Article
Endocrinology & Metabolism
Yaoxuan Li, Shikai Wang, Dawen Li, Yueyue Huang, Haifang Liu, Xiaohui Zhang, Jie Qin, Xianbao Mao, Zhengda Li, Liangshi Chen, Pingpin Wei, Wen Shi, Lintao Xue
Summary: The study found that short-interval second ejaculation on the day of oocyte retrieval can significantly improve sperm quality and embryo development in oligoasthenozoospermic males receiving intracytoplasmic sperm injection (ICSI) treatment, suggesting a non-invasive and effective strategy for improving ICSI outcomes.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Reproductive Biology
Tzung-En Tsai, Pei-Hsuan Lin, Pei-Fen Lian, Chia-Jung Li, Salvatore Giovanni Vitale, Mislav Mikus, Wan-Ping Su, Hsiao-Wen Tsai, Kuan-Hao Tsui, Li-Te Lin
Summary: AOA may improve embryo quality in older patients with diminished ovarian reserve undergoing IVF-ICSI cycles, especially in women aged >= 40 years old.
JOURNAL OF OVARIAN RESEARCH
(2022)
Article
Endocrinology & Metabolism
Nan Peng, Shuiying Ma, Cheng Li, Hui Liu, Haibin Zhao, Lian-Jie Li, Qing Li, Mei Li
Summary: This study aimed to explore the clinical application value of half-ICSI treatment for infertility in assisted reproductive technology. The results showed that ICSI treatment improved laboratory results compared with IVF treatment, but there were no significant differences in clinical pregnancy and live birth rates. Therefore, the use of ICSI as an extra intervention should be judicious.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Obstetrics & Gynecology
Amanda Souza Setti, Gabriela Halpern, Daniela Paes de Almeida Ferreira Braga, Assumpto Iaconelli Jr, Edson Borges Jr
Summary: Maternal lifestyle factors, such as smoking, alcohol consumption, refined sugar, and artificial sweeteners, have a significant impact on the incidence of oocyte dimorphisms and outcomes of intracytoplasmic sperm injection (ICSI) cycles. These habits are positively associated with oocyte dimorphisms and negatively associated with ovarian stimulation response, embryo development, clinical pregnancy rates, and live birth rates. The associations are dose-dependent.
REPRODUCTIVE BIOMEDICINE ONLINE
(2022)
Review
Biochemistry & Molecular Biology
Mara Simopoulou, Anna Rapani, Sokratis Grigoriadis, Agni Pantou, Petroula Tsioulou, Evangelos Maziotis, Despina Tzanakaki, Olga Triantafyllidou, Theodoros Kalampokas, Charalampos Siristatidis, Panagiotis Bakas, Nikolaos Vlahos
Summary: The article discusses the infertility associated with endometriosis, highlighting the various pathological mechanisms that contribute to impaired reproductive dynamics. Reactive oxygen species, immune system dysregulation, and cellular architectural disruption are key mechanisms affecting oocyte and embryo development potential in endometriosis patients.
Article
Medicine, General & Internal
Houjin Dongye, Yizheng Tian, Dan Qi, Yanbo Du, Lei Yan
Summary: The influence of endometrioma on oocyte and embryo competence is inconclusive, and the benefits of surgical treatment remain uncertain. This study aimed to investigate the effect of endometrioma on oocyte and embryo quality from a morphological perspective and explore whether surgery could improve oocyte and embryo competence.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Carlotta Scarafia, Martina Masciovecchio, Stefano Canosa, Andrea Roberto Carosso, Gianluca Gennarelli, Alberto Revelli, Chiara Benedetto
Summary: The study found that in women with ovarian endometriosis, ICSI can be performed without harming oocytes or affecting the outcome. Additionally, there is no advantage in removing endometrioma before ICSI.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Obstetrics & Gynecology
Yong-Jie Lu, Qin Li, Li-Xue Chen, Tian Tian, Jia Kang, Yong-Xiu Hao, Jian-Suo Zhou, Yuan-Yuan Wang, Li-Ying Yan, Rong Li, Liang Chang, Jie Qiao
Summary: This study reveals the impact of maternal MTHFR C677T/A1298C combination polymorphisms on oocyte maturation potential and embryo quality. The findings indicate that a reduction in maternal MTHFR activity leads to a decrease in oocyte maturation potential, while women with intermediate MTHFR activity have worse embryo quality.
