The kinase ABL phosphorylates the microprocessor subunit DGCR8 to stimulate primary microRNA processing in response to DNA damage

c-Abl antagonizes the YAP oncogenic function

(2014) R Keshet et al.   CELL DEATH AND DIFFERENTIATION

MeCP2 Suppresses Nuclear MicroRNA Processing and Dendritic Growth by Regulating the DGCR8/Drosha Complex

(2014) Tian-Lin Cheng et al.   DEVELOPMENTAL CELL

The Capable ABL: What Is Its Biological Function?

(2014) J. Y. J. Wang   MOLECULAR AND CELLULAR BIOLOGY

c-Abl Stabilizes HDAC2 Levels by Tyrosine Phosphorylation Repressing Neuronal Gene Expression in Alzheimer’s Disease

(2014) Marcelo Gonzalez-Zuñiga et al.   MOLECULAR CELL

miR-34/449 miRNAs are required for motile ciliogenesis by repressing cp110

(2014) Rui Song et al.   NATURE

MicroRNA-216a inhibits pancreatic cancer by directly targeting Janus kinase 2

(2014) SILIANG WANG et al.   ONCOLOGY REPORTS

The DGCR8 RNA-Binding Heme Domain Recognizes Primary MicroRNAs by Clamping the Hairpin

(2014) Jen Quick-Cleveland et al.   Cell Reports

Beyond Secondary Structure: Primary-Sequence Determinants License Pri-miRNA Hairpins for Processing

(2013) Vincent C. Auyeung et al.   CELL

Genetic disruption of Abl nuclear import reduces renal apoptosis in a mouse model of cisplatin-induced nephrotoxicity

(2013) P Sridevi et al.   CELL DEATH AND DIFFERENTIATION

The Core Microprocessor Component DiGeorge Syndrome Critical Region 8 (DGCR8) Is a Nonspecific RNA-binding Protein

(2013) Braden M. Roth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of miR-335 upregulation on the apoptosis and invasion of lung cancer cell A549 and H1299

(2013) Huaqi Wang et al.   TUMOR BIOLOGY

c-Myc modulates microRNA processing via the transcriptional regulation of Drosha

(2013) Xingwu Wang et al.   Scientific Reports

Phosphorylation of DGCR8 Increases Its Intracellular Stability and Induces a Progrowth miRNA Profile

(2013) Kristina M. Herbert et al.   Cell Reports

The Role of γ-Secretase Activating Protein (GSAP) and Imatinib in the Regulation of γ-Secretase Activity and Amyloid-β Generation

(2012) Ishrut Hussain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-449 and MicroRNA-34b/c Function Redundantly in Murine Testes by Targeting E2F Transcription Factor-Retinoblastoma Protein (E2F-pRb) Pathway

(2012) Jianqiang Bao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biogenesis of mammalian microRNAs by a non-canonical processing pathway

(2012) Mallory A. Havens et al.   NUCLEIC ACIDS RESEARCH

Intact p53-Dependent Responses in miR-34–Deficient Mice

(2012) Carla P. Concepcion et al.   PLoS Genetics

MicroRNAs, the DNA damage response and cancer

(2011) Maikel D. Wouters et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

miRNA response to DNA damage

(2011) Guohui Wan et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

p38 MAPK/MK2-mediated induction of miR-34c following DNA damage prevents Myc-dependent DNA replication

(2010) I. G. Cannell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Posttranscriptional Crossregulation between Drosha and DGCR8

(2009) Jinju Han et al.   CELL

Modulation of microRNA processing by p53

(2009) Hiroshi I. Suzuki et al.   NATURE

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulation of non-coding RNA networks in the nervous system—What's the REST of the story?

(2009) Irfan A. Qureshi et al.   NEUROSCIENCE LETTERS

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

c-Abl Phosphorylates Hdmx and Regulates Its Interaction with p53

(2008) Valentina Zuckerman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Primary microRNA transcript retention at sites of transcription leads to enhanced microRNA production

(2008) Jan M. Pawlicki et al.   JOURNAL OF CELL BIOLOGY

Lin28 Mediates the Terminal Uridylation of let-7 Precursor MicroRNA

(2008) Inha Heo et al.   MOLECULAR CELL

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS

Primary microRNA transcripts are processed co-transcriptionally

(2008) Mariangela Morlando et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing

(2008) M. A. Newman et al.   RNA

Selective Blockade of MicroRNA Processing by Lin28

(2008) S. R. Viswanathan et al.   SCIENCE