Journal
RSC ADVANCES
Volume 3, Issue 35, Pages 14975-14978Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3ra42663g
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Funding
- Fundacao para a Ciencia e a Tecnologia, (POCI)
- FEDER [SFRH/BD/31678/2006, PTDC/QUI-QUI/119823/2010, PTDC/QUI-QUI/099389/2008]
- Fundação para a Ciência e a Tecnologia [SFRH/BD/31678/2006] Funding Source: FCT
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Herein we report a new approach to the synthesis of 2,4-bifunctionalised cyclopentenones via one-pot conversion of 2-furaldehyde with morpholine followed by concomitant 1,4 addition and elimination. This protocol has also been extended to afford 2-hydroxy, 2-amino and 2-phenyl cyclopentenones.
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