Understanding the structural basis of substrate recognition by Plasmodium falciparum plasmepsin V to aid in the design of potent inhibitors

Critical assessment of methods of protein structure prediction: Progress and new directions in round XI

(2016) John Moult et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Investigation of flap flexibility of β-secretase using molecular dynamic simulations

(2015) Hezekiel M. Kumalo et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Plasmodium falciparum Plasmepsin V ( Pf PMV): Insights into recombinant expression, substrate specificity and active site structure

(2015) Nonlawat Boonyalai et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Flap dynamics of plasmepsin proteases: insight into proposed parameters and molecular dynamics

(2015) Wilson Karubiu et al.   Molecular BioSystems

The I-TASSER Suite: protein structure and function prediction

(2015) Jianyi Yang et al.   NATURE METHODS

Structural basis for plasmepsin V inhibition that blocks export of malaria proteins to human erythrocytes

(2015) Anthony N Hodder et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis for plasmepsin V inhibition that blocks export of malaria proteins to human erythrocytes

(2015) Anthony N Hodder et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The zymogen of plasmepsin V from Plasmodium falciparum is enzymatically active

(2014) Huogen Xiao et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Inhibition of Plasmepsin V Activity Demonstrates Its Essential Role in Protein Export, PfEMP1 Display, and Survival of Malaria Parasites

(2014) Brad E. Sleebs et al.   PLOS BIOLOGY

Plasmodium Nesting: Remaking the Erythrocyte from the Inside Out

(2013) Justin A. Boddey et al.   Annual Review of Microbiology

Malaria

(2013) Nicholas J White et al.   LANCET

Imperfect Duplicate Insertions Type of Mutations in Plasmepsin V Modulates Binding Properties of PEXEL Motifs of Export Proteins in Indian Plasmodium vivax

(2013) Manmeet Rawat et al.   PLoS One

Structural Rationale for the Recognition of Arginine at P3 in PEXEL Motif Containing Proteins of Plasmodium falciparum by Plasmepsin V

(2012) Lalitha Guruprasad et al.   PROTEIN AND PEPTIDE LETTERS

Structural studies of vacuolar plasmepsins

(2011) Prasenjit Bhaumik et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Structure and Mechanism of the Saposin-like Domain of a Plant Aspartic Protease

(2011) Brian C. Bryksa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SwissParam: A fast force field generation tool for small organic molecules

(2011) Vincent Zoete et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Crystal structures of the free and inhibited forms of plasmepsin I (PMI) from Plasmodium falciparum

(2011) Prasenjit Bhaumik et al.   JOURNAL OF STRUCTURAL BIOLOGY

An aspartyl protease directs malaria effector proteins to the host cell

(2010) Justin A. Boddey et al.   NATURE

Plasmepsin V licenses Plasmodium proteins for export into the host erythrocyte

(2010) Ilaria Russo et al.   NATURE

Moving in and renovating: exporting proteins from Plasmodium into host erythrocytes

(2010) Daniel E. Goldberg et al.   NATURE REVIEWS MICROBIOLOGY

Plasmepsin 4-Deficient Plasmodium berghei Are Virulence Attenuated and Induce Protective Immunity against Experimental Malaria

(2009) Roberta Spaccapelo et al.   AMERICAN JOURNAL OF PATHOLOGY

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Crystal Structures of the Histo-Aspartic Protease (HAP) from Plasmodium falciparum

(2009) Prasenjit Bhaumik et al.   JOURNAL OF MOLECULAR BIOLOGY

Malaria parasite proteins that remodel the host erythrocyte

(2009) Alexander G. Maier et al.   NATURE REVIEWS MICROBIOLOGY

Artemisinin Resistance inPlasmodium falciparumMalaria

(2009) Arjen M. Dondorp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Exported Proteins Required for Virulence and Rigidity of Plasmodium falciparum-Infected Human Erythrocytes

(2008) Alexander G. Maier et al.   CELL

Malarial proteases and host cell egress: an ‘emerging’ cascade

(2008) Michael J. Blackman   CELLULAR MICROBIOLOGY

Recent highlights in antimalarial drug resistance and chemotherapy research

(2008) David A. Fidock et al.   TRENDS IN PARASITOLOGY