A rare schizophrenia risk variant of CACNA1I disrupts CaV3.3 channel activity

An autism-associated mutation in CaV1.3 channels has opposing effects on voltage- and Ca2+-dependent regulation

(2016) Worawan B. Limpitikul et al.   Scientific Reports

The Genetics of Neuropsychiatric Diseases: Looking In and Beyond the Exome

(2015) Erin L. Heinzen et al.   Annual Review of Neuroscience

CACNA1D De Novo Mutations in Autism Spectrum Disorders Activate Cav1.3 L-Type Calcium Channels

(2015) Alexandra Pinggera et al.   BIOLOGICAL PSYCHIATRY

The thalamic reticular nucleus: A functional hub for thalamocortical network dysfunction in schizophrenia and a target for drug discovery

(2015) Judith A Pratt et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Targeting voltage-gated calcium channels in neurological and psychiatric diseases

(2015) Gerald W. Zamponi   NATURE REVIEWS DRUG DISCOVERY

Genetic disruption of voltage-gated calcium channels in psychiatric and neurological disorders

(2015) Samuel Heyes et al.   PROGRESS IN NEUROBIOLOGY

Impairment of sleep-related memory consolidation in schizophrenia: relevance of sleep spindles?

(2015) Robert Göder et al.   SLEEP MEDICINE

Evaluating State Dependence and Subtype Selectivity of Calcium Channel Modulators in Automated Electrophysiology Assays

(2014) Yuri A. Kuryshev et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Sleep spindle deficits in antipsychotic-naïve early course schizophrenia and in non-psychotic first-degree relatives

(2014) Dara S. Manoach et al.   Frontiers in Human Neuroscience

Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5'TOP mRNA translation

(2014) J. Tcherkezian et al.   GENES & DEVELOPMENT

CACNA1B mutation is linked to unique myoclonus-dystonia syndrome

(2014) J. L. Groen et al.   HUMAN MOLECULAR GENETICS

Presynaptic T-Type Ca2+ Channels Modulate Dendrodendritic Mitral-Mitral and Mitral-Periglomerular Connections in Mouse Olfactory Bulb

(2014) A. Fekete et al.   JOURNAL OF NEUROSCIENCE

Functional implications of a psychiatric risk variant within CACNA1C in induced human neurons

(2014) T Yoshimizu et al.   MOLECULAR PSYCHIATRY

De novo mutations in schizophrenia implicate synaptic networks

(2014) Menachem Fromer et al.   NATURE

A polygenic burden of rare disruptive mutations in schizophrenia

(2014) Shaun M. Purcell et al.   NATURE

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

A framework for the interpretation of de novo mutation in human disease

(2014) Kaitlin E Samocha et al.   NATURE GENETICS

Rebound burst firing in the reticular thalamus is not essential for pharmacological absence seizures in mice

(2014) S. E. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Searching for missing heritability: Designing rare variant association studies

(2014) O. Zuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Laying a solid foundation for Manhattan – ‘setting the functional basis for the post-GWAS era’

(2014) Xiaoyang Zhang et al.   TRENDS IN GENETICS

A Role for Noncoding Variation in Schizophrenia

(2014) Panos Roussos et al.   Cell Reports

Spatial and Temporal Mapping of De Novo Mutations in Schizophrenia to a Fetal Prefrontal Cortical Network

(2013) Suleyman Gulsuner et al.   CELL

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

(2013)   LANCET

Surface expression and function of Cav3.2 T-type calcium channels are controlled by asparagine-linked glycosylation

(2013) Norbert Weiss et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Trafficking-deficient hERG K+ channels linked to long QT syndrome are regulated by a microtubule-dependent quality control compartment in the ER

(2011) Jennifer L. Smith et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Reduced Sleep Spindles and Spindle Coherence in Schizophrenia: Mechanisms of Impaired Memory Consolidation?

(2011) Erin J. Wamsley et al.   BIOLOGICAL PSYCHIATRY

Sleep abnormalities in schizophrenia may suggest impaired trans-thalamic cortico-cortical communication: towards a dynamic model of the illness

(2011) Zoran Vukadinovic   EUROPEAN JOURNAL OF NEUROSCIENCE

N- andO-linked glycosylation coordinate cell-surface localization of a cardiac potassium channel

(2011) Armin Akhavan   JOURNAL OF PHYSIOLOGY-LONDON

AKT Kinase Activity Is Required for Lithium to Modulate Mood-Related Behaviors in Mice

(2011) Jen Q Pan et al.   NEUROPSYCHOPHARMACOLOGY

The CaV3.3 calcium channel is the major sleep spindle pacemaker in thalamus

(2011) S. Astori et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysfunctional Thalamus-Related Networks in Schizophrenia

(2011) D. Pinault   SCHIZOPHRENIA BULLETIN

Thalamic Dysfunction in Schizophrenia Suggested by Whole-Night Deficits in Slow and Fast Spindles

(2010) Fabio Ferrarelli et al.   AMERICAN JOURNAL OF PSYCHIATRY

Low-threshold calcium channel subunit Cav3.3 is specifically localized in GABAergic neurons of rodent thalamus and cerebral cortex

(2010) Xiao-Bo Liu et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin

(2010) Tilman Schneider-Poetsch et al.   Nature Chemical Biology

Case–case genome-wide association analysis shows markers differentially associated with schizophrenia and bipolar disorder and implicates calcium channel genes

(2010) David Curtis et al.   PSYCHIATRIC GENETICS

The Thalamic Reticular Nucleus and Schizophrenia

(2010) F. Ferrarelli et al.   SCHIZOPHRENIA BULLETIN

Reduced overnight consolidation of procedural learning in chronic medicated schizophrenia is related to specific sleep stages

(2009) Dara S. Manoach et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Two Distinct Pathways for Cyclooxygenase-2 Protein Degradation

(2008) Uri R. Mbonye et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk

(2008) V Moskvina et al.   MOLECULAR PSYCHIATRY