4.6 Article

Automatic reactor for solid-phase synthesis of molecularly imprinted polymeric nanoparticles (MIP NPs) in water

Journal

RSC ADVANCES
Volume 4, Issue 8, Pages 4203-4206

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3ra46838k

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Funding

  1. Royal Society (Brian Mercer Feasibility Award)
  2. Wellcome Trust (UK) (Translational Award)

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We report the development of an automated chemical reactor for solid-phase synthesis of MIP NPs in water. Operational parameters are under computer control, requiring minimal operator intervention. In this study, ready for use MIP NPs with sub-nanomolar affinity are prepared against pepsin A, trypsin and a-amylase in only 4 hours.

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