Combinatorial bio-conjugation of gemcitabine and curcumin enables dual drug delivery with synergistic anticancer efficacy and reduced toxicity

Macromolecular Bipill of Gemcitabine and Methotrexate Facilitates Tumor-Specific Dual Drug Therapy with Higher Benefit-to-Risk Ratio

(2014) Manasmita Das et al.   BIOCONJUGATE CHEMISTRY

Novel self-nanoemulsifying formulation of quercetin: Implications of pro-oxidant activity on the anticancer efficacy

(2014) Amit K. Jain et al.   Nanomedicine-Nanotechnology Biology and Medicine

Enhanced Transfection Efficiency and Reduced Cytotoxicity of Novel Lipid–Polymer Hybrid Nanoplexes

(2013) Sanyog Jain et al.   MOLECULAR PHARMACEUTICS

Augmented Anticancer Activity of a Targeted, Intracellularly Activatable, Theranostic Nanomedicine Based on Fluorescent and Radiolabeled, Methotrexate-Folic Acid-Multiwalled Carbon Nanotube Conjugate

(2013) Manasmita Das et al.   MOLECULAR PHARMACEUTICS

Co-encapsulation of Tamoxifen and Quercetin in Polymeric Nanoparticles: Implications on Oral Bioavailability, Antitumor Efficacy, and Drug-Induced Toxicity

(2013) Amit K. Jain et al.   MOLECULAR PHARMACEUTICS

Solidified Self-Nanoemulsifying Formulation for Oral Delivery of Combinatorial Therapeutic Regimen: Part II In vivo Pharmacokinetics, Antitumor Efficacy and Hepatotoxicity

(2013) Amit K. Jain et al.   PHARMACEUTICAL RESEARCH

Solidified Self-Nanoemulsifying Formulation for Oral Delivery of Combinatorial Therapeutic Regimen: Part I. Formulation Development, Statistical Optimization, and In Vitro Characterization

(2013) Amit K. Jain et al.   PHARMACEUTICAL RESEARCH

Effect of co-administration of CoQ10-loaded nanoparticles on the efficacy and cardiotoxicity of doxorubicin-loaded nanoparticles

(2013) Nitin K. Swarnakar et al.   RSC Advances

Polyelectrolyte stabilized multilayered liposomes for oral delivery of paclitaxel

(2012) Sanyog Jain et al.   BIOMATERIALS

Oral Delivery of Doxorubicin Using Novel Polyelectrolyte-Stabilized Liposomes (Layersomes)

(2012) Sanyog Jain et al.   MOLECULAR PHARMACEUTICS

Oral bioavailability, therapeutic efficacy and reactive oxygen species scavenging properties of coenzyme Q10-loaded polymeric nanoparticles

(2011) Nitin K. Swarnakar et al.   BIOMATERIALS

Improved plasma stability and sustained release profile of gemcitabine via polypeptide conjugation

(2010) Lik-Voon Kiew et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Curcumin-loaded PLGA-PEG-PLGA triblock copolymeric micelles: Preparation, pharmacokinetics and distribution in vivo

(2010) Zhimei Song et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Combinatorial Drug Conjugation Enables Nanoparticle Dual-Drug Delivery

(2010) Santosh Aryal et al.   Small

Gemcitabine and paclitaxel every 2 weeks in patients with previously untreated urothelial carcinoma

(2009) Fabio Calabrò et al.   CANCER

Synergistic drug combinations tend to improve therapeutically relevant selectivity

(2009) Joseph Lehár et al.   NATURE BIOTECHNOLOGY

Squalenoylation Favorably Modifies the in Vivo Pharmacokinetics and Biodistribution of Gemcitabine in Mice

(2008) L. H. Reddy et al.   DRUG METABOLISM AND DISPOSITION

Antitumoral activity of PEG–gemcitabine prodrugs targeted by folic acid

(2008) Gianfranco Pasut et al.   JOURNAL OF CONTROLLED RELEASE

Preclinical Toxicology (Subacute and Acute) and Efficacy of a New Squalenoyl Gemcitabine Anticancer Nanomedicine

(2008) L. H. Reddy et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS