NAD+ salvage pathway proteins suppress proteotoxicity in yeast models of neurodegeneration by promoting the clearance of misfolded/oligomerized proteins

Mislocalization of neuronal mitochondria reveals regulation of Wallerian degeneration and NMNAT/WLDS-mediated axon protection independent of axonal mitochondria

(2013) Brandon M. Kitay et al.   HUMAN MOLECULAR GENETICS

Mitochondrial Respiratory Thresholds Regulate Yeast Chronological Life Span and its Extension by Caloric Restriction

(2012) Alejandro Ocampo et al.   Cell Metabolism

A Novel Drosophila Model of Nerve Injury Reveals an Essential Role of Nmnat in Maintaining Axonal Integrity

(2012) Yanshan Fang et al.   CURRENT BIOLOGY

WldS Prevents Axon Degeneration through Increased Mitochondrial Flux and Enhanced Mitochondrial Ca2+ Buffering

(2012) Michelle A. Avery et al.   CURRENT BIOLOGY

CREB-activity and nmnat2 transcription are down-regulated prior to neurodegeneration, while NMNAT2 over-expression is neuroprotective, in a mouse model of human tauopathy

(2011) M. Cecilia Ljungberg et al.   HUMAN MOLECULAR GENETICS

NMNAT suppresses Tau-induced neurodegeneration by promoting clearance of hyperphosphorylated Tau oligomers in a Drosophila model of tauopathy

(2011) Yousuf O. Ali et al.   HUMAN MOLECULAR GENETICS

Nicotinamide Mononucleotide Adenylyltransferase Is a Stress Response Protein Regulated by the Heat Shock Factor/Hypoxia-inducible Factor 1α Pathway

(2011) Yousuf O. Ali et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nmnat exerts neuroprotective effects in dendrites and axons

(2011) Yuhui Wen et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Nicotinamide mononucleotide adenylyl transferase 1 protects against acute neurodegeneration in developing CNS by inhibiting excitotoxic-necrotic cell death

(2011) P. B. Verghese et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wallerian Degeneration, WldS, and Nmnat

(2010) Michael P. Coleman et al.   Annual Review of Neuroscience

Endogenous Nmnat2 Is an Essential Survival Factor for Maintenance of Healthy Axons

(2010) Jonathan Gilley et al.   PLOS BIOLOGY

Enhanced degradation of mutant huntingtin by rho kinase inhibition is mediated through activation of proteasome and macroautophagy

(2009) Peter O. Bauer et al.   Autophagy

Suppression of polyglutamine-induced cytotoxicity in Saccharomyces cerevisiae by enhancement of mitochondrial biogenesis

(2009) Alejandro Ocampo et al.   FASEB JOURNAL

Nicotinamide Mononucleotide Adenylyltransferase Expression in Mitochondrial Matrix Delays Wallerian Degeneration

(2009) N. Yahata et al.   JOURNAL OF NEUROSCIENCE

Transgenic Mice Expressing the Nmnat1 Protein Manifest Robust Delay in Axonal Degeneration In Vivo

(2009) Y. Sasaki et al.   JOURNAL OF NEUROSCIENCE

Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies

(2008) S Sarkar et al.   CELL DEATH AND DIFFERENTIATION

Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity

(2008) M. L. Duennwald et al.   GENES & DEVELOPMENT

Pnc1p-Mediated Nicotinamide Clearance Modifies the Epigenetic Properties of rDNA Silencing in Saccharomyces cerevisiae

(2008) J. M. McClure et al.   GENETICS

NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration

(2008) R. Grace Zhai et al.   NATURE

NAD+/NADH and NADP+/NADPH in Cellular Functions and Cell Death: Regulation and Biological Consequences

(2007) Weihai Ying   ANTIOXIDANTS & REDOX SIGNALING