- Home
- Publications
- Publication Search
- Publication Details
Title
Ethics of Drug Research in the Pediatric Intensive Care Unit
Authors
Keywords
Pediatric Intensive Care Unit, Drug Research, Informed Consent Process, Pediatric Intensive Care Unit Admission, Proxy Consent
Journal
PEDIATRIC DRUGS
Volume 17, Issue 1, Pages 43-53
Publisher
Springer Nature
Online
2014-10-29
DOI
10.1007/s40272-014-0101-5
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Developmental Pharmacokinetics of Piperacillin and Tazobactam Using Plasma and Dried Blood Spots from Infants
- (2014) M. Cohen-Wolkowiez et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Pediatric Microdose Study of [14C]Paracetamol to Study Drug Metabolism Using Accelerated Mass Spectrometry: Proof of Concept
- (2014) Miriam G. Mooij et al. CLINICAL PHARMACOKINETICS
- Evidence-Based Morphine Dosing for Postoperative Neonates and Infants
- (2014) Elke H. J. Krekels et al. CLINICAL PHARMACOKINETICS
- Clonidine in the sedation of mechanically ventilated children: A pilot randomized trial
- (2014) Mark Duffett et al. JOURNAL OF CRITICAL CARE
- Daily interruption of sedation in critically ill children: study protocol for a randomized controlled trial
- (2014) Nienke J Vet et al. Trials
- Multiplexed extraction and quantitative analysis of pharmaceuticals from DBS samples using digital microfluidics
- (2014) Nelson M Lafrenière et al. Bioanalysis
- The EU Paediatric Regulation: Still a Large Discrepancy Between Therapeutic Needs and Approved Paediatric Investigation Plans
- (2014) Stefan Wimmer et al. PEDIATRIC DRUGS
- Doing challenging research studies in a patient-centred way: a qualitative study to inform a randomised controlled trial in the paediatric emergency care setting
- (2014) Kerry Woolfall et al. BMJ Open
- Waiver of Informed Consent in Pediatric Resuscitation Research: A Systematic Review
- (2013) Mohamed Eltorki et al. ACADEMIC EMERGENCY MEDICINE
- Towards evidence-based dosing regimens in children on the basis of population pharmacokinetic pharmacodynamic modelling
- (2013) Rick Admiraal et al. ARCHIVES OF DISEASE IN CHILDHOOD
- How experience makes a difference: practitioners’ views on the use of deferred consent in paediatric and neonatal emergency care trials
- (2013) Kerry Woolfall et al. BMC Medical Ethics
- Current and future use of “dried blood spot” analyses in clinical chemistry
- (2013) Sylvain Lehmann et al. CLINICAL CHEMISTRY AND LABORATORY MEDICINE
- Optimal sedation in pediatric intensive care patients: a systematic review
- (2013) Nienke J. Vet et al. INTENSIVE CARE MEDICINE
- A study of consent for participation in a non-therapeutic study in the pediatric intensive care population
- (2013) Kusum Menon et al. JOURNAL OF MEDICAL ETHICS
- DNA methylome profiling using neonatal dried blood spot samples: A proof-of-principle study
- (2013) Mads Vilhelm Hollegaard et al. MOLECULAR GENETICS AND METABOLISM
- Archived neonatal dried blood spot samples can be used for accurate whole genome and exome-targeted next-generation sequencing
- (2013) Mads Vilhelm Hollegaard et al. MOLECULAR GENETICS AND METABOLISM
- An optimized hollow microneedle for minimally invasive blood extraction
- (2012) Cheng Guo Li et al. BIOMEDICAL MICRODEVICES
- Population Pharmacokinetic Analysis during the First 2 Years of Life
- (2012) Amélie Marsot et al. CLINICAL PHARMACOKINETICS
- Off-Label Drug Use in Pediatric Patients
- (2012) E Kimland et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Pharmacotherapy in Neonatal and Pediatric Extracorporeal Membrane Oxygenation (ECMO)
- (2012) E. D. Wildschut et al. CURRENT DRUG METABOLISM
- Ethical aspects of clinical research with minors
- (2012) Wendy Bos et al. EUROPEAN JOURNAL OF PEDIATRICS
- Digital microfluidics: a versatile tool for applications in chemistry, biology and medicine
- (2012) Mais J. Jebrail et al. LAB ON A CHIP
- Analog-to-digital drug screening
- (2012) Robert C. R. Wootton et al. NATURE
- Does neonatal morphine use affect neuropsychological outcomes at 8 to 9 years of age?
