Generation of biallelic knock-out sheep via gene-editing and somatic cell nuclear transfer

Generation of B Cell-Deficient Pigs by Highly Efficient CRISPR/Cas9-Mediated Gene Targeting

(2015) Fengjiao Chen et al.   Journal of Genetics and Genomics

Efficient Generation of Myostatin Knock-Out Sheep Using CRISPR/Cas9 Technology and Microinjection into Zygotes

(2015) M. Crispo et al.   PLoS One

Targeted mutations in myostatin by zinc-finger nucleases result in double-muscled phenotype in Meishan pigs

(2015) Lili Qian et al.   Scientific Reports

FOXL2 Is a Female Sex-Determining Gene in the Goat

(2014) Laurent Boulanger et al.   CURRENT BIOLOGY

Myostatin knockout using zinc-finger nucleases promotes proliferation of ovine primary satellite cells in vitro

(2014) Fatemeh Salabi et al.   JOURNAL OF BIOTECHNOLOGY

TALEN-Mediated Modification of the Bovine Genome for Large-Scale Production of Human Serum Albumin

(2014) Shaida Moghaddassi et al.   PLoS One

Efficient Gene Knockout in Goats Using CRISPR/Cas9 System

(2014) Wei Ni et al.   PLoS One

The sheep genome illuminates biology of the rumen and lipid metabolism

(2014) Y. Jiang et al.   SCIENCE

Genome edited sheep and cattle

(2014) Chris Proudfoot et al.   TRANSGENIC RESEARCH

TALENoffer: genome-wide TALEN off-target prediction

(2013) Jan Grau et al.   BIOINFORMATICS

Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases

(2013) Y. H. Sung et al.   GENOME RESEARCH

Myostatin/activin pathway antagonism: Molecular basis and therapeutic potential

(2013) H.Q. Han et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Targeted disruption of the sheep MSTN gene by engineered zinc-finger nucleases

(2013) Cunfang Zhang et al.   MOLECULAR BIOLOGY REPORTS

Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR-Cas systems

(2013) Wei Li et al.   NATURE BIOTECHNOLOGY

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Knockdown of Myostatin Expression by RNAi Enhances Muscle Growth in Transgenic Sheep

(2013) Shengwei Hu et al.   PLoS One

Comparison of the Efficiency of Banna Miniature Inbred Pig Somatic Cell Nuclear Transfer among Different Donor Cells

(2013) Hongjiang Wei et al.   PLoS One

Site Specific Mutation of the Zic2 Locus by Microinjection of TALEN mRNA in Mouse CD1, C3H and C57BL/6J Oocytes

(2013) Benjamin Davies et al.   PLoS One

Characterization and Comparative Analyses of Muscle Transcriptomes in Dorper and Small-Tailed Han Sheep Using RNA-Seq Technique

(2013) Chunlan Zhang et al.   PLoS One

Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system

(2013) Li-En Jao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myostatin Inhibition Prevents Diabetes and Hyperphagia in a Mouse Model of Lipodystrophy

(2012) T. Guo et al.   DIABETES

Down-Regulation of Myogenin Can Reverse Terminal Muscle Cell Differentiation

(2012) Nikolaos P. Mastroyiannopoulos et al.   PLoS One

Myostatin inhibits brown adipocyte differentiation via regulation of Smad3-mediated β-catenin stabilization

(2011) Won Kon Kim et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Expression and Function of Myostatin in Obesity, Diabetes, and Exercise Adaptation

(2011) DAVID L. ALLEN et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Heritable gene targeting in zebrafish using customized TALENs

(2011) Peng Huang et al.   NATURE BIOTECHNOLOGY

TALEs of genome targeting

(2011) Jens Boch   NATURE BIOTECHNOLOGY

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

(2011) Tomas Cermak et al.   NUCLEIC ACIDS RESEARCH

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Myostatin regulates fiber-type composition of skeletal muscle by regulating MEF2 and MyoD gene expression

(2009) Alex Hennebry et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Smad2 and 3 transcription factors control muscle mass in adulthood

(2009) Roberta Sartori et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors

(2008) A. M. Haidet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA