Insulin secretion impairment in Sirt6 knockout pancreatic β cells is mediated by suppression of the FoxO1-Pdx1-Glut2 pathway
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Title
Insulin secretion impairment in Sirt6 knockout pancreatic β cells is mediated by suppression of the FoxO1-Pdx1-Glut2 pathway
Authors
Keywords
-
Journal
Scientific Reports
Volume 6, Issue 1, Pages -
Publisher
Springer Nature
Online
2016-07-26
DOI
10.1038/srep30321
References
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Related references
Note: Only part of the references are listed.- Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cells
- (2015) Xiwen Xiong et al. DIABETOLOGIA
- Sirtuin1 Suppresses Osteoclastogenesis by Deacetylating FoxOs
- (2015) Ha-Neui Kim et al. MOLECULAR ENDOCRINOLOGY
- GLUT2, glucose sensing and glucose homeostasis
- (2014) Bernard Thorens DIABETOLOGIA
- Tumor suppressor p53 cooperates with SIRT6 to regulate gluconeogenesis by promoting FoxO1 nuclear exclusion
- (2014) P. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Overexpression of Sirtuin 6 Suppresses Inflammatory Responses and Bone Destruction in Mice With Collagen-Induced Arthritis
- (2013) Hwa-Suk Lee et al. ARTHRITIS AND RHEUMATISM
- MicroRNA-146b promotes adipogenesis by suppressing the SIRT1-FOXO1 cascade
- (2013) Jiyun Ahn et al. EMBO Molecular Medicine
- The Deacetylase Sirt6 Activates the Acetyltransferase GCN5 and Suppresses Hepatic Gluconeogenesis
- (2012) John E. Dominy et al. MOLECULAR CELL
- Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6
- (2011) Eriko Michishita et al. CELL CYCLE
- Glucagon-Like Peptide 1 Inhibits the Sirtuin Deacetylase SirT1 to Stimulate Pancreatic -Cell Mass Expansion
- (2011) P.-O. Bastien-Dionne et al. DIABETES
- Overexpression of FoxO1 in the Hypothalamus and Pancreas Causes Obesity and Glucose Intolerance
- (2011) Hye-Jin Kim et al. ENDOCRINOLOGY
- Human SIRT6 Promotes DNA End Resection Through CtIP Deacetylation
- (2010) Abderrahmane Kaidi et al. SCIENCE
- SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span
- (2009) Tiara L.A. Kawahara et al. CELL
- PDX1 Deficiency Causes Mitochondrial Dysfunction and Defective Insulin Secretion through TFAM Suppression
- (2009) Benoit R. Gauthier et al. Cell Metabolism
- A Novel Hypomorphic PDX1 Mutation Responsible for Permanent Neonatal Diabetes With Subclinical Exocrine Deficiency
- (2009) M. Nicolino et al. DIABETES
- Overexpression of SIRT1 Protects Pancreatic -Cells Against Cytokine Toxicity by Suppressing the Nuclear Factor- B Signaling Pathway
- (2008) J.-H. Lee et al. DIABETES
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