Negative Feedback Regulation of HIV-1 by Gene Editing Strategy

Functional screening of guide RNAs targeting the regulatory and structural HIV-1 viral genome for a cure of AIDS

(2016) Chaoran Yin et al.   AIDS

Recent advances in the identification of Tat-mediated transactivation inhibitors: progressing toward a functional cure of HIV

(2016) Oriana Tabarrini et al.   Future Medicinal Chemistry

CRISPR-Cas9 Can Inhibit HIV-1 Replication but NHEJ Repair Facilitates Virus Escape

(2016) Gang Wang et al.   MOLECULAR THERAPY

Directed evolution of a recombinase that excises the provirus of most HIV-1 primary isolates with high specificity

(2016) Janet Karpinski et al.   NATURE BIOTECHNOLOGY

CRISPR/Cas9-Derived Mutations Both Inhibit HIV-1 Replication and Accelerate Viral Escape

(2016) Zhen Wang et al.   Cell Reports

Elimination of HIV-1 Genomes from Human T-lymphoid Cells by CRISPR/Cas9 Gene Editing

(2016) Rafal Kaminski et al.   Scientific Reports

Genome editing strategies: potential tools for eradicating HIV-1/AIDS

(2015) Kamel Khalili et al.   JOURNAL OF NEUROVIROLOGY

Use of the CRISPR/Cas9 system as an intracellular defense against HIV-1 infection in human cells

(2015) Hsin-Kai Liao et al.   Nature Communications

Recent developments in the search for a cure for HIV-1 infection: Targeting the latent reservoir for HIV-1

(2014) Janet D. Siliciano et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

HIV-1 Expression Within Resting CD4+ T Cells After Multiple Doses of Vorinostat

(2014) N. M. Archin et al.   JOURNAL OF INFECTIOUS DISEASES

RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection

(2014) W. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional control of HIV latency: Cellular signaling pathways, epigenetics, happenstance and the hope for a cure

(2014) Uri Mbonye et al.   VIROLOGY

CD4+T-cell depletion in HIV infection: mechanisms of immunological failure

(2013) Afam A. Okoye et al.   IMMUNOLOGICAL REVIEWS

Lost in Transcription: Molecular Mechanisms that Control HIV Latency

(2013) Ran Taube et al.   Viruses-Basel

Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirus

(2013) Hirotaka Ebina et al.   Scientific Reports

High Cleavage Efficiency of a 2A Peptide Derived from Porcine Teschovirus-1 in Human Cell Lines, Zebrafish and Mice

(2011) Jin Hee Kim et al.   PLoS One

Evidence of persistent low-level viremia in long-term HAART-suppressed, HIV-infected individuals

(2010) Hiroyu Hatano et al.   AIDS

Replication competent molecular clones of HIV-1 expressing Renilla luciferase facilitate the analysis of antibody inhibition in PBMC

(2010) Tara G. Edmonds et al.   VIROLOGY

Detecting HIV-1 integration by repetitive-sampling Alu-gag PCR

(2009) Megan K. Liszewski et al.   METHODS

Highly Sensitive Methods Based on Seminested Real-Time Reverse Transcription-PCR for Quantitation of Human Immunodeficiency Virus Type 1 Unspliced and Multiply Spliced RNA and Proviral DNA

(2008) A. O. Pasternak et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Epigenetic Silencing of Human Immunodeficiency Virus (HIV) Transcription by Formation of Restrictive Chromatin Structures at the Viral Long Terminal Repeat Drives the Progressive Entry of HIV into Latency

(2008) R. Pearson et al.   JOURNAL OF VIROLOGY