Fat Mass and Obesity-Associated (FTO) Gene Polymorphisms Are Associated with Physical Activity, Food Intake, Eating Behaviors, Psychological Health, and Modeled Change in Body Mass Index in Overweight/Obese Caucasian Adults

Adult Onset Global Loss of the Fto Gene Alters Body Composition and Metabolism in the Mouse

(2013) Fiona McMurray et al.   PLoS Genetics

Obesity susceptibility loci and dietary intake in the Look AHEAD Trial

(2012) Jeanne M McCaffery et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

FTO expression is regulated by availability of essential amino acids

(2012) M K Cheung et al.   INTERNATIONAL JOURNAL OF OBESITY

The protective effect of the obesity-associated rs9939609 A variant in fat mass- and obesity-associated gene on depression

(2012) Z Samaan et al.   MOLECULAR PSYCHIATRY

Knockdown of the Fat Mass and Obesity Gene Disrupts Cellular Energy Balance in a Cell-Type Specific Manner

(2012) Ryan T. Pitman et al.   PLoS One

Depressive disorder moderates the effect of the FTO gene on body mass index

(2011) M Rivera et al.   MOLECULAR PSYCHIATRY

Impaired hypothalamic Fto expression in response to fasting and glucose in obese mice

(2011) N J Poritsanos et al.   Nutrition & Diabetes

Physical Activity Attenuates the Influence of FTO Variants on Obesity Risk: A Meta-Analysis of 218,166 Adults and 19,268 Children

(2011) Tuomas O. Kilpeläinen et al.   PLOS MEDICINE

Piecing together the FTO jigsaw

(2011) Timothy M Frayling et al.   GENOME BIOLOGY

FTO variant rs9939609 is associated with body mass index and waist circumference, but not with energy intake or physical activity in European- and African-American youth

(2010) Gaifen Liu et al.   BMC Medical Genetics

Crystal structure of the FTO protein reveals basis for its substrate specificity

(2010) Zhifu Han et al.   NATURE

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

(2010) Elizabeth K Speliotes et al.   NATURE GENETICS

Overexpression of Fto leads to increased food intake and results in obesity

(2010) Chris Church et al.   NATURE GENETICS

Hypothalamic-Specific Manipulation of Fto, the Ortholog of the Human Obesity Gene FTO, Affects Food Intake in Rats

(2010) Yi-Chun Loraine Tung et al.   PLoS One

The Fat Mass and Obesity Associated Gene FTO Functions in the Brain to Regulate Postnatal Growth in Mice

(2010) Xue Gao et al.   PLoS One

Where to go with FTO?

(2010) Rachel Larder et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The genetics of obesity: FTO leads the way

(2010) Katherine A. Fawcett et al.   TRENDS IN GENETICS

Genetic variants in association studies – review of strengths and weaknesses in study design and current knowledge of impact on cancer risk

(2009) Ulrika Andersson et al.   ACTA ONCOLOGICA

Dieting, restraint, and disinhibition predict women’s weight change over 6 y

(2009) Jennifer S Savage et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The FTO gene rs9939609 obesity-risk allele and loss of control over eating

(2009) Marian Tanofsky-Kraff et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Fat and carbohydrate intake modify the association between genetic variation in the FTO genotype and obesity

(2009) Emily Sonestedt et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Psychobiological traits in the risk profile for overeating and weight gain

(2009) C Davis   INTERNATIONAL JOURNAL OF OBESITY

Common genetic variation near MC4R is associated with eating behaviour patterns in European populations

(2009) F Stutzmann et al.   INTERNATIONAL JOURNAL OF OBESITY

FTO Genotype Is Associated with Body Mass Index after the Age of Seven Years But Not with Energy Intake or Leisure-Time Physical Activity

(2009) Maarit Hakanen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

“Restrained Eating” vs “Trying to Lose Weight”: How Are They Associated with Body Weight and Tendency to Overeat among Postmenopausal Women?

(2009) Candice A. Rideout et al.   JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION

Inactivation of the Fto gene protects from obesity

(2009) Julia Fischer et al.   NATURE

Risk Factors for Adult Overweight and Obesity in the Quebec Family Study: Have We Been Barking Up the Wrong Tree?

(2009) Jean-Philippe Chaput et al.   Obesity

Self-efficacy and restrained eating in relation to weight loss among overweight men and women in Turkey

(2008) Murat Bas et al.   APPETITE

Regulation of Fto/Ftm gene expression in mice and humans

(2008) George Stratigopoulos et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

FTO gene SNPs associated with extreme obesity in cases, controls and extremely discordant sister pairs

(2008) R Arlen Price et al.   BMC Medical Genetics

Genetic Variants of FTO Influence Adiposity, Insulin Sensitivity, Leptin Levels, and Resting Metabolic Rate in the Quebec Family Study

(2008) R. Do et al.   DIABETES

The Obesity Gene, FTO, Is of Ancient Origin, Up-Regulated during Food Deprivation and Expressed in Neurons of Feeding-Related Nuclei of the Brain

(2008) Robert Fredriksson et al.   ENDOCRINOLOGY

Variation in the FTO Gene Influences Food Intake but not Energy Expenditure

(2008) A. Haupt et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO

(2008) Guifang Jia et al.   FEBS LETTERS

The FTO gene and measured food intake in children

(2008) J Wardle et al.   INTERNATIONAL JOURNAL OF OBESITY

Lack of Association of Fatness-Related FTO Gene Variants with Energy Expenditure or Physical Activity

(2008) T. Berentzen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Obesity Associated Genetic Variation inFTOIs Associated with Diminished Satiety

(2008) Jane Wardle et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Genetic and Environmental Interactions in Obesity and Type 2 Diabetes

(2008) Isabela Romao et al.   JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION

An Obesity-AssociatedFTOGene Variant and Increased Energy Intake in Children

(2008) Joanne E. Cecil et al.   NEW ENGLAND JOURNAL OF MEDICINE

Polymorphisms of theFTOGene Are Associated With Variation in Energy Intake, but not Energy Expenditure

(2008) John R. Speakman et al.   Obesity

The FTO Obesity Gene. Genotyping and Gene Expression Analysis in Morbidly Obese Patients

(2008) Carina Zabena et al.   OBESITY SURGERY

Interaction between genes and lifestyle factors on obesity

(2008) Amelia Marti et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Variants in the FTO gene are associated with common obesity in the Belgian population

(2007) Armand Peeters et al.   MOLECULAR GENETICS AND METABOLISM