3D Mass Spectrometry Imaging Reveals a Very Heterogeneous Drug Distribution in Tumors

Gold nanoparticles assisted laser desorption/ionization mass spectrometry and applications: from simple molecules to intact cells

(2016) Hani Nasser Abdelhamid et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Absolute Quantitative MALDI Imaging Mass Spectrometry: A Case of Rifampicin in Liver Tissues

(2016) Chad W. Chumbley et al.   ANALYTICAL CHEMISTRY

Molecular Pharmacology of Malignant Pleural Mesothelioma: Challenges and Perspectives From Preclinical and Clinical Studies

(2016) Stefano Thellung et al.   CURRENT DRUG TARGETS

Promising in vivo efficacy of the BET bromodomain inhibitor OTX015/MK-8628 in malignant pleural mesothelioma xenografts

(2016) Ramiro Vázquez et al.   INTERNATIONAL JOURNAL OF CANCER

Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition

(2016) Aaron N Hata et al.   NATURE MEDICINE

Three-dimensional imaging MS of lipids in atherosclerotic plaques: Open-source methods for reconstruction and analysis

(2016) Nathan H. Patterson et al.   PROTEOMICS

Serial 3D Imaging Mass Spectrometry at Its Tipping Point

(2015) Andrew D. Palmer et al.   ANALYTICAL CHEMISTRY

The Contribution of Angiogenesis to the Process of Metastasis

(2015) Diane R. Bielenberg et al.   CANCER JOURNAL

Improving drug delivery to solid tumors: Priming the tumor microenvironment

(2015) Iftikhar Ali Khawar et al.   JOURNAL OF CONTROLLED RELEASE

Bevacizumab-Induced Inhibition of Angiogenesis Promotes a More Homogeneous Intratumoral Distribution of Paclitaxel, Improving the Antitumor Response

(2015) M. Cesca et al.   MOLECULAR CANCER THERAPEUTICS

The Effects of Vandetanib on Paclitaxel Tumor Distribution and Antitumor Activity in a Xenograft Model of Human Ovarian Carcinoma

(2015) Marta Cesca et al.   NEOPLASIA

Pharmacokinetics of concomitant cisplatin and paclitaxel administered by hyperthermic intraperitoneal chemotherapy to patients with peritoneal carcinomatosis from epithelial ovarian cancer

(2014) L Ansaloni et al.   BRITISH JOURNAL OF CANCER

The pharmacological point of view of resistance to therapy in tumors

(2014) Giovanna Damia et al.   CANCER TREATMENT REVIEWS

Intratumor Heterogeneity and Its Impact on Drug Distribution and Sensitivity

(2014) I Fuso Nerini et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Direct Analysis of Triacylglycerols from Crude Lipid Mixtures by Gold Nanoparticle-Assisted Laser Desorption/Ionization Mass Spectrometry

(2014) Jeongjin Son et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Approaches for the analysis of low molecular weight compounds with laser desorption/ionization techniques and mass spectrometry

(2013) Nina Bergman et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Imaging mass spectrometry: challenges in visualization of drug distribution in solid tumors

(2013) Lavinia Morosi et al.   CURRENT OPINION IN PHARMACOLOGY

Determination of Paclitaxel Distribution in Solid Tumors by Nano-Particle Assisted Laser Desorption Ionization Mass Spectrometry Imaging

(2013) Lavinia Morosi et al.   PLoS One

Imaging mass spectrometry: A new tool for pathology in a molecular age

(2013) Jeremy L. Norris et al.   Proteomics Clinical Applications

Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels

(2013) Vikash P. Chauhan et al.   Nature Communications

Exploring Three-Dimensional Matrix-Assisted Laser Desorption/Ionization Imaging Mass Spectrometry Data: Three-Dimensional Spatial Segmentation of Mouse Kidney

(2012) Dennis Trede et al.   ANALYTICAL CHEMISTRY

3D Imaging by Mass Spectrometry: A New Frontier

(2012) Erin H. Seeley et al.   ANALYTICAL CHEMISTRY

How to improve exposure of tumor cells to drugs — Promoter drugs increase tumor uptake and penetration of effector drugs

(2011) Fabrizio Marcucci et al.   ADVANCED DRUG DELIVERY REVIEWS

Method for Simultaneous Imaging of Endogenous Low Molecular Weight Metabolites in Mouse Brain Using TiO2Nanoparticles in Nanoparticle-Assisted Laser Desorption/Ionization-Imaging Mass Spectrometry

(2011) Kamlesh Shrivas et al.   ANALYTICAL CHEMISTRY

Drug and metabolite concentrations in tissues in relationship to tissue adverse findings: a review

(2011) Mario Pellegatti et al.   Expert Opinion on Drug Metabolism & Toxicology

MALDI imaging mass spectrometry of human tissue: method challenges and clinical perspectives

(2011) Erin H. Seeley et al.   TRENDS IN BIOTECHNOLOGY

MALDI imaging mass spectrometry: bridging biology and chemistry in drug development

(2011) Stephen Castellino et al.   Bioanalysis

Multimodal Mass Spectrometric Imaging of Small Molecules Reveals Distinct Spatio-Molecular Signatures in Differentially Metastatic Breast Tumor Models

(2010) E. R. Amstalden van Hove et al.   CANCER RESEARCH

Mass Spectrometric Imaging for Biomedical Tissue Analysis

(2010) Kamila Chughtai et al.   CHEMICAL REVIEWS

A concise review of mass spectrometry imaging

(2010) Erika R. Amstalden van Hove et al.   JOURNAL OF CHROMATOGRAPHY A

Imaging mass spectrometry with silver naeoparticles reveals the distribution of fatty acids in mouse retinal sections

(2010) Takahiro Hayasaka et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Three-Dimensional Vizualization of Mouse Brain by Lipid Analysis Using Ambient Ionization Mass Spectrometry

(2009) Livia S. Eberlin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Imaging mass spectrometry of proteins and peptides: 3D volume reconstruction

(2007) Malin Andersson et al.   NATURE METHODS