Journal
RSC ADVANCES
Volume 4, Issue 5, Pages 2274-2283Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3ra44798g
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- National Science Council of the Republic of China [NSC 100-2113-M-003-008-MY3]
- National Taiwan Normal University [99T3030-2, 99-D, 100-D-06]
- Instrumentation Centre at National Taiwan Normal University
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The synthesis of indolo[1,2-a]quinazolinone starting from 2-iodobenzamide and indole derivatives is reported. In this two-step procedure, indole is N-arylated with 2-iodobenzamide derivatives via Ullman coupling, followed by an intramolecular C-H amidation using a palladium catalyst.
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