Susceptibility of outer hair cells to cholesterol chelator 2-hydroxypropyl-β-cyclodextrine is prestin-dependent

Dynamics of cochlear synaptopathy after acoustic overexposure

(2015) Leslie D. Liberman et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

Hearing Loss and Otopathology Following Systemic and Intracerebroventricular Delivery of 2-Hydroxypropyl-Beta-Cyclodextrin

(2015) Scott Cronin et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

Outer Hair Cell Lateral Wall Structure Constrains the Mobility of Plasma Membrane Proteins

(2015) Tetsuji Yamashita et al.   PLoS Genetics

Prestin-Dependence of Outer Hair Cell Survival and Partial Rescue of Outer Hair Cell Loss in PrestinV499G/Y501H Knockin Mice

(2015) Mary Ann Cheatham et al.   PLoS One

Collaborative Development of 2-Hydroxypropyl-β-Cyclodextrin for the Treatment of Niemann-Pick Type C1 Disease

(2014) Elizabeth Ottinger et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Loss of the Tectorial Membrane Protein CEACAM16 Enhances Spontaneous, Stimulus-Frequency, and Transiently Evoked Otoacoustic Emissions

(2014) M. A. Cheatham et al.   JOURNAL OF NEUROSCIENCE

Lysosomal-specific Cholesterol Reduction by Biocleavable Polyrotaxanes for Ameliorating Niemann-Pick Type C Disease

(2014) Atsushi Tamura et al.   Scientific Reports

Cholesterol binding to ion channels

(2014) Irena Levitan et al.   Frontiers in Physiology

Interaction between the Marine Sponge Cyclic Peptide Theonellamide A and Sterols in Lipid Bilayers As Viewed by Surface Plasmon Resonance and Solid-State 2H Nuclear Magnetic Resonance

(2013) Rafael Atillo Espiritu et al.   BIOCHEMISTRY

Auditory Phenotype of Niemann-Pick Disease, Type C1

(2013) Kelly A. King et al.   EAR AND HEARING

Cyclodextrin alleviates neuronal storage of cholesterol in Niemann-Pick C disease without evidence of detectable blood–brain barrier permeability

(2013) Charles C. Pontikis et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Olivocochlear suppression of outer hair cells in vivo: evidence for combined action of BK and SK2 channels throughout the cochlea

(2013) Stéphane F. Maison et al.   JOURNAL OF NEUROPHYSIOLOGY

The SLC26 gene family of anion transporters and channels

(2013) Seth L. Alper et al.   MOLECULAR ASPECTS OF MEDICINE

Visualization of Sterol-Rich Membrane Domains with Fluorescently-Labeled Theonellamides

(2013) Shinichi Nishimura et al.   PLoS One

Hearing Loss and Hair Cell Death in Mice Given the Cholesterol-Chelating Agent Hydroxypropyl-β-Cyclodextrin

(2012) Mark A. Crumling et al.   PLoS One

Effect of membrane mechanics on charge transfer by the membrane protein prestin

(2011) Natalie Nilsen et al.   Biomechanics and Modeling in Mechanobiology

Prestin in HEK cells is an obligate tetramer

(2011) Richard Hallworth et al.   JOURNAL OF NEUROPHYSIOLOGY

Unesterified Cholesterol Accumulation in Late Endosomes/Lysosomes Causes Neurodegeneration and Is Prevented by Driving Cholesterol Export from This Compartment

(2011) A. Aqul et al.   JOURNAL OF NEUROSCIENCE

Membrane cholesterol modulates cochlear electromechanics

(2011) William E. Brownell et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Cholesterol Influences Voltage-Gated Calcium Channels and BK-Type Potassium Channels in Auditory Hair Cells

(2011) Erin K. Purcell et al.   PLoS One

A highly expressing Tet-inducible cell line recapitulates in situ developmental changes in prestin's Boltzmann characteristics and reveals early maturational events

(2010) Shumin Bian et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Sensitivity of Prestin-Based Membrane Motor to Membrane Thickness

(2010) Jie Fang et al.   BIOPHYSICAL JOURNAL

Evidence That Prestin Has at Least Two Voltage-dependent Steps

(2010) Kazuaki Homma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Marine antifungal theonellamides target 3β-hydroxysterol to activate Rho1 signaling

(2010) Shinichi Nishimura et al.   Nature Chemical Biology

The influence of cholesterol on the motility of cochlear outer hair cells and the motor protein prestin

(2009) M. Canis et al.   ACTA OTO-LARYNGOLOGICA

Changes in plasma membrane structure and electromotile properties in prestin deficient outer hair cells

(2009) David Z.Z. He et al.   Cytoskeleton

Glycosylation Regulates Prestin Cellular Activity

(2009) Lavanya Rajagopalan et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

Cyclodextrin overcomes deficient lysosome-to-endoplasmic reticulum transport of cholesterol in Niemann-Pick type C cells

(2009) L. Abi-Mosleh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane Composition Modulates Prestin-associated Charge Movement

(2008) John Sfondouris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prestin-Based Outer Hair Cell Motility Is Necessary for Mammalian Cochlear Amplification

(2008) Peter Dallos et al.   NEURON

Cochlear Outer Hair Cell Motility

(2008) Jonathan Ashmore   PHYSIOLOGICAL REVIEWS