Review
Biochemistry & Molecular Biology
Jean Coudane, Benjamin Nottelet, Julia Mouton, Xavier Garric, Helene van den Berghe
Summary: Synthetic biopolymers are attractive alternatives to biobased polymers due to their low immune response in living organisms. This review explores the potential of grafting polymer chains onto the backbone of poly E-caprolactone (PCL) to expand its applications, with a focus on the biomedical field.
Article
Polymer Science
Leonard Ionut Atanase, Slim Salhi, Oana Cucoveica, Marijana Ponjavic, Jasmina Nikodinovic-Runic, Christelle Delaite
Summary: Biodegradable polymers have great significance in biomedical applications as they can degrade in the body, eliminating the need for retrieval or explant. This study obtained a series of PCL-b-PEA-b-PCL block copolymers with varying PCL sequence lengths, and found that the presence of the PEA central sequence has an important influence on the biodegradability of the copolymer samples.
Article
Chemistry, Applied
Aoi Nakashima, Kaho Kohori, Kazuya Yamamoto, Jun-ichi Kadokawa
Summary: Chitin hexanoate-graft-poly(epsilon-caprolactone) (ChHex-g-PCL) was found to be thermoplastic, and the thermoplasticity was confirmed by the formation of a melt-pressed film. Chitin hexanoates were prepared by hexanoylation of chitin and then the surface-initiated ring-opening graft polymerization of epsilon-caprolactone was conducted to graft PCL chains onto the hydroxy groups of chitin hexanoates. The molar substitution and degree of polymerization of the PCL graft chains were influenced by the catalyst, reaction time, and degree of substitution.
CARBOHYDRATE POLYMERS
(2022)
Editorial Material
Polymer Science
Holger Schmalz, Volker Abetz
Summary: This Special Issue presents the latest developments in synthesis, self-assembly, and potential applications of block copolymers with crystallizable blocks.
Article
Materials Science, Multidisciplinary
Evgenii A. Ksendzov, Pavel A. Nikishau, Irina M. Zurina, Viktoria S. Presniakova, Peter Timashev, Yuri A. Rochev, Svetlana Kotova, Sergei Kostjuk
Summary: A series of well-defined macromonomers and copolymers were synthesized via ROP and RAFT-mediated copolymerization, respectively. The cloud point temperature and transition temperature of the graft copolymers showed dependence on the copolymer composition. Films prepared from these copolymers displayed better cell adhesion compared to neat PNIPAM.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Chemistry, Analytical
Yawen Zhang, Xia Wang, Xiang Fang, Xianxian Yuan, Huaixia Yang, Jinming Kong
Summary: This study developed a label-free electrochemical immunoassay method for detecting CYFRA 21-1 using PCL-PEO copolymer, showing high sensitivity and specificity. The method demonstrated satisfactory results in clinical samples, indicating wide potential applications in clinical prevention and monitoring in the future.
MICROCHEMICAL JOURNAL
(2021)
Article
Polymer Science
Anna V. Kashina, Tamara K. Meleshko, Natalia N. Bogorad, Viktor K. Lavrentyev, Alexander V. Yakimansky
Summary: A novel approach to synthesizing molecular brushes with a polyimide backbone and poly(epsilon-caprolactone) side chains was developed by combining various synthesis methods, resulting in graft copolymers with relatively short PCL side chains and significant increase in molecular weight. Characterization of the obtained macroinitiators and copolymers was done using various spectroscopic techniques and their thermal properties were determined, showing that the introduction of a polyimide block did not alter the crystallinity of PCL.
Article
Materials Science, Paper & Wood
Keita Sakakibara, Hisayuki Ishida, Yuji Kinose, Yoshinobu Tsujii
Summary: In this study, novel Janus bottlebrushes with cellulose as a polymeric backbone were synthesized and self-assembled, showing microscale morphologies that have the potential to lead to the development of polymers with new morphologies and functionalities.
Article
Polymer Science
Nicoletta Inverardi, Maurizio Toselli, Giulia Scalet, Massimo Messori, Ferdinando Auricchio, Stefano Pandini
Summary: In this study, amphiphilic materials with proper shape memory effects were prepared by photo-cross-linking. These materials can cyclically change their shape between two configurations under certain thermal/mechanical conditions, showing potential applications in the biomedical field and soft robotics.
Article
Polymer Science
Eider Matxinandiarena, Agurtzane Mugica, Manuela Zubitur, Viko Ladelta, George Zapsas, Dario Cavallo, Nikos Hadjichristidis, Alejandro J. Muller
Summary: The morphology and crystallization behavior of two triblock terpolymers composed of polymethylene, equivalent to PE, PEO, and PCL were studied. The sequence of crystallization starting with the PE block, followed by the PCL block, and ending with the PEO block was determined. The tricrystalline nature of these materials was confirmed through a combination of DSC, WAXS, and PLOM experiments.
Article
Chemistry, Multidisciplinary
Radha Sachan, Sudhir G. Warkar, Roli Purwar
Summary: The shape memory properties of triblock copolymeric films were studied by synthesizing films with varying poly(epsilon-caprolactone) (PCL) chain length and constant polydimethylsiloxane (PDMS) content. The results showed that increasing the PCL chain length led to changes in the crystal morphology, thermal properties, and shape memory performance of the films. The inclusion of PDMS block affected the crystallization kinetics and shape fixity of the films.
Article
Biotechnology & Applied Microbiology
Benlin Sun, Lei Hou, Binbin Sun, Yu Han, Yunqing Zou, Juexin Huang, Yanan Zhang, Chuanliang Feng, Xiaoqiu Dou, Feng Xu
Summary: Chiral hybrid scaffolds prepared by electrospinning show potential in promoting endothelial remodeling in tissue-engineered vascular grafts, offering new insights for the treatment of cardiovascular diseases.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Polymer Science
Victor Delorme, Ghislain David, Stephane Dejean, Julia Mouton, Xavier Garric, Jean Coudane, Helene van den Berghe
Summary: Describes the synthesis of a fully biodegradable amphiphilic copolymer PCL-g-CHT, which has a hydrophobic PCL backbone and hydrophilic CHT grafts. The copolymer self-assembles into nanomicelles and can be used for novel drug delivery systems.
MACROMOLECULAR RAPID COMMUNICATIONS
(2023)
Article
Materials Science, Multidisciplinary
Teng Wang, Jiawen Zhang, Ying Cai, Lang Xu, Lingmin Yi
Summary: This study demonstrates that molecular-scale compositional heterogeneities can reduce the nonspecific interaction between proteins and surfaces, leading to improved resistance against surface contamination. The balance between hydrophilic and hydrophobic segments on the surface of the copolymer coatings provides better synergistic effects, resulting in excellent resistance to various proteins.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Polymer Science
Yuanyuan Dou, Han Wu, Li Zhang, Zhenbo Ning, Ni Jiang, Zhihua Gan
Summary: Three types of spherulitic morphologies, including conventional ring-banded spherulites, special spherulites with a curve-like morphology, and composite spherulites, were found in PCL-b-PA6-b-PCL due to the wide crystallization temperature range of chemically jointed PA6 blocks. The formation conditions, internal factors, and lamellar orientation and assembly of different spherulites were studied in detail. The appearance of unusual spherulitic morphology may result from different internal stress induced by chemically jointed PA6 blocks under diverse crystallization conditions.
