An Artificial Reaction Promoter Modulates Mitochondrial Functions via Chemically Promoting Protein Acetylation

Mitochondrial SIRT3 Mediates Adaptive Responses of Neurons to Exercise and Metabolic and Excitatory Challenges

(2016) Aiwu Cheng et al.   Cell Metabolism

Mechanisms and Dynamics of Protein Acetylation in Mitochondria

(2016) Josue Baeza et al.   TRENDS IN BIOCHEMICAL SCIENCES

Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy

(2016) Angela V. Hafner et al.   Aging-US

Site-Specific Reactivity of Nonenzymatic Lysine Acetylation

(2015) Josue Baeza et al.   ACS Chemical Biology

Mitochondrial complex I defect and increased fatty acid oxidation enhance protein lysine acetylation in the diabetic heart

(2015) Edwin J. Vazquez et al.   CARDIOVASCULAR RESEARCH

Mitochondrial Sirt3 Expression is Decreased in APP/PS1 Double Transgenic Mouse Model of Alzheimer’s Disease

(2015) Wenxiu Yang et al.   NEUROCHEMICAL RESEARCH

Finding the Right (Bioorthogonal) Chemistry

(2014) David M. Patterson et al.   ACS Chemical Biology

SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells

(2014) Ozkan Ozden et al.   FREE RADICAL BIOLOGY AND MEDICINE

Small-molecule inhibitors at the PSD-95/nNOS interface attenuate MPP+-induced neuronal injury through Sirt3 mediated inhibition of mitochondrial dysfunction

(2014) Wei Hu et al.   NEUROCHEMISTRY INTERNATIONAL

Pre-diabetes alters testicular PGC1-α/SIRT3 axis modulating mitochondrial bioenergetics and oxidative stress

(2013) Luís Rato et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Lysine deacetylases and mitochondrial dynamics in neurodegeneration

(2013) Pedro Guedes-Dias et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Intracellular activation of acetyl-CoA by an artificial reaction promoter and its fluorescent detection

(2013) Hirokazu Komatsu et al.   CHEMICAL COMMUNICATIONS

SIRT3 deacetylates FOXO3 to protect mitochondria against oxidative damage

(2013) Anne H.H. Tseng et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Protein Deacetylase SIRT3 Prevents Oxidative Stress-induced Keratinocyte Differentiation

(2013) Alexandra S. Bause et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Widespread and Enzyme-independentNϵ-Acetylation andNϵ-Succinylation of Proteins in the Chemical Conditions of the Mitochondrial Matrix

(2013) Gregory R. Wagner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Restricted mitochondrial protein acetylation initiates mitochondrial autophagy

(2013) B. R. Webster et al.   JOURNAL OF CELL SCIENCE

The novel mutation p.Asp251Asn in the β-subunit of succinate-CoA ligase causes encephalomyopathy and elevated succinylcarnitine

(2013) Elham Jaberi et al.   JOURNAL OF HUMAN GENETICS

SIRT3 Deacetylates and Activates OPA1 To Regulate Mitochondrial Dynamics during Stress

(2013) Sadhana A. Samant et al.   MOLECULAR AND CELLULAR BIOLOGY

Chemical reporters for biological discovery

(2013) Markus Grammel et al.   Nature Chemical Biology

Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways

(2013) M. J. Rardin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An acetylome peptide microarray reveals specificities and deacetylation substrates for all human sirtuin isoforms

(2013) David Rauh et al.   Nature Communications

Identification of a molecular component of the mitochondrial acetyltransferase programme: a novel role for GCN5L1

(2012) Iain Scott et al.   BIOCHEMICAL JOURNAL

Regulation of mitochondrial FoF1ATPase activity by Sirt3-catalyzed deacetylation and its deficiency in human cells harboring 4977bp deletion of mitochondrial DNA

(2012) Yu-Ting Wu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondrial Protein Acylation and Intermediary Metabolism: Regulation by Sirtuins and Implications for Metabolic Disease

(2012) John C. Newman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SIRT3 Protein Deacetylates Isocitrate Dehydrogenase 2 (IDH2) and Regulates Mitochondrial Redox Status

(2012) Wei Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial Acetylome Analysis in a Mouse Model of Alcohol-Induced Liver Injury Utilizing SIRT3 Knockout Mice

(2012) Kristofer S. Fritz et al.   JOURNAL OF PROTEOME RESEARCH

Calorie Restriction and SIRT3 Trigger Global Reprogramming of the Mitochondrial Protein Acetylome

(2012) Alexander S. Hebert et al.   MOLECULAR CELL

Inactivation of MARCH5 Prevents Mitochondrial Fragmentation and Interferes with Cell Death in a Neuronal Cell Model

(2012) Lei Fang et al.   PLoS One

SIRT3 Deficiency and Mitochondrial Protein Hyperacetylation Accelerate the Development of the Metabolic Syndrome

(2011) Matthew D. Hirschey et al.   MOLECULAR CELL

Palladium-mediated intracellular chemistry

(2011) Rahimi M. Yusop et al.   Nature Chemistry

Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction

(2010) Shinichi Someya et al.   CELL

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

(2010) Matthew D. Hirschey et al.   NATURE

p53-Induced Growth Arrest Is Regulated by the Mitochondrial SirT3 Deacetylase

(2010) SiDe Li et al.   PLoS One

Regulation of Succinate Dehydrogenase Activity by SIRT3 in Mammalian Mitochondria

(2009) Huseyin Cimen et al.   BIOCHEMISTRY

Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes

(2009) Lei Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Visualization of ATP levels inside single living cells with fluorescence resonance energy transfer-based genetically encoded indicators

(2009) H. Imamura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

(2008) B.-H. Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA