Role of MMP-2 in the regulation of IL-6/Stat3 survival signaling via interaction with α5β1 integrin in glioma

Inhibition of JAK1, 2/STAT3 Signaling Induces Apoptosis, Cell Cycle Arrest, and Reduces Tumor Cell Invasion in Colorectal Cancer Cells

(2015) Hua Xiong et al.   NEOPLASIA

Inhibition of nuclear factor-kappaB suppresses peritoneal dissemination of gastric cancer by blocking cancer cell adhesion

(2011) Kazuhiro Mino et al.   CANCER SCIENCE

Integrin α5β1 controls invasion of human breast carcinoma cells by direct and indirect modulation of MMP-2 collagenase activity

(2011) Galina Morozevich et al.   CELL CYCLE

JAK1 Activates STAT3 Activity in Non-Small-Cell Lung Cancer Cells and IL-6 Neutralizing Antibodies Can Suppress JAK1-STAT3 Signaling

(2011) L. Song et al.   MOLECULAR CANCER THERAPEUTICS

IL-6 promotes prostate tumorigenesis and progression through autocrine cross-activation of IGF-IR

(2011) A Rojas et al.   ONCOGENE

Suppression of MMP-2 Attenuates TNF-α Induced NF-κB Activation and Leads to JNK Mediated Cell Death in Glioma

(2011) Divya Kesanakurti et al.   PLoS One

MMP-2 siRNA Inhibits Radiation-Enhanced Invasiveness in Glioma Cells

(2011) Aruna Venkata Badiga et al.   PLoS One

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

Interleukin-6 in bone metastasis and cancer progression

(2010) Tasnim Ara et al.   EUROPEAN JOURNAL OF CANCER

Anti-interleukin-6 receptor antibody inhibits the progression in human colon carcinoma cells

(2010) Chih-Ping Hsu et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

α5β1 integrin antagonists reduce chemotherapy-induced premature senescence and facilitate apoptosis in human glioblastoma cells

(2010) Eva Martinkova et al.   INTERNATIONAL JOURNAL OF CANCER

CLP-1 associates with MyoD and HDAC to restore skeletal muscle cell regeneration

(2010) J. Galatioto et al.   JOURNAL OF CELL SCIENCE

Effects of IL-6 and AG490 on regulation of Stat3 signaling pathway and invasion of human pancreatic cancer cells in vitro

(2010) Chen Huang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Inhibition of the JAK-2/STAT3 signaling pathway impedes the migratory and invasive potential of human glioblastoma cells

(2010) Christian Senft et al.   JOURNAL OF NEURO-ONCOLOGY

siRNA-Mediated Downregulation of MMP-9 and uPAR in Combination with Radiation Induces G2/M Cell-Cycle Arrest in Medulloblastoma

(2010) P. C. N. Ganji et al.   MOLECULAR CANCER RESEARCH

Mustard NPR1, a mammalian IκB homologue inhibits NF-κB activation in human GBM cell lines

(2009) Divya Kesanakurti et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis

(2009) Julia Bollrath et al.   CANCER CELL

 1 Integrin Adhesion Enhances IL-6-Mediated STAT3 Signaling in Myeloma Cells: Implications for Microenvironment Influence on Tumor Survival and Proliferation

(2009) K. H. Shain et al.   CANCER RESEARCH

IKK/NF-κB and STAT3 pathways: central signalling hubs in inflammation-mediated tumour promotion and metastasis

(2009) Julia Bollrath et al.   EMBO REPORTS

MMP-2 alters VEGF expression via αVβ3 integrin-mediated PI3K/AKT signaling in A549 lung cancer cells

(2009) Chandramu Chetty et al.   INTERNATIONAL JOURNAL OF CANCER

N-Glycosylation of the I-like Domain of β1 Integrin Is Essential for β1 Integrin Expression and Biological Function

(2009) Tomoya Isaji et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting Interleukin 6 Signaling Suppresses Glioma Stem Cell Survival and Tumor Growth

(2009) Hui Wang et al.   STEM CELLS

Implication of α5β1 integrin in invasion of drug-resistant MCF-7/ADR breast carcinoma cells: a role for MMP-2 collagenase

(2008) G. E. Morozevich et al.   BIOCHEMISTRY-MOSCOW

An α5β1 integrin inhibitor attenuates glioma growth

(2008) Katrin Färber et al.   MOLECULAR AND CELLULAR NEUROSCIENCE