The cancer genome: from structure to function

Overcoming treatment resistance in acute promyelocytic leukemia and beyond

(2015) Tsz Kan Fung et al.   Oncotarget

Synonymous Mutations Frequently Act as Driver Mutations in Human Cancers

(2014) Fran Supek et al.   CELL

Pancreatic cancer genomics

(2014) David K Chang et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Next-generation Sequencing of Urologic Cancers: Next Is Now

(2014) Francisco X. Real et al.   EUROPEAN UROLOGY

Comprehensive molecular characterization of urothelial bladder carcinoma

(2014)   NATURE

Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma

(2014) Adam M Fontebasso et al.   NATURE GENETICS

Cancer Suppression by the Chromosome Custodians, BRCA1 and BRCA2

(2014) A. R. Venkitaraman   SCIENCE

TGF-beta in CAF-mediated tumor growth and metastasis

(2014) A. Calon et al.   SEMINARS IN CANCER BIOLOGY

Homeostatic control of polo-like kinase-1 engenders non-genetic heterogeneity in G2 checkpoint fidelity and timing

(2014) Hongqing Liang et al.   Nature Communications

Genome Recognition by MYC

(2014) A. Sabo et al.   Cold Spring Harbor Perspectives in Medicine

Life spanning murine gene expression profiles in relation to chronological and pathological aging in multiple organs

(2013) Martijs J. Jonker et al.   AGING CELL

The Genetics of Melanoma: Recent Advances

(2013) Victoria K. Hill et al.   Annual Review of Genomics and Human Genetics

Integrative Genomic Analyses Reveal an Androgen-Driven Somatic Alteration Landscape in Early-Onset Prostate Cancer

(2013) Joachim Weischenfeldt et al.   CANCER CELL

The Histone Demethylase PHF8 Governs Retinoic Acid Response in Acute Promyelocytic Leukemia

(2013) Maria Francisca Arteaga et al.   CANCER CELL

SnapShot: The Intestinal Crypt

(2013) Hans Clevers et al.   CELL

DNA damage leads to progressive replicative decline but extends the life span of long-lived mutant animals

(2013) H Lans et al.   CELL DEATH AND DIFFERENTIATION

Cohesin in development and disease

(2013) S. Remeseiro et al.   DEVELOPMENT

Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia

(2013) M A Dawson et al.   LEUKEMIA

Tumour heterogeneity in the clinic

(2013) Philippe L. Bedard et al.   NATURE

Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity

(2013) Austin M Dulak et al.   NATURE GENETICS

A cancer-associated BRCA2 mutation reveals masked nuclear export signals controlling localization

(2013) Anand D Jeyasekharan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Clinical value of chromosome arms 19q and 11p losses in low-grade gliomas

(2013) Agustí Alentorn et al.   NEURO-ONCOLOGY

High Preservation of CpG Cytosine Methylation Patterns at Imprinted Gene Loci in Liver and Brain of Aged Mice

(2013) Silvia Gravina et al.   PLoS One

Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma

(2013) J. J. Gartner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutational Analysis Reveals the Origin and Therapy-Driven Evolution of Recurrent Glioma

(2013) B. E. Johnson et al.   SCIENCE

Role of quantitative and qualitative characteristics of free circulating DNA in the management of patients with non-small cell lung cancer

(2013) Paola Ulivi et al.   CELLULAR ONCOLOGY

Tumour-microenvironment interactions: role of tumour stroma and proteins produced by cancer-associated fibroblasts in chemotherapy response

(2013) Matthew David Hale et al.   CELLULAR ONCOLOGY

Clinical application of circulating tumor cells in breast cancer

(2013) Leonie H. A. Broersen et al.   CELLULAR ONCOLOGY

Etiology of familial breast cancer with undetected BRCA1 and BRCA2 mutations: clinical implications

(2013) Eugenia Yiannakopoulou   CELLULAR ONCOLOGY

Dependency of Colorectal Cancer on a TGF-β-Driven Program in Stromal Cells for Metastasis Initiation

(2012) Alexandre Calon et al.   CANCER CELL

Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations

(2012) Tobias Rausch et al.   CELL

c-Myc Is a Universal Amplifier of Expressed Genes in Lymphocytes and Embryonic Stem Cells

(2012) Zuqin Nie et al.   CELL

Transcriptional Amplification in Tumor Cells with Elevated c-Myc

(2012) Charles Y. Lin et al.   CELL

The Origin and Evolution of Mutations in Acute Myeloid Leukemia

(2012) John S. Welch et al.   CELL

A unique role of cohesin-SA1 in gene regulation and development

(2012) Silvia Remeseiro et al.   EMBO JOURNAL

Self-assembly gets new direction

(2012) Matthew R. Jones et al.   NATURE

Taking a Back Door to Target Myc

(2012) G. Evan   SCIENCE

Genome Sequencing Identifies a Basis for Everolimus Sensitivity

(2012) G. Iyer et al.   SCIENCE

Interpretation of interlocking key issues of cancer stem cells in malignant solid tumors

(2012) Wei-hui Liu et al.   CELLULAR ONCOLOGY

New insights and clinical advancements in cellular oncology

(2012) Ad Geurts van Kessel   CELLULAR ONCOLOGY

Human papillomavirus-16 E5 protein: oncogenic role and therapeutic value

(2012) Niladri Ganguly   CELLULAR ONCOLOGY

Aberrant microRNA expression and its implications in the pathogenesis of leukemias

(2012) Sadegh Babashah et al.   CELLULAR ONCOLOGY

Cell culture models for studying the development of Barrett’s esophagus: a systematic review

(2012) P. Bus et al.   CELLULAR ONCOLOGY

The Origin and Nature of Tightly Clustered BTG1 Deletions in Precursor B-Cell Acute Lymphoblastic Leukemia Support a Model of Multiclonal Evolution

(2012) Esmé Waanders et al.   PLoS Genetics

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

(2011) Mark A. Dawson et al.   NATURE

Mutational Inactivation of STAG2 Causes Aneuploidy in Human Cancer

(2011) D. A. Solomon et al.   SCIENCE

Suppression of Antitumor Immunity by Stromal Cells Expressing Fibroblast Activation Protein- 

(2010) M. Kraman et al.   SCIENCE

UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit

(2009) Mathew J. Garnett et al.   NATURE CELL BIOLOGY

HP1-β mobilization promotes chromatin changes that initiate the DNA damage response

(2008) Nabieh Ayoub et al.   NATURE