A biologically relevant ceramide fluorescent probe to assess the binding of potential ligands to the CERT transfer protein

Revised Stereochemistry of Ceramide-Trafficking Inhibitor HPA-12 by X-ray Crystallography Analysis

(2013) Masaharu Ueno et al.   ORGANIC LETTERS

Ceramide Transfer Protein and Cancer

(2012) Luana Scheffer et al.   Anti-Cancer Agents in Medicinal Chemistry

Novel fluorescent ceramide derivatives for probing ceramidase substrate specificity

(2012) Krishna P. Bhabak et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Limonoid Compounds Inhibit Sphingomyelin Biosynthesis by Preventing CERT Protein-dependent Extraction of Ceramides from the Endoplasmic Reticulum

(2012) Françoise Hullin-Matsuda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sphingosine Kinase Inhibitors and Cancer: Seeking the Golden Sword of Hercules

(2011) S. Pyne et al.   CANCER RESEARCH

Expedient and Practical Synthesis of CERT-Dependent Ceramide Trafficking Inhibitor HPA-12 and Its Analogues

(2011) Andrej Ďuriš et al.   ORGANIC LETTERS

Development of small-molecule inhibitors of sphingosine-1-phosphate signaling

(2011) Yvette Edmonds et al.   PHARMACOLOGY & THERAPEUTICS

Regulation of Death and Growth Signals at the Plasma Membrane by Sphingomyelin Synthesis: Implications for Hematological Malignancies

(2011) Elodie Lafont et al.   Recent Patents on Anti-Cancer Drug Discovery

Newly synthetic ceramide-1-phosphate analogs; their uptake, intracellular localization, and roles as an inhibitor of cytosolic phospholipase A2α and inducer of cell toxicity

(2010) Tomohiko Makiyama et al.   BIOCHEMICAL PHARMACOLOGY

The intermembrane ceramide transport catalyzed by CERT is sensitive to the lipid environment

(2010) Jessica Tuuf et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The Acid Sphingomyelinase/Ceramide Pathway: Biomedical Significance and Mechanisms of Regulation

(2010) Y.H. Zeidan et al.   CURRENT MOLECULAR MEDICINE

Sphingolipids and cancer: ceramide and sphingosine-1-phosphate in the regulation of cell death and drug resistance

(2010) Suriyan Ponnusamy et al.   Future Oncology

Mammalian Neutral Sphingomyelinases: Regulation and Roles in Cell Signaling Responses

(2010) Bill X. Wu et al.   NEUROMOLECULAR MEDICINE

Flexible and enantioselective access to jaspine B and biologically active chain-modified analogues thereof

(2010) Yahya Salma et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Intracellular trafficking of ceramide by ceramide transfer protein

(2010) Kentaro HANADA   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Real-time assay method of lipid extraction activity

(2009) Toshihiko Sugiki et al.   ANALYTICAL BIOCHEMISTRY

The natural marine anhydrophytosphingosine, Jaspine B, induces apoptosis in melanoma cells by interfering with ceramide metabolism

(2009) Yahya Salma et al.   BIOCHEMICAL PHARMACOLOGY

CERT-mediated trafficking of ceramide

(2009) Kentaro Hanada et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Inhibition of Sphingomyelin Hydrolysis: Targeting the Lipid Mediator Ceramide as a Key Regulator of Cellular Fate

(2009) Ralf Claus et al.   CURRENT MEDICINAL CHEMISTRY

Empirical Scoring Functions for Advanced Protein−Ligand Docking with PLANTS

(2009) Oliver Korb et al.   Journal of Chemical Information and Modeling

Crystal Structures of the CERT START Domain with Inhibitors Provide Insights into the Mechanism of Ceramide Transfer

(2009) Norio Kudo et al.   JOURNAL OF MOLECULAR BIOLOGY

Effects of ceramide and other simple sphingolipids on membrane lateral structure

(2008) Félix M. Goñi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Decreased Ceramide Transport Protein (CERT) Function Alters Sphingomyelin Production following UVB Irradiation

(2008) Alexandra Charruyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Principles of bioactive lipid signalling: lessons from sphingolipids

(2008) Yusuf A. Hannun et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural basis for specific lipid recognition by CERT responsible for nonvesicular trafficking of ceramide

(2008) N. Kudo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemical synthesis of fluorescent glycero- and sphingolipids

(2008) J RASMUSSEN et al.   PROGRESS IN LIPID RESEARCH

Syntheses of sphingomyelin methylene, aza, and sulfur analogues by the versatile olefin cross-metathesis method

(2008) Tetsuya Yamamoto et al.   TETRAHEDRON

Medicinal Chemistry Aspects of Drug Targets in Sphingolipid Metabolism

(2007) Peter Nussbaumer   ChemMedChem

Acid ceramidase inhibition: a novel target for cancer therapy

(2007) Xiang Liu   Frontiers in Bioscience-Landmark