Chronic Vitamin C Deficiency Promotes Redox Imbalance in the Brain but Does Not Alter Sodium-Dependent Vitamin C Transporter 2 Expression

Prenatal vitamin C deficiency results in differential levels of oxidative stress during late gestation in foetal guinea pig brains

(2014) Maya D. Paidi et al.   Redox Biology

Prolonged maternal vitamin C deficiency overrides preferential fetal ascorbate transport but does not influence perinatal survival in guinea pigs

(2013) Janne G. Schjoldager et al.   BRITISH JOURNAL OF NUTRITION

Regulation of Vitamin C Homeostasis during Deficiency

(2013) Maiken Lindblad et al.   Nutrients

Essential role of intracellular glutathione in controlling ascorbic acid transporter expression and function in rat hepatocytes and hepatoma cells

(2012) Lorena Mardones et al.   FREE RADICAL BIOLOGY AND MEDICINE

Dynamic expression of the sodium-vitamin C co-transporters, SVCT1 and SVCT2, during perinatal kidney development

(2012) Francisco Nualart et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Maternal Vitamin C Deficiency during Pregnancy Persistently Impairs Hippocampal Neurogenesis in Offspring of Guinea Pigs

(2012) Pernille Tveden-Nyborg et al.   PLoS One

Chronic Vitamin C Deficiency does not Accelerate Oxidative Stress in Ageing Brains of Guinea Pigs

(2011) Pernille Tveden-Nyborg et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Differential regulation of the ascorbic acid transporter SVCT2 during development and in response to ascorbic acid depletion

(2011) M. Elizabeth Meredith et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sodium-Dependent Vitamin C Transporter 2 (SVCT2) Expression and Activity in Brain Capillary Endothelial Cells after Transient Ischemia in Mice

(2011) Burkhard Gess et al.   PLoS One

Ascorbic acid depletion enhances expression of the sodium-dependent vitamin C transporters, SVCT1 and SVCT2, and uptake of ascorbic acid in livers of SMP30/GNL knockout mice

(2010) Akiko Amano et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Low ascorbic acid and increased oxidative stress in gulo(−/−) mice during development

(2010) Fiona E. Harrison et al.   BRAIN RESEARCH

Vitamin C distribution and retention in the mouse brain

(2010) Fiona E. Harrison et al.   BRAIN RESEARCH

Low vitamin C and increased oxidative stress and cell death in mice that lack the sodium-dependent vitamin C transporter SVCT2

(2010) F.E. Harrison et al.   FREE RADICAL BIOLOGY AND MEDICINE

Vitamin C deficiency in early postnatal life impairs spatial memory and reduces the number of hippocampal neurons in guinea pigs

(2009) Pernille Tveden-Nyborg et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Oxidized lipoprotein induces the macrophage ascorbate transporter (SVCT2): Protection by intracellular ascorbate against oxidant stress and apoptosis

(2009) Xiumei Chi et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Vitamin C function in the brain: vital role of the ascorbate transporter SVCT2

(2009) Fiona E. Harrison et al.   FREE RADICAL BIOLOGY AND MEDICINE

N-Glycosylation is required for Na+-dependent vitamin C transporter functionality

(2008) Veedamali S. Subramanian et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ascorbic acid protects the newborn rat brain from hypoxic-ischemia

(2008) Shinobu Miura et al.   BRAIN & DEVELOPMENT

Elevated oxidative stress and sensorimotor deficits but normal cognition in mice that cannot synthesize ascorbic acid

(2008) Fiona E. Harrison et al.   JOURNAL OF NEUROCHEMISTRY

The Na+-dependent l-ascorbic acid transporter SVCT2 expressed in brainstem cells, neurons, and neuroblastoma cells is inhibited by flavonoids

(2008) Teresa Caprile et al.   JOURNAL OF NEUROCHEMISTRY