One-pot, telescoped synthesis of N-aryl-5-aminopyrazoles from anilines in environmentally benign conditions

Asymmetric synthesis of the four diastereoisomers of a novel non-steroidal farnesoid X receptor (FXR) agonist: Role of the chirality on the biological activity

(2013) Maura Marinozzi et al.   BIOORGANIC & MEDICINAL CHEMISTRY

One-pot Synthesis and its Practical Application in Pharmaceutical Industry

(2013) Wenyi Zhao et al.   CURRENT ORGANIC SYNTHESIS

Jaguar: A high-performance quantum chemistry software program with strengths in life and materials sciences

(2013) Art D. Bochevarov et al.   INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY

Pyrazole[3,4-e][1,4]thiazepin-7-one derivatives as a novel class of Farnesoid X Receptor (FXR) agonists

(2012) Maura Marinozzi et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Discovery of a Novel Alpha-7 Nicotinic Acetylcholine Receptor Agonist Series and Characterization of the Potent, Selective, and Orally Efficacious Agonist 5-(4-Acetyl[1,4]diazepan-1-yl)pentanoic Acid [5-(4-Methoxyphenyl)-1H-pyrazol-3-yl] Amide (SEN15924, WAY-361789)

(2012) Riccardo Zanaletti et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Imidazo[4,5-c]pyrazoles via Copper-Catalyzed Amidine Cyclization

(2012) Kostiantyn Liubchak et al.   JOURNAL OF ORGANIC CHEMISTRY

High Throughput Synthesis of Extended Pyrazolo[3,4-d]dihydropyrimidines

(2012) Sergey V. Ryabukhin et al.   ACS Combinatorial Science

Approaches towards the synthesis of 5-aminopyrazoles

(2011) Ranjana Aggarwal et al.   Beilstein Journal of Organic Chemistry

Tin (IV) Chloride-Promoted One-Pot Synthesis of Novel Tacrine Analogues

(2011) Huanan Hu et al.   MOLECULES

Synthesis of novel 3,4-diaryl-5-aminopyrazoles as potential kinase inhibitors

(2011) Larry T. Pierce et al.   TETRAHEDRON

Piecing together the puzzle: understanding a mild, metal free reduction method for the large scale synthesis of hydrazines

(2011) Duncan L. Browne et al.   TETRAHEDRON

Identification and optimization of substituted 5-aminopyrazoles as potent and selective adenosine A1 receptor antagonists

(2010) Nils Griebenow et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Second-Generation Process Research Towards Eletriptan: A Fischer Indole Approach

(2010) Christopher P. Ashcroft et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Theoretical evidence for a two-step mechanism in the functionalization single-walled carbon nanotube by aryl diazonium salts: Comparing effect of different substituent group

(2009) Hongming Wang et al.   CHEMICAL PHYSICS LETTERS

An Efficient One-Step Synthesis of Heterobiaryl Pyrazolo[3,4-b]pyridines via Indole Ring Opening

(2009) Sanghee Lee et al.   ORGANIC LETTERS

Tuning of Chemo- and Regioselectivities in Multicomponent Condensations of 5-Aminopyrazoles, Dimedone, and Aldehydes

(2008) Valentin A. Chebanov et al.   JOURNAL OF ORGANIC CHEMISTRY

Heavy-Metal-Free Reduction Methodology for Large-Scale Synthesis Applicable to Heterocyclic and Arylhydrazines†

(2008) Timothy Norris et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT