GSK-3β downregulates Nrf2 in cultured cortical neurons and in a rat model of cerebral ischemia-reperfusion

Promotion of dentin regeneration via CCN3 modulation on Notch and BMP signaling pathways

(2014) Xuefei Wang et al.   BIOMATERIALS

Antisense oligonucleotide against GSK-3β in brain of SAMP8 mice improves learning and memory and decreases oxidative stress: Involvement of transcription factor Nrf2 and implications for Alzheimer disease

(2013) Susan A. Farr et al.   FREE RADICAL BIOLOGY AND MEDICINE

Puerarin alleviates cognitive impairment and oxidative stress in APP/PS1 transgenic mice

(2013) Yanyan Zhou et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity

(2012) S Chowdhry et al.   ONCOGENE

Neuroprotection of Tanshinone IIA against Cerebral Ischemia/Reperfusion Injury through Inhibition of Macrophage Migration Inhibitory Factor in Rats

(2012) Yanlin Chen et al.   PLoS One

Sulforaphane protects primary cultures of cortical neurons against injury induced by oxygen-glucose deprivation/reoxygenation via antiapoptosis

(2012) Xuemei Wu et al.   Neuroscience Bulletin

Signaling pathways activated by the phytochemical nordihydroguaiaretic acid contribute to a Keap1-independent regulation of Nrf2 stability: Role of glycogen synthase kinase-3

(2011) Ana I. Rojo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Src Subfamily Kinases Regulate Nuclear Export and Degradation of Transcription Factor Nrf2 to Switch Off Nrf2-mediated Antioxidant Activation of Cytoprotective Gene Expression

(2011) Suryakant K. Niture et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SCF/ -TrCP Promotes Glycogen Synthase Kinase 3-Dependent Degradation of the Nrf2 Transcription Factor in a Keap1-Independent Manner

(2011) P. Rada et al.   MOLECULAR AND CELLULAR BIOLOGY

Icariside II Enhances Nrf2 Nuclear Translocation to Upregulate Phase II Detoxifying Enzyme Expression Coupled with the ERK, Akt and JNK Signaling Pathways

(2011) Jing Gu et al.   MOLECULES

Apocynum venetum leaf extract protects rat cortical neurons from injury induced by oxygen and glucose deprivation in vitro

(2010) Jun Xiang et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Tyrosine phosphorylation controls nuclear export of Fyn, allowing Nrf2 activation of cytoprotective gene expression

(2010) James W. Kaspar et al.   FASEB JOURNAL

Neuroprotective effect of 4-hydroxybenzyl alcohol against transient focal cerebral ischemia via anti-apoptosis in rats

(2009) Shan-Shan Yu et al.   BRAIN RESEARCH

Role of Glycogen Synthase Kinase-3β in Cardioprotection

(2009) Magdalena Juhaszova et al.   CIRCULATION RESEARCH

Ginsenoside Rb1 protects against 6-hydroxydopamine-induced oxidative stress by increasing heme oxygenase-1 expression through an estrogen receptor-related PI3K/Akt/Nrf2-dependent pathway in human dopaminergic cells

(2009) Yong Pil Hwang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Delayed cardioprotection afforded by the glycogen synthase kinase 3 inhibitor SB-216763 occurs via a KATP- and MPTP-dependent mechanism at reperfusion

(2008) Eric R. Gross et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The Nrf2/ARE Pathway as a Potential Therapeutic Target in Neurodegenerative Disease

(2008) Marcus J. Calkins et al.   ANTIOXIDANTS & REDOX SIGNALING

Sulforaphane protects astrocytes against oxidative stress and delayed death caused by oxygen and glucose deprivation

(2008) Camelia A. Danilov et al.   GLIA

GSK-3β down-regulates the transcription factor Nrf2 after oxidant damage: relevance to exposure of neuronal cells to oxidative stress

(2008) Ana I. Rojo et al.   JOURNAL OF NEUROCHEMISTRY

Mechanisms of ischemic brain damage

(2008) Kristian P. Doyle et al.   NEUROPHARMACOLOGY