The tumor suppressor geneARHI(DIRAS3)inhibits ovarian cancer cell migration through multiple mechanisms

Androgen metabolism and JAK/STAT pathway genes and prostate cancer risk

(2012) Erika M. Kwon et al.   Cancer Epidemiology

Role of α5β1 and αvβ3 integrins in relation to adhesion and spreading dynamics of prostate cancer cells interacting with fibronectin underin vitroconditions

(2012) Anna Stachurska et al.   CELL BIOLOGY INTERNATIONAL

Anticancer Properties of the IL-12 Family - Focus on Colorectal Cancer

(2012) M. A. Engel et al.   CURRENT MEDICINAL CHEMISTRY

ILK: a pseudokinase in the center stage of cell-matrix adhesion and signaling

(2012) Jun Qin et al.   CURRENT OPINION IN CELL BIOLOGY

Interleukin-6/interleukin-6 Receptor Pathway as a New Therapy Target in Epithelial Ovarian Cancer

(2012) Eveline M. Dijkgraaf et al.   CURRENT PHARMACEUTICAL DESIGN

VEGF-Induced Vascular Permeability Is Mediated by FAK

(2012) Xiao Lei Chen et al.   DEVELOPMENTAL CELL

A Conserved Lipid-binding Loop in the Kindlin FERM F1 Domain Is Required for Kindlin-mediated αIIbβ3 Integrin Coactivation

(2012) Mohamed Bouaouina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cryptococcus neoformansActivates RhoGTPase Proteins Followed by Protein Kinase C, Focal Adhesion Kinase, and Ezrin to Promote Traversal across the Blood-Brain Barrier

(2012) Jong-Chul Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N-cadherin expression level modulates integrin-mediated polarity and strongly impacts on the speed and directionality of glial cell migration

(2012) Emeline Camand et al.   JOURNAL OF CELL SCIENCE

Integrin β5 contributes to the tumorigenic potential of breast cancer cells through the Src-FAK and MEK-ERK signaling pathways

(2012) A Bianchi-Smiraglia et al.   ONCOGENE

Role of MMP-2 in the regulation of IL-6/Stat3 survival signaling via interaction with α5β1 integrin in glioma

(2012) D Kesanakurti et al.   ONCOGENE

Degradation of Internalized αvβ5 Integrin Is Controlled by uPAR Bound uPA: Effect on β1 Integrin Activity and α-SMA Stress Fiber Assembly

(2012) Lingyan Wang et al.   PLoS One

Integrin adhesions

(2012) Christine Lawson et al.   Cell Adhesion & Migration

Protein kinase G signaling disrupts Rac1-dependent focal adhesion assembly in liver specific pericytes

(2011) Chittaranjan Routray et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Integrin α6β4 cooperates with LPA signaling to stimulate Rac through AKAP-Lbc-mediated RhoA activation

(2011) Kathleen L. O'Connor et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Prognostic role of integrin β1, E-cadherin, and rac1 expression in small cell lung cancer

(2011) MYUNG HEE CHANG et al.   APMIS

RhoA GTPase regulates radiation-induced alterations in endothelial cell adhesion and migration

(2011) Matthieu Rousseau et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Combined Blockade of Integrin- 4 1 Plus Cytokines SDF-1  or IL-1  Potently Inhibits Tumor Inflammation and Growth

(2011) M. C. Schmid et al.   CANCER RESEARCH

Integrin αvβ3 promotes vitronectin gene expression in human ovarian cancer cells by implicating rel transcription factors

(2011) Ute Reuning   JOURNAL OF CELLULAR BIOCHEMISTRY

The role of mechanical stretching in the activation and localization of adhesion proteins and related intracellular molecules

(2011) F. Boccafoschi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Norepinephrine Promotes the  1-Integrin-Mediated Adhesion of MDA-MB-231 Cells to Vascular Endothelium by the Induction of a GRO  Release

(2011) C. Strell et al.   MOLECULAR CANCER RESEARCH

The tumor-suppressor gene ARHI (DIRAS3) suppresses ovarian cancer cell migration through inhibition of the Stat3 and FAK/Rho signaling pathways

(2011) D B Badgwell et al.   ONCOGENE

Endothelial Cell-Specific Molecule 2 (ECSM2) Localizes to Cell-Cell Junctions and Modulates bFGF-Directed Cell Migration via the ERK-FAK Pathway

