Structural basis for plasmepsin V inhibition that blocks export of malaria proteins to human erythrocytes

The effect of N-methylation on transition state mimetic inhibitors of the Plasmodium protease, plasmepsin V

(2015) Michelle Gazdik et al.   MedChemComm

Transition State Mimetics of the Plasmodium Export Element Are Potent Inhibitors of Plasmepsin V from P. falciparum and P. vivax

(2014) Brad E. Sleebs et al.   JOURNAL OF MEDICINAL CHEMISTRY

The zymogen of plasmepsin V from Plasmodium falciparum is enzymatically active

(2014) Huogen Xiao et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

PTEX is an essential nexus for protein export in malaria parasites

(2014) Brendan Elsworth et al.   NATURE

PTEX component HSP101 mediates export of diverse malaria effectors into host erythrocytes

(2014) Josh R. Beck et al.   NATURE

Inhibition of Plasmepsin V Activity Demonstrates Its Essential Role in Protein Export, PfEMP1 Display, and Survival of Malaria Parasites

(2014) Brad E. Sleebs et al.   PLOS BIOLOGY

How good are my data and what is the resolution?

(2013) Philip R. Evans et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Plasmodium Nesting: Remaking the Erythrocyte from the Inside Out

(2013) Justin A. Boddey et al.   Annual Review of Microbiology

Role of Plasmepsin V in Export of Diverse Protein Families from thePlasmodium falciparumExportome

(2013) Justin A. Boddey et al.   TRAFFIC

Recent Advances in Plasmepsin Medicinal Chemistry and Implications for Future Antimalarial Drug Discovery Efforts

(2012) Marvin J. Meyers et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

An introduction to data reduction: space-group determination, scaling and intensity statistics

(2011) Philip R. Evans   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The aspartic proteinase family of three Phytophthora species

(2011) John Kay et al.   BMC GENOMICS

Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design

(2011) Nicholas A. Meanwell   JOURNAL OF MEDICINAL CHEMISTRY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

An aspartyl protease directs malaria effector proteins to the host cell

(2010) Justin A. Boddey et al.   NATURE

Plasmepsin V licenses Plasmodium proteins for export into the host erythrocyte

(2010) Ilaria Russo et al.   NATURE

N-terminal processing of proteins exported by malaria parasites

(2008) Henry H. Chang et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Role of thePlasmodiumExport Element in Trafficking Parasite Proteins to the Infected Erythrocyte

(2008) Justin A Boddey et al.   TRAFFIC