Optogenetics in neuroscience: what we gain from studies in mammals

Thalamic control of cortical states

(2012) James F A Poulet et al.   NATURE NEUROSCIENCE

Activation of VTA GABA Neurons Disrupts Reward Consumption

(2012) Ruud van Zessen et al.   NEURON

GABA Neurons of the VTA Drive Conditioned Place Aversion

(2012) Kelly R. Tan et al.   NEURON

Evoked Axonal Oxytocin Release in the Central Amygdala Attenuates Fear Response

(2012) H. Sophie Knobloch et al.   NEURON

Optogenetic Mimicry of the Transient Activation of Dopamine Neurons by Natural Reward Is Sufficient for Operant Reinforcement

(2012) Kyung Man Kim et al.   PLoS One

The Development and Application of Optogenetics

(2011) Lief Fenno et al.   Annual Review of Neuroscience

Dynamics of Retrieval Strategies for Remote Memories

(2011) Inbal Goshen et al.   CELL

Driving Opposing Behaviors with Ensembles of Piriform Neurons

(2011) Gloria B. Choi et al.   CELL

Optogenetic approaches to restoring visual function in retinitis pigmentosa

(2011) Volker Busskamp et al.   CURRENT OPINION IN NEUROBIOLOGY

Active Expiration Induced by Excitation of Ventral Medulla in Adult Anesthetized Rats

(2011) S. Pagliardini et al.   JOURNAL OF NEUROSCIENCE

Functional Connectome of the Striatal Medium Spiny Neuron

(2011) N. Chuhma et al.   JOURNAL OF NEUROSCIENCE

Nucleus Accumbens Medium Spiny Neurons Target Non-Dopaminergic Neurons in the Ventral Tegmental Area

(2011) Y. Xia et al.   JOURNAL OF NEUROSCIENCE

Acute Optogenetic Silencing of Orexin/Hypocretin Neurons Induces Slow-Wave Sleep in Mice

(2011) T. Tsunematsu et al.   JOURNAL OF NEUROSCIENCE

Optogenetic Interrogation of Dopaminergic Modulation of the Multiple Phases of Reward-Seeking Behavior

(2011) A. R. Adamantidis et al.   JOURNAL OF NEUROSCIENCE

A critical role for NMDA receptors in parvalbumin interneurons for gamma rhythm induction and behavior

(2011) M Carlén et al.   MOLECULAR PSYCHIATRY

Excitatory transmission from the amygdala to nucleus accumbens facilitates reward seeking

(2011) Garret D. Stuber et al.   NATURE

Functional identification of an aggression locus in the mouse hypothalamus

(2011) Dayu Lin et al.   NATURE

Reversal of cocaine-evoked synaptic potentiation resets drug-induced adaptive behaviour

(2011) Vincent Pascoli et al.   NATURE

A disinhibitory microcircuit for associative fear learning in the auditory cortex

(2011) Johannes J. Letzkus et al.   NATURE

Amygdala circuitry mediating reversible and bidirectional control of anxiety

(2011) Kay M. Tye et al.   NATURE

Hemisphere-specific optogenetic stimulation reveals left-right asymmetry of hippocampal plasticity

(2011) Michael M Kohl et al.   NATURE NEUROSCIENCE

Selective optical drive of thalamic reticular nucleus generates thalamic bursts and cortical spindles

(2011) Michael M Halassa et al.   NATURE NEUROSCIENCE

Leptin regulates the reward value of nutrient

(2011) Ana I Domingos et al.   NATURE NEUROSCIENCE

An optogenetic toolbox designed for primates

(2011) Ilka Diester et al.   NATURE NEUROSCIENCE

Timing-Dependent Septal Cholinergic Induction of Dynamic Hippocampal Synaptic Plasticity

(2011) Zhenglin Gu et al.   NEURON

Recombinase-Driver Rat Lines: Tools, Techniques, and Optogenetic Application to Dopamine-Mediated Reinforcement

(2011) Ilana B. Witten et al.   NEURON

Drug-Driven AMPA Receptor Redistribution Mimicked by Selective Dopamine Neuron Stimulation

(2011) Matthew T. C. Brown et al.   PLoS One

Functional Integration of Grafted Neural Stem Cell-Derived Dopaminergic Neurons Monitored by Optogenetics in an In Vitro Parkinson Model

(2011) Jan Tønnesen et al.   PLoS One

Optogenetic disruption of sleep continuity impairs memory consolidation

(2011) Asya Rolls et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Photostimulation of Phox2b Medullary Neurons Activates Cardiorespiratory Function in Conscious Rats

(2010) Roy Kanbar et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Molecular and Cellular Approaches for Diversifying and Extending Optogenetics

(2010) Viviana Gradinaru et al.   CELL

Multi-array silicon probes with integrated optical fibers: light-assisted perturbation and recording of local neural circuits in the behaving animal

(2010) Sébastien Royer et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Mapping brain networks in awake mice using combined optical neural control and fMRI

