Article
Polymer Science
Balakondareddy Sana, Nancy Ferrentino, Taha Behroozi Kohlan, Yaqun Liu, Valdas Pasiskevicius, Anna Finne-Wistrand, Daniela Pappalardo
Summary: We have designed a light-sensitive polymer material that self-assembles into core-shell nanoparticles and releases encapsulated fluorescent dye upon light irradiation.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Polymer Science
Leonard Ionut Atanase, Slim Salhi, Oana Cucoveica, Marijana Ponjavic, Jasmina Nikodinovic-Runic, Christelle Delaite
Summary: Biodegradable polymers have great significance in biomedical applications as they can degrade in the body, eliminating the need for retrieval or explant. This study obtained a series of PCL-b-PEA-b-PCL block copolymers with varying PCL sequence lengths, and found that the presence of the PEA central sequence has an important influence on the biodegradability of the copolymer samples.
Article
Polymer Science
Victor Delorme, Ghislain David, Stephane Dejean, Julia Mouton, Xavier Garric, Jean Coudane, Helene van den Berghe
Summary: Describes the synthesis of a fully biodegradable amphiphilic copolymer PCL-g-CHT, which has a hydrophobic PCL backbone and hydrophilic CHT grafts. The copolymer self-assembles into nanomicelles and can be used for novel drug delivery systems.
MACROMOLECULAR RAPID COMMUNICATIONS
(2023)
Article
Polymer Science
Kevin Hagmann, Carolin Bunk, Frank Boehme, Regine von Klitzing
Summary: The preparation and investigation of gel films from a model amphiphilic polymer conetwork provide a better understanding of the structure-property relationship in both bulk phase and interfacial materials. The study finds that the polarity of solvents affects the swelling ability, surface structure, and mechanical properties of the gel films.
Article
Chemistry, Multidisciplinary
Li Wan, De Qing Liang
Summary: Amphiphilic block copolymers (PVCap-b-PCL) containing different ratio of PCL and PVCap were synthesized and showed better performance than PVCap in methane hydrate inhibition experiments, providing longer induction time. These copolymers have potential as environmentally friendly hydrate inhibitors by adjusting the ratio of PCL to PVCap.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2021)
Article
Polymer Science
Nicoletta Inverardi, Maurizio Toselli, Giulia Scalet, Massimo Messori, Ferdinando Auricchio, Stefano Pandini
Summary: In this study, amphiphilic materials with proper shape memory effects were prepared by photo-cross-linking. These materials can cyclically change their shape between two configurations under certain thermal/mechanical conditions, showing potential applications in the biomedical field and soft robotics.
Article
Nanoscience & Nanotechnology
Peiyi Liu, Bin Wang, Yu Chen
Summary: In this study, flexible PVC films with excellent antibiofouling properties were prepared by blending amphiphilic star-shaped three-arm block copolymers with PVC and plasticizer. The resulting films exhibited outstanding hydrophilicity and stability on the surface, and maintained their antibiofouling performance even under stretching, rubbing, or bending.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Huan Qiu, Ting Shen, Zhening Yang, Feng Wu, Xiaohong Li, Yingfeng Tu, Jun Ling
Summary: Janus polymerization was utilized to synthesize multiblock copolymers with self-assembly capabilities, good shape memory properties, and potential applications in biomedical devices. The distinguishable chemical structures and thermal properties between Janus MBCPs and cationic random copolymers were confirmed, providing insights into the unique features of Janus polymerization for advanced material design and applications.
CHINESE JOURNAL OF CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Derya Burcu Hazer Rosberg, Baki Hazer, Lena Stenberg, Lars B. Dahlin
Summary: The study showed that conduits modified with gold and cobalt-oxide nanoparticles improved axonal outgrowth and decreased the number of apoptotic Schwann cells, leading to enhanced nerve regeneration after reconstruction.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Chemistry, Multidisciplinary
Radha Sachan, Sudhir G. Warkar, Roli Purwar
Summary: The shape memory properties of triblock copolymeric films were studied by synthesizing films with varying poly(epsilon-caprolactone) (PCL) chain length and constant polydimethylsiloxane (PDMS) content. The results showed that increasing the PCL chain length led to changes in the crystal morphology, thermal properties, and shape memory performance of the films. The inclusion of PDMS block affected the crystallization kinetics and shape fixity of the films.
Article
Polymer Science
Yuanyuan Dou, Han Wu, Li Zhang, Zhenbo Ning, Ni Jiang, Zhihua Gan
Summary: Three types of spherulitic morphologies, including conventional ring-banded spherulites, special spherulites with a curve-like morphology, and composite spherulites, were found in PCL-b-PA6-b-PCL due to the wide crystallization temperature range of chemically jointed PA6 blocks. The formation conditions, internal factors, and lamellar orientation and assembly of different spherulites were studied in detail. The appearance of unusual spherulitic morphology may result from different internal stress induced by chemically jointed PA6 blocks under diverse crystallization conditions.
Article
Chemistry, Multidisciplinary
Ozlem Gokce Kocabay, Osman Ismail
Summary: In this study, doxorubicin (DOX) loaded polymeric micelles (PMs) with high drug-loading encapsulation efficiency and pH-dependent drug release were successfully synthesized. The co-encapsulation of two agents led to enhanced solubility compared to DOX loaded formulations (DOX-PMs).
Article
Polymer Science
Yuandou Wang, Shuxin Wang, Wenju Hu, Feng Su, Fusheng Liu, Suming Li
Summary: Amphiphilic block copolymers were synthesized and photo-crosslinked hydrogels were prepared. The hydrogels exhibited high swelling and excellent biocompatibility. Drug loading efficiency and release rate were dependent on the hydrogel properties. Hydrogels with higher drug concentration and shorter hydrophobic block length showed higher anti-cancer activity. Therefore, these hydrogels have great potential for long-term local cancer therapy.
POLYMERS FOR ADVANCED TECHNOLOGIES
(2022)
Article
Polymer Science
Rodolfo M. de Moraes, Layde T. de Carvalho, Ana Julia R. M. Teixeira, Simone F. Medeiros, Amilton M. dos Santos
Summary: In this study, thermosensitive micelles were prepared using amphiphilic copolymers as potential candidates for drug delivery systems. The influence of PNIPAAm and PCL segmental lengths on the capacity of micelles formation was investigated. The polymers were characterized for their chemical composition, molecular weight, thermal and crystallinity properties. It was found that the critical micelle concentration (CMC) of the copolymers and the critical solution temperature (LCST) of the micelles increased with the increase in PNIPAAm segmental length, while decreased with the increase in PCL segmental length. Additionally, the size of the micelles increased with the increase of both hydrophobic and hydrophilic segments.
IRANIAN POLYMER JOURNAL
(2023)
Article
Polymer Science
Reihaneh Farajollah, Mir Mohammad Alavi Nikje, Ebrahim Saadat, Farid Abedin Dorkoosh
Summary: In this study, a novel three-dimensional waterborne polymer network containing a pentol star core was designed and synthesized. The polymer showed increased hydrophilicity, degradability, and biocompatibility compared to the core material. These results suggest that the prepared polymer has potential for biomedical applications in the future.
EUROPEAN POLYMER JOURNAL
(2021)