Necrostatin-1 treatment inhibits osteocyte necroptosis and trabecular deterioration in ovariectomized rats

CaMKII is a RIP3 substrate mediating ischemia- and oxidative stress–induced myocardial necroptosis

(2016) Ting Zhang et al.   NATURE MEDICINE

The RIP1–RIP3 Complex Mediates Osteocyte Necroptosis after Ovariectomy in Rats

(2016) Hongwang Cui et al.   PLoS One

Necroptosis mediated by receptor interaction protein kinase 1 and 3 aggravates chronic kidney injury of subtotal nephrectomised rats

(2015) Yongjun Zhu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Protective effects of necrostatin-1 on glucocorticoid-induced osteoporosis in rats

(2014) Min Feng et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Necroptosis

(2014) Andreas Linkermann et al.   NEW ENGLAND JOURNAL OF MEDICINE

PINP as a biological response marker during teriparatide treatment for osteoporosis

(2014) J. H. Krege et al.   OSTEOPOROSIS INTERNATIONAL

Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase

(2012) Liming Sun et al.   CELL

Rip1 (Receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia/reperfusion injury

(2012) Andreas Linkermann et al.   KIDNEY INTERNATIONAL

TAK1 Is Essential for Osteoclast Differentiation and Is an Important Modulator of Cell Death by Apoptosis and Necroptosis

(2012) Betty Lamothe et al.   MOLECULAR AND CELLULAR BIOLOGY

Many stimuli pull the necrotic trigger, an overview

(2011) N Vanlangenakker et al.   CELL DEATH AND DIFFERENTIATION

Loss of Caspase-8 Protects Mice Against Inflammation-Related Hepatocarcinogenesis but Induces Non-Apoptotic Liver Injury

(2011) Christian Liedtke et al.   GASTROENTEROLOGY

Fenofibrate, a PPARα agonist, has renoprotective effects in mice by enhancing renal lipolysis

(2011) Yuki Tanaka et al.   KIDNEY INTERNATIONAL

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis

(2011) Claudia Günther et al.   NATURE

Daidzein Prevents the Increase in CD4+CD28null T Cells and B Lymphopoesis in Ovariectomized Mice: A Key Mechanism for Anti-Osteoclastogenic Effect

(2011) Abdul Malik Tyagi et al.   PLoS One

Integrative physiology of the aging bone: insights from animal and cellular models

(2010) Farhan A. Syed et al.   Annals of the New York Academy of Sciences

Necroptosis as an alternative form of programmed cell death

(2010) Dana E Christofferson et al.   CURRENT OPINION IN CELL BIOLOGY

Cytokines and growth factors in the regulation of bone remodeling

(2010) Gregory R. Mundy   JOURNAL OF BONE AND MINERAL RESEARCH

Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis

(2010) G. Trichonas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of the Kinases RIP1 and RIP3 in TNF-Induced Necrosis

(2010) P. Vandenabeele et al.   Science Signaling

Necrostatin-1 reverts shikonin-induced necroptosis to apoptosis

(2009) Weidong Han et al.   APOPTOSIS

Osteocyte apoptosis and control of bone resorption following ovariectomy in mice

(2009) K.B. Emerton et al.   BONE

Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

(2009) YoungSik Cho et al.   CELL

Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α

(2009) Sudan He et al.   CELL

Using biochemical markers of bone turnover in clinical practice

(2009) F. R. SINGER et al.   CLEVELAND CLINIC JOURNAL OF MEDICINE

Ultrastructural characteristics of glucocorticoid-induced osteoporosis

(2009) B. Bouvard et al.   OSTEOPOROSIS INTERNATIONAL

RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis

(2009) D.-W. Zhang et al.   SCIENCE

RIP Kinases Initiate Programmed Necrosis

(2009) L. Galluzzi et al.   Journal of Molecular Cell Biology

Renal medullary effects of transient prehypertensive treatment in young spontaneously hypertensive rats

(2008) M. Baumann et al.   Acta Physiologica

No death without life: vital functions of apoptotic effectors

(2008) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Osteocyte Apoptosis Controls Activation of Intracortical Resorption in Response to Bone Fatigue

(2008) Luis Cardoso et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Identification of RIP1 kinase as a specific cellular target of necrostatins

(2008) Alexei Degterev et al.   Nature Chemical Biology