Amine-functional polysiloxanes (AFPs) as efficient polymeric organocatalyst for amino catalysis: efficient multicomponent Gewald reaction, α-allylic alkylation of aldehydes, and Knoevenagel condensation

In this article, for the first time, we describe that commercially available and environmentally benign amine-functional polysiloxanes (AFPs) could be used as highly efficient metal-free amino catalysts in multicomponent Gewald reactions, alpha-allylic alkylations of aldehydes, and Knoevenagel condensations. Using catalytic amounts of AFPs, these transformations, including the Gewald reactions of ketones, sulfur, and ethyl 2-cyanoacetate, alpha-allylic alkylations of aldehydes and Knoevenagel condensations of aldehydes and the methylene-activated substrates may be carried out under mild conditions to give corresponding products in good yields.