Deletion of Galectin-3 Enhances Xenobiotic Induced Murine Primary Biliary Cholangitis by Facilitating Apoptosis of BECs and Release of Autoantigens

Ustekinumab for patients with primary biliary cholangitis who have an inadequate response to ursodeoxycholic acid: A proof-of-concept study

(2016) Gideon M. Hirschfield et al.   HEPATOLOGY

AAV-IL-22 modifies liver chemokine activity and ameliorates portal inflammation in murine autoimmune cholangitis

(2016) Yu-Hsin Hsueh et al.   JOURNAL OF AUTOIMMUNITY

Immunological potential of cytotoxic T lymphocyte antigen 4 immunoglobulin in murine autoimmune cholangitis

(2015) H. Tanaka et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Animal Models of Primary Biliary Cirrhosis

(2015) Tomohiro Katsumi et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Unmet Challenges in Immune-Mediated Hepatobiliary Diseases

(2015) Ulrich Beuers et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Galectin-3 in autoimmunity and autoimmune diseases

(2015) Felipe L de Oliveira et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Chemokine (C-X-C motif) ligand 13 promotes intrahepatic chemokine (C-X-C motif) receptor 5+ lymphocyte homing and aberrant B-cell immune responses in primary biliary cirrhosis

(2015) Yongyin Li et al.   HEPATOLOGY

Natural killer cells regulate T cell immune responses in primary biliary cirrhosis

(2015) Shinji Shimoda et al.   HEPATOLOGY

CXCR5+CD4+T follicular helper cells participate in the pathogenesis of primary biliary cirrhosis

(2015) Lifeng Wang et al.   HEPATOLOGY

Systems biologic analysis of T regulatory cells genetic pathways in murine primary biliary cirrhosis

(2015) Yin-Hu Wang et al.   JOURNAL OF AUTOIMMUNITY

Genetics in PBC: What Do the “Risk Genes” Teach Us?

(2014) Gideon M. Hirschfield et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Women and Primary Biliary Cirrhosis

(2014) Ying Sun et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Animal Models in Primary Biliary Cirrhosis and Primary Sclerosing Cholangitis

(2014) Marion J. Pollheimer et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Emperipolesis Mediated by CD8 T Cells Is a Characteristic Histopathologic Feature of Autoimmune Hepatitis

(2014) Qi Miao et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Gal-3 regulates the capacity of dendritic cells to promote NKT-cell-induced liver injury

(2014) Vladislav Volarevic et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Ongoing activation of autoantigen-specific B cells in primary biliary cirrhosis

(2014) Jun Zhang et al.   HEPATOLOGY

Shotgun proteomics: Identification of unique protein profiles of apoptotic bodies from biliary epithelial cells

(2014) Ana Lleo et al.   HEPATOLOGY

Distinct from its canonical effects, deletion of IL-12p40 induces cholangitis and fibrosis in interleukin-2Rα−/− mice

(2014) Yuan Yao et al.   JOURNAL OF AUTOIMMUNITY

Myasthenia Gravis: Paradox versus paradigm in autoimmunity

(2014) Sonia Berrih-Aknin   JOURNAL OF AUTOIMMUNITY

From defining antigens to new therapies in multiple sclerosis: Honoring the contributions of Ruth Arnon and Michael Sela

(2014) Lawrence Steinman et al.   JOURNAL OF AUTOIMMUNITY

Galectin-3 Deficiency Reduces the Severity of Experimental Autoimmune Encephalomyelitis

(2014) H.-R. Jiang et al.   JOURNAL OF IMMUNOLOGY

Involvement of IL-13 and Tissue Transglutaminase in Liver Granuloma and Fibrosis afterSchistosoma japonicumInfection

(2014) Juanjuan Tang et al.   MEDIATORS OF INFLAMMATION

Animal Models of Primary Biliary Cirrhosis

(2014) Jinjun Wang et al.   SEMINARS IN LIVER DISEASE

Genome-Wide Analysis of DNA Methylation, Copy Number Variation, and Gene Expression in Monozygotic Twins Discordant for Primary Biliary Cirrhosis

(2014) Carlo Selmi et al.   Frontiers in Immunology

The Immunobiology and Pathophysiology of Primary Biliary Cirrhosis

(2013) Gideon M. Hirschfield et al.   Annual Review of Pathology-Mechanisms of Disease

Galectin-3 inhibition sensitizes human renal cell carcinoma cells to arsenic trioxide treatment

(2013) Yangyang Xu et al.   CANCER BIOLOGY & THERAPY

Escherichia coliinfection induces autoimmune cholangitis and anti-mitochondrial antibodies in non-obese diabetic (NOD).B6 (Idd10/Idd18) mice

(2013) J. J. Wang et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Galectin-3 Deficiency Accelerates High-Fat Diet-Induced Obesity and Amplifies Inflammation in Adipose Tissue and Pancreatic Islets

(2013) N. N. Pejnovic et al.   DIABETES

Expression of Interleukin-17 associated with disease progression and liver fibrosis with hepatitis B virus infection: IL-17 in HBV infection

(2013) Wen-Jun Du et al.   Diagnostic Pathology

IL-12/Th1 and IL-23/Th17 biliary microenvironment in primary biliary cirrhosis: Implications for therapy

(2013) Chen-Yen Yang et al.   HEPATOLOGY

Identification of Potential Cytokine Pathways for Therapeutic Intervention in Murine Primary Biliary Cirrhosis

(2013) Kazuhito Kawata et al.   PLoS One

Increased galectin-3 facilitates leukemia cell survival from apoptotic stimuli

(2011) Yi-Lin Cheng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Deletion of galectin-3 in the host attenuates metastasis of murine melanoma by modulating tumor adhesion and NK cell activity

(2011) Gordana Radosavljevic et al.   CLINICAL & EXPERIMENTAL METASTASIS

Epithelial cell specificity and apotope recognition by serum autoantibodies in primary biliary cirrhosis

(2011) Guanghua Rong et al.   HEPATOLOGY

Galectin-3 deficiency prevents concanavalin A-induced hepatitis in mice

(2011) Vladislav Volarevic et al.   HEPATOLOGY

Biliary apotopes and anti-mitochondrial antibodies activate innate immune responses in primary biliary cirrhosis

(2010) Ana Lleo et al.   HEPATOLOGY

Primary biliary cirrhosis and autoimmune hepatitis: apotopes and epitopes

(2010) Ana Lleo et al.   JOURNAL OF GASTROENTEROLOGY

Suppression of galectin-3 expression enhances apoptosis and chemosensitivity in liver fluke-associated cholangiocarcinoma

(2009) Sopit Wongkham et al.   CANCER SCIENCE

Apotopes and the biliary specificity of primary biliary cirrhosis

(2009) Ana Lleo et al.   HEPATOLOGY

Galectin-3 regulates T-cell functions

(2009) Daniel K. Hsu et al.   IMMUNOLOGICAL REVIEWS

The immunopathology of human biliary cell epithelium

(2009) Ya-Hui Chuang et al.   Seminars in Immunopathology

Targeted disruption of the galectin-3 gene results in decreased susceptibility to multiple low dose streptozotocin-induced diabetes in mice

(2008) E.P.K. Mensah-Brown et al.   CLINICAL IMMUNOLOGY

Decreased expression of galectin-3 is associated with metastatic potential of liver fluke-associated cholangiocarcinoma

(2008) Mutita Junking et al.   EUROPEAN JOURNAL OF CANCER

Adoptive transfer of CD8+ T cells from transforming growth factor beta receptor type II (dominant negative form) induces autoimmune cholangitis in mice

(2008) Guo-Xiang Yang et al.   HEPATOLOGY

Differential mechanisms in the pathogenesis of autoimmune cholangitis versus inflammatory bowel disease in interleukin-2Rα−/− mice

(2008) Willy Hsu et al.   HEPATOLOGY

Loss of tolerance in C57BL/6 mice to the autoantigen E2 subunit of pyruvate dehydrogenase by a xenobiotic with ensuing biliary ductular disease

(2008) Kanji Wakabayashi et al.   HEPATOLOGY

The consequences of apoptosis in autoimmunity

(2008) Ana Lleo et al.   JOURNAL OF AUTOIMMUNITY

Galectin-3 Protects Keratinocytes from UVB-Induced Apoptosis by Enhancing AKT Activation and Suppressing ERK Activation

(2008) Jun Saegusa et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Etiopathogenesis of primary biliary cirrhosis

(2008) Ana Lleo et al.   WORLD JOURNAL OF GASTROENTEROLOGY