HUMAN REPRODUCTION OPEN
(2022)
Article
Environmental Sciences
Jingyue Chen, Yilong Miao, Qian Gao, Zhaokang Cui, Bo Xiong
Summary: The study reveals that exposure to PFOS affects the quality of oocytes by disrupting meiotic competency, cytoskeleton assembly, and mitochondrial function, leading to oxidative stress-induced apoptosis.
ENVIRONMENTAL POLLUTION
(2021)
Article
Endocrinology & Metabolism
Camille Robin, Audrey Uk, Christine Decanter, Helene Behal, Pierre Collinet, Chrystele Rubod, Anne-Laure Barbotin, Geoffroy Robin
Summary: The study aimed to evaluate the relationship between endometriosis and oocyte morphology after controlled ovarian stimulation for intracytoplasmic sperm injection (ICSI) on a large oocyte cohort, finding that endometriosis does not have a negative impact on oocytes' morphology in IVF-ICSI.
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
(2021)
Article
Reproductive Biology
Nowak Agnieszka, Kochan Joanna, Witarski Wojciech, Okolski Adam
Summary: This study aimed to assess the viability and developmental competence of equine oocytes after in vitro maturation and vitrification using the Rapid-I method. The results showed that in vitro matured oocytes vitrified in EquiproVitKit media had a high survival rate.
Article
Obstetrics & Gynecology
Xiaolei Chen, Haibin Zhao, Jiale Lv, Yi Dong, Maoning Zhao, Xinlei Sui, Ran Cui, Boyang Liu, Keliang Wu
Summary: This study investigates the efficacy of calcium (Ca2+) ionophore treatment in improving embryo development and pregnancy outcomes in patients with poor embryo development in previous intracytoplasmic sperm injection (ICSI) cycles. The results show that the use of calcium (Ca2+) ionophore significantly improves preimplantation development and pregnancy rates.
BMC PREGNANCY AND CHILDBIRTH
(2022)
Review
Endocrinology & Metabolism
Xue Wang, YaLing Xiao, ZhengYi Sun, JingRan Zhen, Qi Yu
Summary: There is no consensus on the timing intervals within ICSI cycles, leading to inconsistent and contradictory results. Further research is needed to determine the optimal time intervals for better laboratory and reproductive outcomes.
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
(2021)
Article
Endocrinology & Metabolism
Jing Ling Ruan, Shan Shan Liang, Jia Ping Pan, Zhi Qin Chen, Xiao Ming Teng
Summary: This retrospective study found that artificial oocyte activation (AOA) with calcium ionophore ionomycin can significantly improve the reproductive outcomes of patients with previous fertilization failure and poor embryo development after intracytoplasmic sperm injection (ICSI). AOA can increase fertilization rate, embryo quality, implantation rate, clinical pregnancy rate, and live birth rate, while decreasing miscarriage rate. The study suggests that AOA is an effective and safe treatment option for some infertility patients.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Xupeng Xing, Yalin Liang, Yanan Li, Yaolu Zhao, Yuxing Zhang, Zheng Li, Zicong Li, Zhenfang Wu
Summary: Fisetin, a bioactive flavonol found in fruits and vegetables, can delay the postovulatory aging of eggs, improve their development after fertilization, and inhibit the reduction of Sirt1 in aged eggs. Fisetin also increases the levels of GSH and Sod2 to reduce ROS accumulation, attenuates spindle abnormalities, mitochondrial dysfunction, and apoptosis caused by aging. Furthermore, fisetin upregulates the expression of the mitochondrial transcription factor Tfam and the mitochondrial genes Co2 and Atp8 by increasing Sirt1 in aged eggs. Finally, the anti-aging effects of fisetin are reversed by inhibiting Sirt1.