The Role of γ-Secretase Activating Protein (GSAP) and Imatinib in the Regulation of γ-Secretase Activity and Amyloid-β Generation

γ-Secretase Catalyzes Sequential Cleavages of the AβPP Transmembrane Domain

(2017) Xuemin Xu   JOURNAL OF ALZHEIMERS DISEASE

Purification and Characterization of the Human γ-Secretase Activating Protein

(2012) Catherine L. Deatherage et al.   BIOCHEMISTRY

What the halted phase III γ-secretase inhibitor trial may (or may not) be telling us

(2011) Nina F. Schor   ANNALS OF NEUROLOGY

Nuclear signalling by membrane protein intracellular domains: The AICD enigma

(2011) Caroline Beckett et al.   CELLULAR SIGNALLING

Therapeutic intervention for Alzheimer's disease with γ-secretase inhibitors: still a viable option?

(2011) Bruno P Imbimbo et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Mercury is a direct and potent γ-secretase inhibitor affecting Notch processing and development in Drosophila

(2011) Jean-René Alattia et al.   FASEB JOURNAL

Peripheral reduction of β-amyloid is sufficient to reduce brain β-amyloid: Implications for Alzheimer's disease

(2011) J. Gregor Sutcliffe et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The projected effect of risk factor reduction on Alzheimer's disease prevalence

(2011) Deborah E Barnes et al.   LANCET NEUROLOGY

Novel γ-secretase inhibitors uncover a common nucleotide-binding site in JAK3, SIRT2, and PS1

(2010) Fang Wu et al.   FASEB JOURNAL

Gamma-secretase activating protein is a therapeutic target for Alzheimer’s disease

(2010) Gen He et al.   NATURE

TMP21 Transmembrane Domain Regulates γ-Secretase Cleavage

(2009) Raphaëlle Pardossi-Piquard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

γ-Secretase Modulation and its Promise for Alzheimers Disease: a Rationale for Drug Discovery

(2008) Dirk Beher   CURRENT TOPICS IN MEDICINAL CHEMISTRY