A Critical, Nonlinear Threshold Dictates Bacterial Invasion and Initial Kinetics During Influenza

Quantifying the therapeutic requirements and potential for combination therapy to prevent bacterial coinfection during influenza

(2016) Amber M. Smith   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Differential Type I Interferon Signaling Is a Master Regulator of Susceptibility to Postinfluenza Bacterial Superinfection

(2016) Kelly M. Shepardson et al.   mBio

Influenza-induced type I interferon enhances susceptibility to gram-negative and gram-positive bacterial pneumonia in mice

(2015) Benjamin Lee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The immunology of influenza virus-associated bacterial pneumonia

(2015) Keven M Robinson et al.   CURRENT OPINION IN IMMUNOLOGY

Influenza and Bacterial Superinfection: Illuminating the Immunologic Mechanisms of Disease

(2015) Agnieszka Rynda-Apple et al.   INFECTION AND IMMUNITY

Importance of Bacterial Replication and Alveolar Macrophage-Independent Clearance Mechanisms during Early Lung Infection with Streptococcus pneumoniae

(2015) Emilie Camberlein et al.   INFECTION AND IMMUNITY

Community-Acquired Pneumonia Requiring Hospitalization among U.S. Children

(2015) Seema Jain et al.   NEW ENGLAND JOURNAL OF MEDICINE

Community-Acquired Pneumonia Requiring Hospitalization among U.S. Adults

(2015) Seema Jain et al.   NEW ENGLAND JOURNAL OF MEDICINE

Estimating Influenza Disease Burden from Population-Based Surveillance Data in the United States

(2015) Carrie Reed et al.   PLoS One

Super-infection withStaphylococcus aureusinhibits influenza virus-induced type I IFN signalling through impaired STAT1-STAT2 dimerization

(2014) Kathrin Warnking et al.   CELLULAR MICROBIOLOGY

The co-pathogenesis of influenza viruses with bacteria in the lung

(2014) Jonathan A. McCullers   NATURE REVIEWS MICROBIOLOGY

Influenza A virus-mediated priming enhances cytokine secretion by human dendritic cells infected withStreptococcus pneumoniae

(2013) Thomas Kuri et al.   CELLULAR MICROBIOLOGY

Depletion of Alveolar Macrophages during Influenza Infection Facilitates Bacterial Superinfections

(2013) H. E. Ghoneim et al.   JOURNAL OF IMMUNOLOGY

Immune Dysfunction and Bacterial Coinfections following Influenza

(2013) D. W. Metzger et al.   JOURNAL OF IMMUNOLOGY

Complications and Associated Bacterial Coinfections Among Children Hospitalized With Seasonal or Pandemic Influenza, United States, 2003–2010

(2013) Fatimah S. Dawood, Sandra S. Chaves, Alejandro Pérez, Arthur Reingold, James Meek, Monica M. Farley, Patricia Ryan, Ruth Lynfield, Craig Morin, Joan Baumbach, Nancy M. Bennett, Shelley Zansky, Ann Thomas, Mary Lou Lindegren et al.   JOURNAL OF INFECTIOUS DISEASES

Kinetics of Coinfection with Influenza A Virus and Streptococcus pneumoniae

(2013) Amber M. Smith et al.   PLoS Pathogens

Interactions between Streptococcus pneumoniae and influenza virus: a mutually beneficial relationship?

(2012) Kirsty R Short et al.   Future Microbiology

Type I Interferon Induction during Influenza Virus Infection Increases Susceptibility to Secondary Streptococcus pneumoniae Infection by Negative Regulation of    T Cells

(2012) W. Li et al.   JOURNAL OF VIROLOGY

Poly I:C Enhances Susceptibility to Secondary Pulmonary Infections by Gram-Positive Bacteria

(2012) Xiaoli Tian et al.   PLoS One

Successive influenza virus infection and Streptococcus pneumoniae stimulation alter human dendritic cell function

(2011) Yuet Wu et al.   BMC INFECTIOUS DISEASES

Synergistic stimulation of type I interferons during influenza virus coinfection promotes Streptococcus pneumoniae colonization in mice

(2011) Shigeki Nakamura et al.   JOURNAL OF CLINICAL INVESTIGATION

Impact of the 2009 Influenza Pandemic on Pneumococcal Pneumonia Hospitalizations in the United States

(2011) Daniel M. Weinberger et al.   JOURNAL OF INFECTIOUS DISEASES

Mathematical model of a three-stage innate immune response to a pneumococcal lung infection

(2011) Amber M. Smith et al.   JOURNAL OF THEORETICAL BIOLOGY

Influenza Infection Leads to Increased Susceptibility to Subsequent Bacterial Superinfection by Impairing NK Cell Responses in the Lung

(2010) Cherrie-Lee Small et al.   JOURNAL OF IMMUNOLOGY

Influenza A Inhibits Th17-Mediated Host Defense against Bacterial Pneumonia in Mice

(2010) A. Kudva et al.   JOURNAL OF IMMUNOLOGY

A Single N66S Mutation in the PB1-F2 Protein of Influenza A Virus Increases Virulence by Inhibiting the Early Interferon Response In Vivo

(2010) G. M. Conenello et al.   JOURNAL OF VIROLOGY

Critically Ill Patients With 2009 Influenza A(H1N1) in Mexico

(2009) Guillermo Domínguez-Cherit   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice

(2009) Arash Shahangian et al.   JOURNAL OF CLINICAL INVESTIGATION

Bacterial Pathogens and Death during the 1918 Influenza Pandemic

(2009) Yu-Wen Chien et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hospitalized Patients with 2009 H1N1 Influenza in the United States, April–June 2009

(2009) Seema Jain et al.   NEW ENGLAND JOURNAL OF MEDICINE

Stimulation of Lung Innate Immunity Protects against Lethal Pneumococcal Pneumonia in Mice

(2008) Cecilia G. Clement et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Sustained desensitization to bacterial Toll-like receptor ligands after resolutionof respiratory influenza infection

(2008) Arnaud Didierlaurent et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Predominant Role of Bacterial Pneumonia as a Cause of Death in Pandemic Influenza: Implications for Pandemic Influenza Preparedness

(2008) David M. Morens et al.   JOURNAL OF INFECTIOUS DISEASES

Inhibition of pulmonary antibacterial defense by interferon-γ during recovery from influenza infection

(2008) Keer Sun et al.   NATURE MEDICINE