozco-Sevilla et al.   JOURNAL OF VASCULAR SURGERY

Resveratrol metabolites inhibit human metastatic colon cancer cells progression and synergize with chemotherapeutic drugs to induce cell death

(2013) Virginie Aires et al.   MOLECULAR NUTRITION & FOOD RESEARCH

TGF-β and Smad3 modulate PI3K/Akt signaling pathway in vascular smooth muscle cells

(2012) Pasithorn A. Suwanabol et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mechanisms of post-intervention arterial remodelling

(2012) S. A. Goel et al.   CARDIOVASCULAR RESEARCH

Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases

(2012) Sung-Jun Park et al.   CELL

Novel nanocomposite stent coating releasing resveratrol and quercetin reduces neointimal hyperplasia and promotes re-endothelialization

(2012) James J. Kleinedler et al.   JOURNAL OF CONTROLLED RELEASE

Resveratrol and Quercetin Interact to Inhibit Neointimal Hyperplasia in Mice with a Carotid Injury

(2012) Alok R. Khandelwal et al.   JOURNAL OF NUTRITION

Population-based analysis of inpatient vascular procedures and predicting future workload and implications for training

(2012) Jeffrey Jim et al.   JOURNAL OF VASCULAR SURGERY

Epigenetic Control of Smooth Muscle Cell Differentiation and Phenotypic Switching in Vascular Development and Disease

(2011) Matthew R. Alexander et al.   Annual Review of Physiology

SDF-1α Induction in Mature Smooth Muscle Cells by Inactivation of PTEN Is a Critical Mediator of Exacerbated Injury-Induced Neointima Formation

(2011) Raphael A. Nemenoff et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Vascular Inflammation and Repair

(2011) Teruo Inoue et al.   JACC-Cardiovascular Interventions

Resveratrol and health - A comprehensive review of human clinical trials

(2011) James M. Smoliga et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Krüppel-like Factor 4 Promotes Differentiation by Transforming Growth Factor-β Receptor-mediated Smad and p38 MAPK Signaling in Vascular Smooth Muscle Cells

(2010) Hui-xuan Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resveratrol Inhibits mTOR Signaling by Promoting the Interaction between mTOR and DEPTOR

(2010) Meilian Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of neointimal formation by trans-resveratrol: Role of phosphatidyl inositol 3-kinase-dependent Nrf2 activation in heme oxygenase-1 induction

(2010) Jung Woo Kim et al.   MOLECULAR NUTRITION & FOOD RESEARCH

TGF-β through Smad3 signaling stimulates vascular smooth muscle cell proliferation and neointimal formation

(2009) Shirling Tsai et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Phosphoinositide 3-kinase is a novel target of piceatannol for inhibiting PDGF-BB-induced proliferation and migration in human aortic smooth muscle cells

(2009) Keun Hwa Choi et al.   CARDIOVASCULAR RESEARCH

Essential role of KLF5 transcription factor in cell proliferation and differentiation and its implications for human diseases

(2009) Jin-Tang Dong et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

MicroRNA-145, a Novel Smooth Muscle Cell Phenotypic Marker and Modulator, Controls Vascular Neointimal Lesion Formation

(2009) Yunhui Cheng et al.   CIRCULATION RESEARCH

Krüppel-like Factor 5 Shows Proliferation-specific Roles in Vascular Remodeling, Direct Stimulation of Cell Growth, and Inhibition of Apoptosis

(2009) Toru Suzuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resveratrol bioavailability and toxicity in humans

(2009) Charles-Henry Cottart et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Resveratrol inhibits the mTOR mitogenic signaling evoked by oxidized LDL in smooth muscle cells

(2008) Paula M. Brito et al.   ATHEROSCLEROSIS

Conditional Deletion of Krüppel-Like Factor 4 Delays Downregulation of Smooth Muscle Cell Differentiation Markers but Accelerates Neointimal Formation Following Vascular Injury

(2008) Tadashi Yoshida et al.   CIRCULATION RESEARCH

Resveratrol Inhibits Cardiac Hypertrophy via AMP-activated Protein Kinase and Akt

(2008) Anita Y. M. Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY