siRNAmod: A database of experimentally validated chemically modified siRNAs
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
siRNAmod: A database of experimentally validated chemically modified siRNAs
Authors
Keywords
-
Journal
Scientific Reports
Volume 6, Issue 1, Pages -
Publisher
Springer Nature
Online
2016-01-28
DOI
10.1038/srep20031
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- In Vivo Activity and Duration of Short Interfering RNAs Containing a Synthetic 5′-Phosphate
- (2018) Denise M. Kenski et al. Nucleic Acid Therapeutics
- Preclinical and clinical development of siRNA-based therapeutics
- (2015) Gulnihal Ozcan et al. ADVANCED DRUG DELIVERY REVIEWS
- Enhancement of Stability and Activity of siRNA by Terminal Substitution with Serinol Nucleic Acid (SNA)
- (2014) Yukiko Kamiya et al. CHEMBIOCHEM
- Exploring Directional Invasion of Serum Nuclease into siRNA Duplexes by Asymmetrical Terminal Modifications
- (2014) Ye Huang et al. ChemMedChem
- Conjugation and Evaluation of Small Hydrophobic Molecules to Triazole-Linked siRNAs
- (2014) Brandon J. Peel et al. ACS Medicinal Chemistry Letters
- Chemistry and formulations for siRNA therapeutics
- (2013) Andrzej Gallas et al. CHEMICAL SOCIETY REVIEWS
- Chemical modifications on siRNAs avoid Toll-like-receptor-mediated activation of the hepatic immune system in vivo and in vitro
- (2013) R. Broering et al. INTERNATIONAL IMMUNOLOGY
- PubChem BioAssay: 2014 update
- (2013) Yanli Wang et al. NUCLEIC ACIDS RESEARCH
- Gene silencing by chemically modified siRNAs
- (2012) Joachim W. Engels New Biotechnology
- mRNA knockdown by single strand RNA is improved by chemical modifications
- (2012) Henry J. Haringsma et al. NUCLEIC ACIDS RESEARCH
- Intracellular stability of 2′-OMe-4′-thioribonucleoside modified siRNA leads to long-term RNAi effect
- (2012) Mayumi Takahashi et al. NUCLEIC ACIDS RESEARCH
- Comprehensive evaluation of canonical versus Dicer-substrate siRNA in vitro and in vivo
- (2012) D. J. Foster et al. RNA
- Development of Therapeutic-Grade Small Interfering RNAs by Chemical Engineering
- (2012) Jesper B. Bramsen et al. Frontiers in Genetics
- Current progress of siRNA/shRNA therapeutics in clinical trials
- (2011) John C. Burnett et al. Biotechnology Journal
- Chemical Modification of siRNA Bases To Probe and Enhance RNA Interference
- (2011) Hayden Peacock et al. JOURNAL OF ORGANIC CHEMISTRY
- Nucleoside Optimization for RNAi: A High-Throughput Platform
- (2011) Gabor Butora et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- VIRsiRNAdb: a curated database of experimentally validated viral siRNA/shRNA
- (2011) Nishant Thakur et al. NUCLEIC ACIDS RESEARCH
- HIVsirDB: A Database of HIV Inhibiting siRNAs
- (2011) Atul Tyagi et al. PLoS One
- Modified siRNAs for the study of the PAZ domain
- (2010) Álvaro Somoza et al. CHEMICAL COMMUNICATIONS
- Recent Progress in Chemically Modified siRNAs
- (2010) M. Gaglione et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
- (2010) Mark E. Davis et al. NATURE
- The RNA modification database, RNAMDB: 2011 update
- (2010) W. A. Cantara et al. NUCLEIC ACIDS RESEARCH
- RNAi and small interfering RNAs in human disease therapeutic applications
- (2010) Monica R. Lares et al. TRENDS IN BIOTECHNOLOGY
- UNA (unlocked nucleic acid): A flexible RNA mimic that allows engineering of nucleic acid duplex stability
- (2009) Niels Langkjær et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Phosphorothioate-Stimulated Uptake of siRNA by Mammalian Cells: A Novel Route for Delivery
- (2009) Anke Detzer et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Analysis of acyclic nucleoside modifications in siRNAs finds sensitivity at position 1 that is restored by 5′-terminal phosphorylation both in vitro and in vivo
- (2009) Denise M. Kenski et al. NUCLEIC ACIDS RESEARCH
- A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity
- (2009) Jesper B. Bramsen et al. NUCLEIC ACIDS RESEARCH
- Naked siLNA-Mediated Gene Silencing of Lung Bronchoepithelium EGFP Expression After Intravenous Administration
- (2009) Sys Zoffmann Glud et al. OLIGONUCLEOTIDES
- Steric Effects in RNA Interference: Probing the Influence of Nucleobase Size and Shape
- (2008) Alvaro Somoza et al. CHEMISTRY-A EUROPEAN JOURNAL
- Phosphorothioate-Stimulated Cellular Uptake of siRNA: A Cell Culture Model for Mechanistic Studies
- (2008) A. Detzer et al. CURRENT PHARMACEUTICAL DESIGN
- RNA Interference in Mammalia Cells by RNA-3’-PNA Chimeras
- (2008) Nicoletta Potenza et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- siRecords: a database of mammalian RNAi experiments and efficacies
- (2008) Y. Ren et al. NUCLEIC ACIDS RESEARCH
- Chemical Modification Patterns Compatible with High Potency Dicer-Substrate Small Interfering RNAs
- (2008) Michael A. Collingwood et al. OLIGONUCLEOTIDES
- Nucleoside modifications modulate activation of the protein kinase PKR in an RNA structure-specific manner
- (2008) S. R. Nallagatla et al. RNA
- Synthesis of 2′-O-modified adenosine building blocks and application for RNA interference
- (2007) Dalibor Odadzic et al. BIOORGANIC & MEDICINAL CHEMISTRY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started