- (2012) Joke de Graaf et al. PAIN
- What Parents of Children Who Have Received Emergency Care Think about Deferring Consent in Randomised Trials of Emergency Treatments: Postal Survey
- (2012) Carrol Gamble et al. PLoS One
- Making Co-Enrolment Feasible for Randomised Controlled Trials in Paediatric Intensive Care
- (2012) Katie Harron et al. PLoS One
- Applications of accelerator MS in pediatric drug evaluation
- (2012) LT Vuong et al. Bioanalysis
- Application of dried blood spot sampling combined with LC-MS/MS for genotyping and phenotyping of CYP450 enzymes in healthy volunteers
- (2011) Theo Boer et al. BIOMEDICAL CHROMATOGRAPHY
- Blood sample volumes in child health research: review of safe limits
- (2011) Stephen RC Howie BULLETIN OF THE WORLD HEALTH ORGANIZATION
- The effect of inflammation on drug metabolism: a focus on pediatrics
- (2011) Nienke J. Vet et al. DRUG DISCOVERY TODAY
- Factors affecting consent in pediatric critical care research
- (2011) Kusum Menon et al. INTENSIVE CARE MEDICINE
- Consent in critical care trials: a survey of Canadian research ethics boards and critical care researchers
- (2011) Mark Duffett et al. JOURNAL OF CRITICAL CARE
- Neonatal herpes virus infection: Duration of extracorporeal support and the dose of acyclovir
- (2011) Frank Shann et al. Pediatric Critical Care Medicine
- Central extracorporeal membrane oxygenation for refractory pediatric septic shock
- (2011) Parthak Prodhan et al. Pediatric Critical Care Medicine
- Vasopressin rescue for in-pediatric intensive care unit cardiopulmonary arrest refractory to initial epinephrine dosing
- (2011) Timothy G. Carroll et al. Pediatric Critical Care Medicine
- Use of deferred consent for severely ill children in a multi-centre phase III trial
- (2011) Kathryn Maitland et al. Trials
- Protecting Participants of Clinical Trials Conducted in the Intensive Care Unit
- (2011) Brigid M. Flanagan et al. JOURNAL OF INTENSIVE CARE MEDICINE
- Pharmacokinetics of Cefotaxime and Desacetylcefotaxime in Infants during Extracorporeal Membrane Oxygenation
- (2010) M. J. Ahsman et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Parental comprehension and satisfaction in informed consent in paediatric clinical trials: a prospective study on childhood leukaemia
- (2010) H. Chappuy et al. ARCHIVES OF DISEASE IN CHILDHOOD
- Association between licence status and medication errors
- (2010) S. Conroy ARCHIVES OF DISEASE IN CHILDHOOD
- The need for noninvasive biomarkers for drug safety in neonatal circulation
- (2010) Heike Rabe Biomarkers in Medicine
- Off-label drug use in pediatric anesthesia and intensive care according to official and pediatric reference formularies
- (2010) Dermot R. Doherty et al. Canadian Journal of Anesthesia-Journal canadien d anesthesie
- Effects of Hypothermia on Pharmacokinetics and Pharmacodynamics
- (2010) Marcel P.H. van den Broek et al. CLINICAL PHARMACOKINETICS
- Paediatric investigation plans for pain: painfully slow!
- (2010) Elin H. Davies et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- The role of population PK–PD modelling in paediatric clinical research
- (2010) Roosmarijn F. W. De Cock et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- Inability to obtain deferred consent due to early death in emergency research: effect on validity of clinical trial results
- (2010) Tim C. Jansen et al. INTENSIVE CARE MEDICINE
- Clinician gate-keeping in clinical research is not ethically defensible: an analysis
- (2010) K. Sharkey et al. JOURNAL OF MEDICAL ETHICS
- Evaluation of drug formularies for pediatric intensive care
- (2010) Ilse Ceelie et al. Pediatric Critical Care Medicine
- Food and Drug Administration approval for medications used in the pediatric intensive care unit: A continuing conundrum
- (2010) Chris P. Yang et al. Pediatric Critical Care Medicine
- Effectiveness of the Informed Consent Process for a Pediatric Resuscitation Trial
- (2010) T. T. Raymond et al. PEDIATRICS
- Dried Blood Spots as a Sample Collection Technique for the Determination of Pharmacokinetics in Clinical Studies: Considerations for the Validation of a Quantitative Bioanalytical Method
- (2009) Neil Spooner et al. ANALYTICAL CHEMISTRY
- Morphine Glucuronidation in Preterm Neonates, Infants and Children Younger than 3 Years
- (2009) Catherijne A.J. Knibbe et al. CLINICAL PHARMACOKINETICS
- Pharmacokinetics and dosage adjustment in patients with renal dysfunction
- (2009) Roger K. Verbeeck et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- Parental anxiety and medical comprehension within 24 hrs of a childʼs admission to the pediatric intensive care unit*
- (2009) Jennifer S. Needle et al. Pediatric Critical Care Medicine
- Is “rescue” therapy ethical in randomized controlled trials?*
- (2009) Richard Holubkov et al. Pediatric Critical Care Medicine
- Subattomole Sensitivity in Biological Accelerator Mass Spectrometry
- (2008) Mehran Salehpour et al. ANALYTICAL CHEMISTRY
- A decade of HPLC–MS/MS in the routine clinical laboratory — Goals for further developments
- (2008) Michael Vogeser et al. CLINICAL BIOCHEMISTRY
- Pharmacokinetics and dosage adjustment in patients with hepatic dysfunction
- (2008) Roger K. Verbeeck EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now