(2011) Chunwei Shi et al.   PLoS One

Effects of Longevinex (modified resveratrol) on cardioprotection and its mechanisms of action

(2010) Subhendu Mukherjee et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

MicroRNAs 221/222 and Genistein-Mediated Regulation of ARHI Tumor Suppressor Gene in Prostate Cancer

(2010) Y. Chen et al.   Cancer Prevention Research

Kallikrein-Related Peptidase 7 Promotes Multicellular Aggregation via the α5β1Integrin Pathway and Paclitaxel Chemoresistance in Serous Epithelial Ovarian Carcinoma

(2010) Ying Dong et al.   CANCER RESEARCH

ECM-dependent mRNA expression profiles and phosphorylation patterns of p130Cas, FAK, ERK and p38 MAPK of osteoblast-like cells

(2010) Kazunori Hamamura et al.   CELL BIOLOGY INTERNATIONAL

Targeting the Urokinase Plasminogen Activator Receptor Inhibits Ovarian Cancer Metastasis

(2010) H. A. Kenny et al.   CLINICAL CANCER RESEARCH

Effects of IL-6 and AG490 on regulation of Stat3 signaling pathway and invasion of human pancreatic cancer cells in vitro

(2010) Chen Huang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Celastrol Acts as a Potent Antimetastatic Agent Targeting  1 Integrin and Inhibiting Cell-Extracellular Matrix Adhesion, in Part via the p38 Mitogen-Activated Protein Kinase Pathway

(2010) H. Zhu et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Ligand-independent activation of c-Met by fibronectin and α5β1-integrin regulates ovarian cancer invasion and metastasis

(2010) A K Mitra et al.   ONCOGENE

IL-6 augments the invasiveness of U87MG human glioblastoma multiforme cells via up-regulation of MMP-2 and fascin-1

(2010) Li   ONCOLOGY REPORTS

A prognostic gene signature in advanced ovarian cancer reveals a microfibril-associated protein (MAGP2) as a promoter of tumor cell survival and angiogenesis

(2010) Kristin Spivey et al.   Cell Adhesion & Migration

Constitutive activation of BMP signalling abrogates experimental metastasis of OVCA429 cells via reduced cell adhesion

(2010) Trevor G Shepherd et al.   Journal of Ovarian Research

Hyperphosphorylated FAK Delocalizes from Focal Adhesions to Membrane Ruffles

(2010) Abdelkader Hamadi et al.   Journal of Oncology

 1 Integrin Adhesion Enhances IL-6-Mediated STAT3 Signaling in Myeloma Cells: Implications for Microenvironment Influence on Tumor Survival and Proliferation

(2009) K. H. Shain et al.   CANCER RESEARCH

Vascular Cell Adhesion Molecule-1 Is a Regulator of Ovarian Cancer Peritoneal Metastasis

(2009) Jill K. Slack-Davis et al.   CANCER RESEARCH

α9β1 Integrin in melanoma cells can signal different adhesion states for migration and anchorage

(2009) Magnus C. Lydolph et al.   EXPERIMENTAL CELL RESEARCH

CTGF enhances migration and MMP-13 up-regulation via αvβ3 integrin, FAK, ERK, and NF-κB-dependent pathway in human chondrosarcoma cells

(2009) Tzu-Wei Tan et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Osteopontin increases migration and MMP-9 up-regulation via αvβ3 integrin, FAK, ERK, and NF-κB-dependent pathway in human chondrosarcoma cells

(2009) Ying-Ju Chen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cross talk of signals between EGFR and IL-6R through JAK2/STAT3 mediate epithelial–mesenchymal transition in ovarian carcinomas

(2008) M Colomiere et al.   BRITISH JOURNAL OF CANCER

OncogenicHRASmutations cause prolonged PI3K signaling in response to epidermal growth factor in fibroblasts of patients with Costello syndrome

(2008) Georg Rosenberger et al.   HUMAN MUTATION

Integrin αvβ3 mediates upregulation of epidermal growth-factor receptor expression and activity in human ovarian cancer cells

(2008) Daniela Lössner et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Lactate promotes glioma migration by TGF-β2–dependent regulation of matrix metalloproteinase-2

(2008) Fusun Baumann et al.   NEURO-ONCOLOGY