Stochastic expression of a multiple antibiotic resistance activator confers transient resistance in single cells

Control of MarRAB Operon in Escherichia coli via Autoactivation and Autorepression

(2015) Mahendra Kumar Prajapat et al.   BIOPHYSICAL JOURNAL

Noise and Low-Level Dynamics Can Coordinate Multicomponent Bet Hedging Mechanisms

(2015) Javier Garcia-Bernardo et al.   BIOPHYSICAL JOURNAL

Obg controls bacterial persistence

(2015) Denise Waldron   NATURE REVIEWS MICROBIOLOGY

Quantifying Selective Pressures Driving Bacterial Evolution Using Lineage Analysis

(2015) Guillaume Lambert et al.   Physical Review X

Understanding the basis of antibiotic resistance: a platform for drug discovery

(2014) L. J. V. Piddock   MICROBIOLOGY-SGM

Optimization of lag time underlies antibiotic tolerance in evolved bacterial populations

(2014) Ofer Fridman et al.   NATURE

Emergence of antibiotic resistance from multinucleated bacterial filaments

(2014) Julia Bos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heteroresistance at the Single-Cell Level: Adapting to Antibiotic Stress through a Population-Based Strategy and Growth-Controlled Interphenotypic Coordination

(2014) X. Wang et al.   mBio

Reduced Drug Uptake in Phenotypically Resistant Nutrient-Starved Nonreplicating Mycobacterium tuberculosis

(2013) Jansy Sarathy et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

RETRACTED: (p)ppGpp Controls Bacterial Persistence by Stochastic Induction of Toxin-Antitoxin Activity

(2013) Etienne Maisonneuve et al.   CELL

The 216-bpmarBgene of themarRABoperon inEscherichia coliencodes a periplasmic protein which reduces the transcription rate ofmarA

(2013) Laura Vinué et al.   FEMS MICROBIOLOGY LETTERS

Contribution of phenotypic heterogeneity to adaptive antibiotic resistance

(2013) M. A. Sanchez-Romero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic Persistence of Antibiotic-Stressed Mycobacteria

(2013) Y. Wakamoto et al.   SCIENCE

Tunable Stochastic Pulsing in the Escherichia coli Multiple Antibiotic Resistance Network from Interlinked Positive and Negative Feedback Loops

(2013) Javier Garcia-Bernardo et al.   PLoS Computational Biology

Trade-offs between drug toxicity and benefit in the multi-antibiotic resistance system underlie optimal growth of E. coli

(2012) Kevin B Wood et al.   BMC Systems Biology

Transcriptional Cross Talk within themar-sox-robRegulon in Escherichia coli Is Limited to therobandmarRABOperons

(2012) Lon M. Chubiz et al.   JOURNAL OF BACTERIOLOGY

Pre-Disposition and Epigenetics Govern Variation in Bacterial Survival upon Stress

(2012) Ming Ni et al.   PLoS Genetics

Dynamics of Antibiotic Resistant Mycobacterium tuberculosis during Long-Term Infection and Antibiotic Treatment

(2011) Solomon H. Mariam et al.   PLoS One

Stochastic Pulse Regulation in Bacterial Stress Response

(2011) J. C. W. Locke et al.   SCIENCE

Asymmetry and Aging of Mycobacterial Cells Lead to Variable Growth and Antibiotic Susceptibility

(2011) B. B. Aldridge et al.   SCIENCE

Many Chromosomal Genes Modulate MarA-Mediated Multidrug Resistance in Escherichia coli

(2010) C. Ruiz et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Emergence of Pseudomonas aeruginosa Strains Producing High Levels of Persister Cells in Patients with Cystic Fibrosis

(2010) L. R. Mulcahy et al.   JOURNAL OF BACTERIOLOGY

Functional roles for noise in genetic circuits

(2010) Avigdor Eldar et al.   NATURE

Regulation of phenotypic variability by a threshold-based mechanism underlies bacterial persistence

(2010) Eitan Rotem et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multidrug Resistance in Bacteria

(2009) Hiroshi Nikaido   Annual Review of Biochemistry

Single-Molecule Approaches to Stochastic Gene Expression

(2009) Arjun Raj et al.   Annual Review of Biophysics

A chance at survival: gene expression noise and phenotypic diversification strategies

(2009) Dawn Fraser et al.   MOLECULAR MICROBIOLOGY

Model of Transcriptional Activation by MarA in Escherichia coli

(2009) Michael E. Wall et al.   PLoS Computational Biology

Activation of the Escherichia coli marA/soxS/rob Regulon in Response to Transcriptional Activator Concentration

(2008) Robert G. Martin et al.   JOURNAL OF MOLECULAR BIOLOGY