NAMPT and NAPRT1: novel polymorphisms and distribution of variants between normal tissues and tumor samples

Synonymous Mutations Frequently Act as Driver Mutations in Human Cancers

(2014) Fran Supek et al.   CELL

Detection and replication of epistasis influencing transcription in humans

(2014) Gibran Hemani et al.   NATURE

A general framework for estimating the relative pathogenicity of human genetic variants

(2014) Martin Kircher et al.   NATURE GENETICS

Loss of NAPRT1 Expression by Tumor-Specific Promoter Methylation Provides a Novel Predictive Biomarker for NAMPT Inhibitors

(2013) D. S. Shames et al.   CLINICAL CANCER RESEARCH

NAD+ salvage pathway proteins suppress proteotoxicity in yeast models of neurodegeneration by promoting the clearance of misfolded/oligomerized proteins

(2013) Alejandro Ocampo et al.   HUMAN MOLECULAR GENETICS

Ensembl 2014

(2013) Paul Flicek et al.   NUCLEIC ACIDS RESEARCH

Visfatin/NAMPT: A Multifaceted Molecule with Diverse Roles in Physiology and Pathophysiology

(2012) Tuva B. Dahl et al.   Annual Review of Nutrition

Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT) Activity by Small Molecule GMX1778 Regulates Reactive Oxygen Species (ROS)-mediated Cytotoxicity in a p53- and Nicotinic Acid Phosphoribosyltransferase1 (NAPRT1)-dependent Manner

(2012) David Cerna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CDD: conserved domains and protein three-dimensional structure

(2012) Aron Marchler-Bauer et al.   NUCLEIC ACIDS RESEARCH

Expression patterns of nicotinamide phosphoribosyltransferase and nicotinic acid phosphoribosyltransferase in human malignant lymphomas

(2011) UFFE HØGH OLESEN et al.   APMIS

Characterization of human nicotinate phosphoribosyltransferase: Kinetic studies, structure prediction and functional analysis by site-directed mutagenesis

(2011) Lucia Galassi et al.   BIOCHIMIE

Nicotinamide Phosphoribosyltransferase: A Potent Therapeutic Target in Non-small Cell Lung Cancer with Epidermal Growth Factor Receptor-Gene Mutation

(2011) Shunsuke Okumura et al.   Journal of Thoracic Oncology

Understanding the contribution of synonymous mutations to human disease

(2011) Zuben E. Sauna et al.   NATURE REVIEWS GENETICS

PBEF1/NAmPRTase/Visfatin: A potential malignant astrocytoma/glioblastoma serum marker with prognostic value

(2010) P. Sreekanth Reddy et al.   CANCER BIOLOGY & THERAPY

Mapping of numerous disease-associated expression polymorphisms in primary peripheral blood CD4+ lymphocytes

(2010) Amy Murphy et al.   HUMAN MOLECULAR GENETICS

A polymorphism in the visfatin gene promoter is related to decreased plasma levels of inflammatory markers in patients with coronary artery disease

(2010) Lian-Sheng Wang et al.   MOLECULAR BIOLOGY REPORTS

A Preclinical Study on the Rescue of Normal Tissue by Nicotinic Acid in High-Dose Treatment with APO866, a Specific Nicotinamide Phosphoribosyltransferase Inhibitor

(2010) U. H. Olesen et al.   MOLECULAR CANCER THERAPEUTICS

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

I-TASSER: a unified platform for automated protein structure and function prediction

(2010) Ambrish Roy et al.   Nature Protocols

Visfatin, glucose metabolism and vascular disease: a review of evidence

(2010) Pedro Saddi-Rosa et al.   Diabetology & Metabolic Syndrome

Structure and reaction mechanism of human nicotinamide phosphoribosyltransferase

(2009) Ryo Takahashi et al.   JOURNAL OF BIOCHEMISTRY

The Small Molecule GMX1778 Is a Potent Inhibitor of NAD+ Biosynthesis: Strategy for Enhanced Therapy in Nicotinic Acid Phosphoribosyltransferase 1-Deficient Tumors

(2009) M. Watson et al.   MOLECULAR AND CELLULAR BIOLOGY

A phosphoenzyme mimic, overlapping catalytic sites and reaction coordinate motion for human NAMPT

(2009) E. S. Burgos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide association scan of the time to onset of attention deficit hyperactivity disorder

(2008) Jessica Lasky-Su et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Nicotinic Acid, Nicotinamide, and Nicotinamide Riboside: A Molecular Evaluation of NAD+ Precursor Vitamins in Human Nutrition

(2008) Katrina L Bogan et al.   Annual Review of Nutrition

I-TASSER server for protein 3D structure prediction

(2008) Yang Zhang   BMC BIOINFORMATICS

The visfatin (PBEF1) G-948T gene polymorphism is associated with increased high-density lipoprotein cholesterol in obese subjects

(2008) Lina M. Johansson et al.   METABOLISM-CLINICAL AND EXPERIMENTAL