(2010) M. Desai et al.   JOURNAL OF NEUROPHYSIOLOGY

Dopaminergic Terminals in the Nucleus Accumbens But Not the Dorsal Striatum Corelease Glutamate

(2010) G. D. Stuber et al.   JOURNAL OF NEUROSCIENCE

Antidepressant Effect of Optogenetic Stimulation of the Medial Prefrontal Cortex

(2010) H. E. Covington et al.   JOURNAL OF NEUROSCIENCE

Global and local fMRI signals driven by neurons defined optogenetically by type and wiring

(2010) Jin Hyung Lee et al.   NATURE

Genetic dissection of an amygdala microcircuit that gates conditioned fear

(2010) Wulf Haubensak et al.   NATURE

Encoding of conditioned fear in central amygdala inhibitory circuits

(2010) Stephane Ciocchi et al.   NATURE

Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry

(2010) Alexxai V. Kravitz et al.   NATURE

Channelrhodopsin engineering and exploration of new optogenetic tools

(2010) Peter Hegemann et al.   NATURE METHODS

Tuning arousal with optogenetic modulation of locus coeruleus neurons

(2010) Matthew E Carter et al.   NATURE NEUROSCIENCE

Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures

(2010) Feng Zhang et al.   Nature Protocols

Pathway-Specific Feedforward Circuits between Thalamus and Neocortex Revealed by Selective Optical Stimulation of Axons

(2010) Scott J. Cruikshank et al.   NEURON

Single-Cell Optogenetic Excitation Drives Homeostatic Synaptic Depression

(2010) Carleton P. Goold et al.   NEURON

Two-photon single-cell optogenetic control of neuronal activity by sculpted light

(2010) B. K. Andrasfalvy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optical activation of lateral amygdala pyramidal cells instructs associative fear learning

(2010) Joshua P. Johansen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell Type-Specific Loss of BDNF Signaling Mimics Optogenetic Control of Cocaine Reward

(2010) M. K. Lobo et al.   SCIENCE

Cholinergic Interneurons Control Local Circuit Activity and Cocaine Conditioning

(2010) I. B. Witten et al.   SCIENCE

Genetic Reactivation of Cone Photoreceptors Restores Visual Responses in Retinitis Pigmentosa

(2010) V. Busskamp et al.   SCIENCE

Astrocytes Control Breathing Through pH-Dependent Release of ATP

(2010) A. V. Gourine et al.   SCIENCE

Channelrhodopsin-2 gene transduced into retinal ganglion cells restores functional vision in genetically blind rats

(2009) Hiroshi Tomita et al.   EXPERIMENTAL EYE RESEARCH

Sleep Homeostasis Modulates Hypocretin-Mediated Sleep-to-Wake Transitions

(2009) M. E. Carter et al.   JOURNAL OF NEUROSCIENCE

Photostimulation of Retrotrapezoid Nucleus Phox2b-Expressing Neurons In Vivo Produces Long-Lasting Activation of Breathing in Rats

(2009) S. B. G. Abbott et al.   JOURNAL OF NEUROSCIENCE

Ectopic Expression of Multiple Microbial Rhodopsins Restores ON and OFF Light Responses in Retinas with Photoreceptor Degeneration

(2009) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Photostimulation of channelrhodopsin-2 expressing ventrolateral medullary neurons increases sympathetic nerve activity and blood pressure in rats

(2009) Stephen B. G. Abbott et al.   JOURNAL OF PHYSIOLOGY-LONDON

Temporally precise in vivo control of intracellular signalling

(2009) Raag D. Airan et al.   NATURE

Parvalbumin neurons and gamma rhythms enhance cortical circuit performance

(2009) Vikaas S. Sohal et al.   NATURE

Driving fast-spiking cells induces gamma rhythm and controls sensory responses

(2009) Jessica A. Cardin et al.   NATURE

PINP: A New Method of Tagging Neuronal Populations for Identification during In Vivo Electrophysiological Recording

(2009) Susana Q. Lima et al.   PLoS One

Visual Properties of Transgenic Rats Harboring the Channelrhodopsin-2 Gene Regulated by the Thy-1.2 Promoter

(2009) Hiroshi Tomita et al.   PLoS One

Optogenetic control of epileptiform activity

(2009) J. Tonnesen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phasic Firing in Dopaminergic Neurons Is Sufficient for Behavioral Conditioning

(2009) H.-C. Tsai et al.   SCIENCE

Molecular Determinants Differentiating Photocurrent Properties of Two Channelrhodopsins fromChlamydomonas

(2008) Hongxia Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Light-Induced Rescue of Breathing after Spinal Cord Injury

(2008) W. J. Alilain et al.   JOURNAL OF NEUROSCIENCE

Light-activated channels targeted to ON bipolar cells restore visual function in retinal degeneration

(2008) Pamela S Lagali et al.   NATURE NEUROSCIENCE

Sparse optical microstimulation in barrel cortex drives learned behaviour in freely moving mice

(2007) Daniel Huber et al.   NATURE