Burden of risk variants correlates with phenotype of multiple sclerosis

Multiple sclerosis genetics

(2014) Stephen Sawcer et al.   LANCET NEUROLOGY

The Refinement of Genetic Predictors of Multiple Sclerosis

(2014) Giulio Disanto et al.   PLoS One

The importance of HLA DRB1 gene allele to clinical features and disability in patients with multiple sclerosis in Lithuania

(2013) Renata Balnyte et al.   BMC Neurology

Differential effects of genetic susceptibility factors in males and females with multiple sclerosis

(2013) A. Dessa Sadovnick   CLINICAL IMMUNOLOGY

Genetic burden in multiple sclerosis families

(2013) N Isobe et al.   GENES AND IMMUNITY

Genetic burden of common variants in progressive and bout-onset multiple sclerosis

(2013) Melissa Sorosina et al.   Multiple Sclerosis Journal

Association between multiple sclerosis risk-associated SNPs and relapse and disability – a prospective cohort study

(2013) Rui Lin et al.   Multiple Sclerosis Journal

Oligoclonal bands and age at onset correlate with genetic risk score in multiple sclerosis

(2013) Hanne F Harbo et al.   Multiple Sclerosis Journal

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

(2013) Ashley H Beecham et al.   NATURE GENETICS

Risk genes associated with pediatric-onset MS but not with monophasic acquired CNS demyelination

(2013) E. D. van Pelt et al.   NEUROLOGY

Oligoclonal Band Status in Scandinavian Multiple Sclerosis Patients Is Associated with Specific Genetic Risk Alleles

(2013) Inger-Lise Mero et al.   PLoS One

Association of Genetic Markers with CSF Oligoclonal Bands in Multiple Sclerosis Patients

(2013) Maurizio A. Leone et al.   PLoS One

Multiple Sclerosis Susceptibility Genes: Associations with Relapse Severity and Recovery

(2013) Ellen M. Mowry et al.   PLoS One

Risk in complex genetics: “All models are wrong but some are useful”

(2012) Stephen Sawcer et al.   ANNALS OF NEUROLOGY

Genetic variants in the immunoglobulin heavy chain locus are associated with the IgG index in multiple sclerosis

(2012) Dorothea Buck et al.   ANNALS OF NEUROLOGY

HLA*IMP—an integrated framework for imputing classical HLA alleles from SNP genotypes

(2011) Alexander T. Dilthey et al.   BIOINFORMATICS

HLA-DRB1*15:01 and multiple sclerosis: a female association?

(2011) Haritz Irizar et al.   Multiple Sclerosis Journal

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

MHC transmission: Insights into gender bias in MS susceptibility

(2011) M. J. Chao et al.   NEUROLOGY

Aggregation of multiple sclerosis genetic risk variants in multiple and single case families

(2010) Pierre-Antoine Gourraud et al.   ANNALS OF NEUROLOGY

Heterogeneity at the HLA-DRB1 allelic variation locus does not influence multiple sclerosis disease severity, brain atrophy or cognition

(2010) Anneke Van der Walt et al.   Multiple Sclerosis Journal

Simultaneous Genotype Calling and Haplotype Phasing Improves Genotype Accuracy and Reduces False-Positive Associations for Genome-wide Association Studies

(2009) Brian L. Browning et al.   AMERICAN JOURNAL OF HUMAN GENETICS

What role for genetics in the prediction of multiple sclerosis?

(2009) Stephen Sawcer et al.   ANNALS OF NEUROLOGY

Integration of genetic risk factors into a clinical algorithm for multiple sclerosis susceptibility: a weighted genetic risk score

(2009) Philip L De Jager et al.   LANCET NEUROLOGY

The complex genetics of multiple sclerosis: pitfalls and prospects

(2008) Stephen Sawcer   BRAIN

Relapses in multiple sclerosis are age- and time-dependent

(2008) H Tremlett et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Multiple sclerosis

(2008) Alastair Compston et al.   LANCET