Genetic studies of plasma analytes identify novel potential biomarkers for several complex traits

Effects of a recruitment maneuver on plasma levels of soluble RAGE in patients with diffuse acute respiratory distress syndrome: a prospective randomized crossover study

(2015) Matthieu Jabaudon et al.   INTENSIVE CARE MEDICINE

Effect of predicted protein-truncating genetic variants on the human transcriptome

(2015) M. A. Rivas et al.   SCIENCE

Polymorphism of the cystatin C gene in patients with acute coronary syndromes: Results from the PLATelet inhibition and patient Outcomes study

(2014) Axel Åkerblom et al.   AMERICAN HEART JOURNAL

Phosphorylated Tau-Aβ 42 Ratio as a Continuous Trait for Biomarker Discovery for Early-Stage Alzheimer’s Disease in Multiplex Immunoassay Panels of Cerebrospinal Fluid

(2014) Oscar Harari et al.   BIOLOGICAL PSYCHIATRY

Multiancestral Analysis of Inflammation-Related Genetic Variants and C-Reactive Protein in the Population Architecture Using Genomics and Epidemiology Study

(2014) J. M. Kocarnik et al.   Circulation-Cardiovascular Genetics

Variation atABOhisto-blood group andFUTloci and diffuse and intestinal gastric cancer risk in a European population

(2014) Eric J. Duell et al.   INTERNATIONAL JOURNAL OF CANCER

An atlas of genetic influences on human blood metabolites

(2014) So-Youn Shin et al.   NATURE GENETICS

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

(2014) Anubha Mahajan et al.   NATURE GENETICS

Genetic Variations Affecting Serum Carcinoembryonic Antigen Levels and Status of Regional Lymph Nodes in Patients with Sporadic Colorectal Cancer from Southern China

(2014) Yu Liang et al.   PLoS One

Adipocyte-Specific IKKβ Signaling Suppresses Adipose Tissue Inflammation through an IL-13-Dependent Paracrine Feedback Pathway

(2014) Hyokjoon Kwon et al.   Cell Reports

Genetic Determinants Influencing Human Serum Metabolome among African Americans

(2014) Bing Yu et al.   PLoS Genetics

Genome-Wide Association Study of CSF Levels of 59 Alzheimer's Disease Candidate Proteins: Significant Associations with Proteins Involved in Amyloid Processing and Inflammation

(2014) John S. K. Kauwe et al.   PLoS Genetics

Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality

(2013) Ilkka Seppälä et al.   EUROPEAN HEART JOURNAL

A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk

(2013) Meian He et al.   GUT

Systems genetics approaches to understand complex traits

(2013) Mete Civelek et al.   NATURE REVIEWS GENETICS

GWAS of Cerebrospinal Fluid Tau Levels Identifies Risk Variants for Alzheimer’s Disease

(2013) Carlos Cruchaga et al.   NEURON

Influence of Genetic Variation on Plasma Protein Levels in Older Adults Using a Multi-Analyte Panel

(2013) Sungeun Kim et al.   PLoS One

Annotation of functional variation in personal genomes using RegulomeDB

(2012) A. P. Boyle et al.   GENOME RESEARCH

Cerebrospinal fluid APOE levels: an endophenotype for genetic studies for Alzheimer's disease

(2012) Carlos Cruchaga et al.   HUMAN MOLECULAR GENETICS

Identification of cis-regulatory variation influencing protein abundance levels in human plasma

(2012) Anbarasu Lourdusamy et al.   HUMAN MOLECULAR GENETICS

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Genome-wide association study identifies multiple loci influencing human serum metabolite levels

(2012) Johannes Kettunen et al.   NATURE GENETICS

Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease

(2012) W. T. Hu et al.   NEUROLOGY

SNPnexus: a web server for functional annotation of novel and publicly known genetic variants (2012 update)

(2012) A. Z. Dayem Ullah et al.   NUCLEIC ACIDS RESEARCH

A Genome-Wide Association Study Identifies rs2000999 as a Strong Genetic Determinant of Circulating Haptoglobin Levels

(2012) Philippe Froguel et al.   PLoS One

Genetic Association Analysis of Complex Diseases Incorporating Intermediate Phenotype Information

(2012) Yafang Li et al.   PLoS One

Linkage analysis identifies a locus for plasma von Willebrand factor undetected by genome-wide association

(2012) K. C. Desch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Genome-Wide Association Study of Monozygotic Twin-Pairs Suggests a Locus Related to Variability of Serum High-Density Lipoprotein Cholesterol

(2012) Ida Surakka et al.   Twin Research and Human Genetics

Novel Loci for Metabolic Networks and Multi-Tissue Expression Studies Reveal Genes for Atherosclerosis

(2012) Michael Inouye et al.   PLoS Genetics

Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci

(2011) Nikolaos A. Patsopoulos et al.   ANNALS OF NEUROLOGY

Genetic variants, plasma lipoprotein(a) levels, and risk of cardiovascular morbidity and mortality among two prospective cohorts of type 2 diabetes

(2011) Qibin Qi et al.   EUROPEAN HEART JOURNAL

Fine Mapping of Genetic Variants in BIN1, CLU, CR1 and PICALM for Association with Cerebrospinal Fluid Biomarkers for Alzheimer's Disease

(2011) John S. K. Kauwe et al.   PLoS One

Alzheimer's Disease Neuroimaging Initiative biomarkers as quantitative phenotypes: Genetics core aims, progress, and plans

(2010) Andrew J. Saykin et al.   Alzheimers & Dementia

Changes in B- and T-Lymphocyte and Chemokine Levels With Rituximab Treatment in Multiple Sclerosis

(2010) Laura Piccio et al.   ARCHIVES OF NEUROLOGY

LocusZoom: regional visualization of genome-wide association scan results

(2010) R. J. Pruim et al.   BIOINFORMATICS

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

Genetic variants in ABO blood group region, plasma soluble E-selectin levels and risk of type 2 diabetes

(2010) Lu Qi et al.   HUMAN MOLECULAR GENETICS

Identification of Quantitative Trait Loci Underlying Proteome Variation in Human Lymphoblastoid Cells

(2010) Nikhil Garge et al.   MOLECULAR & CELLULAR PROTEOMICS

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

A genome-wide association study identifies new loci for ACE activity: potential implications for response to ACE inhibitor

(2010) C-M Chung et al.   PHARMACOGENOMICS JOURNAL

Genome-Wide Association Identifies the ABO Blood Group as a Major Locus Associated With Serum Levels of Soluble E-Selectin

(2009) Andrew D. Paterson et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20

(2009) Melanie Bahlo et al.   NATURE GENETICS

Genome-wide association study identifies five loci associated with lung function

(2009) Emmanouela Repapi et al.   NATURE GENETICS

Increased cerebrospinal fluid concentrations of the chemokine CXCL13 in active MS

(2009) F. Sellebjerg et al.   NEUROLOGY

Variants in TF and HFE Explain ∼40% of Genetic Variation in Serum-Transferrin Levels

(2008) Beben Benyamin et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Assessing the validity of a statistical distribution: some illustrative examples from dermatological research

(2008) B. Sürücü et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Alzheimer’s disease risk variants show association with cerebrospinal fluid amyloid beta

(2008) John S. K. Kauwe et al.   NEUROGENETICS

Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum

(2008) Christian Gieger et al.   PLoS Genetics

A Genome-Wide Association Study Identifies Protein Quantitative Trait Loci (pQTLs)

(2008) David Melzer et al.   PLoS Genetics