Interplay of histidine residues of the Alzheimer’s disease Aβ peptide governs its Zn-induced oligomerization

The Metal Theory of Alzheimer's Disease

(2018) Ashley I. Bush   JOURNAL OF ALZHEIMERS DISEASE

Zinc-induced heterodimer formation between metal-binding domains of intact and naturally modified amyloid-beta species: implication to amyloid seeding in Alzheimer’s disease?

(2016) Yuri V. Mezentsev et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Solution NMR Studies of Recombinant Aβ(1-42): From the Presence of a Micellar Entity to Residual β-Sheet Structure in the Soluble Species

(2015) Marielle Aulikki Wälti et al.   CHEMBIOCHEM

Amyloid β Protein and Alzheimer’s Disease: When Computer Simulations Complement Experimental Studies

(2015) Jessica Nasica-Labouze et al.   CHEMICAL REVIEWS

Successive Stages of Amyloid-β Self-Assembly Characterized by Solid-State Nuclear Magnetic Resonance with Dynamic Nuclear Polarization

(2015) Alexey Potapov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

High Resolution Structural Characterization of Aβ42 Amyloid Fibrils by Magic Angle Spinning NMR

(2015) Michael T. Colvin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The English (H6R) familial Alzheimer's disease mutation facilitates zinc-induced dimerization of the amyloid-β metal-binding domain

(2015) S. A. Kozin et al.   Metallomics

Three dimensions of the amyloid hypothesis: time, space and 'wingmen'

(2015) Erik S Musiek et al.   NATURE NEUROSCIENCE

Metal Ions and Intrinsically Disordered Proteins and Peptides: From Cu/Zn Amyloid-β to General Principles

(2014) Peter Faller et al.   ACCOUNTS OF CHEMICAL RESEARCH

Phosphorylation of Ser8 promotes zinc-induced dimerization of the amyloid-β metal-binding domain

(2014) Alexandra A. Kulikova et al.   Molecular BioSystems

Biometals and Their Therapeutic Implications in Alzheimer’s Disease

(2014) Scott Ayton et al.   Neurotherapeutics

The role of zinc in the stability of the marginally stable IscU scaffold protein

(2014) Clara Iannuzzi et al.   PROTEIN SCIENCE

Truncated and modified amyloid-beta species

(2014) Markus P Kummer et al.   Alzheimers Research & Therapy

Self-propagation of pathogenic protein aggregates in neurodegenerative diseases

(2013) Mathias Jucker et al.   NATURE

Peripherally Applied Synthetic Peptide isoAsp7-Aβ(1-42) Triggers Cerebral β-Amyloidosis

(2013) S. A. Kozin et al.   NEUROTOXICITY RESEARCH

Structural studies of the tethered N-terminus of the Alzheimer's disease amyloid-β peptide

(2013) Rebecca M. Nisbet et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Biochemistry of Amyloid  -Protein and Amyloid Deposits in Alzheimer Disease

(2013) C. L. Masters et al.   Cold Spring Harbor Perspectives in Medicine

NMR Solution Structure of Rat Aβ(1–16): Toward Understanding the Mechanism of Rats' Resistance to Alzheimer's Disease

(2012) Andrey N. Istrate et al.   BIOPHYSICAL JOURNAL

The Amyloid Beta Peptide: A Chemist’s Perspective. Role in Alzheimer’s and Fibrillization

(2012) I. W. Hamley   CHEMICAL REVIEWS

Metal binding sites in amyloid oligomers: Complexes and mechanisms

(2012) Yifat Miller et al.   COORDINATION CHEMISTRY REVIEWS

Purified and synthetic Alzheimer's amyloid beta (A ) prions

(2012) J. Stohr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamics of ZnII Binding as a Key Feature in the Formation of Amyloid Fibrils by Aβ11-28

(2011) Bruno Alies et al.   INORGANIC CHEMISTRY

A New Structural Model of Aβ40Fibrils

(2011) Ivano Bertini et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Alzheimer's disease

(2011) Clive Ballard et al.   LANCET

Zinc-induced dimerization of the amyloid-β metal-binding domain 1–16 is mediated by residues 11–14

(2011) Sergey A. Kozin et al.   Molecular BioSystems

Minimal Zn 2+ Binding Site of Amyloid- β

(2010) Philipp O. Tsvetkov et al.   BIOPHYSICAL JOURNAL

Effects of the English (H6R) and Tottori (D7N) Familial Alzheimer Disease Mutations on Amyloid β-Protein Assembly and Toxicity

(2010) Kenjiro Ono et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modeling the Cu+Binding in the 1−16 Region of the Amyloid-β Peptide Involved in Alzheimer’s Disease

(2010) Sara Furlan et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Optimization of the methods for small peptide solution structure determination by NMR spectroscopy

(2010) A. N. Istrate et al.   MOLECULAR BIOLOGY

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Zinc ions promote Alzheimer A  aggregation via population shift of polymorphic states

(2010) Y. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Improved side-chain torsion potentials for the Amber ff99SB protein force field

(2010) Kresten Lindorff-Larsen et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Amphiphilic peptides and their cross-disciplinary role as building blocks for nanoscience

(2009) Silvia Cavalli et al.   CHEMICAL SOCIETY REVIEWS

A Role for Synaptic Zinc in Activity-Dependent A  Oligomer Formation and Accumulation at Excitatory Synapses

(2009) A. Deshpande et al.   JOURNAL OF NEUROSCIENCE

A novel pathway for amyloid precursor protein processing

(2009) Erik Portelius et al.   NEUROBIOLOGY OF AGING

A Recessive Mutation in the APP Gene with Dominant-Negative Effect on Amyloidogenesis

(2009) G. Di Fede et al.   SCIENCE

Isomerization of the Asp7 Residue Results in Zinc‐Induced Oligomerization of Alzheimer’s Disease Amyloid β(1–16) Peptide

(2008) Philipp O. Tsvetkov et al.   CHEMBIOCHEM

Bioinorganic chemistry of copper and zinc ions coordinated to amyloid-β peptide

(2008) Peter Faller et al.   DALTON TRANSACTIONS

p3 peptide, a truncated form of Aβ devoid of synaptotoxic effect, does not assemble into soluble oligomers

(2008) Fabienne Dulin et al.   FEBS LETTERS

Mechanism of zinc(II)-promoted amyloid formation: zinc(II) binding facilitates the transition from the partially α-helical conformer to aggregates of amyloid β protein(1–28)

(2008) Christine Talmard et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Platinum-based inhibitors of amyloid-  as therapeutic agents for Alzheimer's disease

(2008) K. J. Barnham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA