Old Yellow Enzyme-mediated reduction of β-cyano-α,β-unsaturated esters for the synthesis of chiral building blocks: stereochemical analysis of the reaction

Steric Effects on the Stereochemistry of Old Yellow Enzyme-Mediated Reductions of Unsaturated Diesters: Flipping of the Substrate within the Enzyme Active Site Induced by Structural Modifications

(2012) Elisabetta Brenna et al.   ADVANCED SYNTHESIS & CATALYSIS

Stereochemical Outcome of the Biocatalysed Reduction of Activated Tetrasubstituted Olefins by Old Yellow Enzymes 1-3

(2012) Elisabetta Brenna et al.   ADVANCED SYNTHESIS & CATALYSIS

A Three-Enzyme System Involving an Ene-Reductase for Generating Valuable Chiral Building Blocks

(2012) David Mangan et al.   ADVANCED SYNTHESIS & CATALYSIS

Structural and Catalytic Characterization of Pichia stipitis OYE 2.6, a Useful Biocatalyst for Asymmetric Alkene Reductions

(2012) Yuri A. Pompeu et al.   ADVANCED SYNTHESIS & CATALYSIS

Cascade Coupling of Ene Reductases with Alcohol Dehydrogenases: Enantioselective Reduction of Prochiral Unsaturated Aldehydes

(2012) Elisabetta Brenna et al.   ChemCatChem

Expanding the organic toolbox: a guide to integrating biocatalysis in synthesis

(2012) Christopher M. Clouthier et al.   CHEMICAL SOCIETY REVIEWS

A Substrate-Driven Approach to Determine Reactivities of α,β-Unsaturated Carboxylic Esters Towards Asymmetric Bioreduction

(2012) Gábor Tasnádi et al.   CHEMISTRY-A EUROPEAN JOURNAL

On the stereochemistry of the Baker's Yeast-mediated reduction of regioisomeric unsaturated aldehydes: Examples of enantioselectivity switch promoted by substrate-engineering

(2012) Elisabetta Brenna et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Stereo-Controlled Asymmetric Bioreduction of α,β-Dehydroamino Acid Derivatives

(2011) Clemens Stueckler et al.   ADVANCED SYNTHESIS & CATALYSIS

Productivity enhancement of CC bioreductions by coupling the in situ substrate feeding product removal technology with isolated enzymes

(2011) Elisabetta Brenna et al.   CHEMICAL COMMUNICATIONS

Biocatalytic Methods for the Synthesis of Enantioenriched Odor Active Compounds

(2011) Elisabetta Brenna et al.   CHEMICAL REVIEWS

Enantioenriched Compounds via Enzyme-Catalyzed Redox Reactions

(2011) Mélanie Hall et al.   CHEMICAL REVIEWS

Biocatalyzed Enantioselective Reduction of Activated C=C Bonds: Synthesis of Enantiomerically Enriched α-Halo-β-arylpropionic Acids

(2011) Elisabetta Brenna et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Enoate Reductase-Mediated Preparation of Methyl (S)-2-Bromobutanoate, a Useful Key Intermediate for the Synthesis of Chiral Active Pharmaceutical Ingredients

(2011) Elisabetta Brenna et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Biocatalytic Reductions of Baylis–Hillman Adducts

(2011) Adam Z. Walton et al.   ACS Catalysis

Asymmetric Synthesis of (R)-3-Hydroxy-2-methylpropanoate (‘Roche Ester’) and Derivatives via Biocatalytic CC-Bond Reduction

(2010) Clemens Stueckler et al.   ADVANCED SYNTHESIS & CATALYSIS

Biocatalytic Reductions and Chemical Versatility of the Old Yellow Enzyme Family of Flavoprotein Oxidoreductases

(2010) Helen S. Toogood et al.   ChemCatChem

Bioreduction of α-methylcinnamaldehyde derivatives: chemo-enzymatic asymmetric synthesis of Lilial™ and Helional™

(2010) Clemens Stueckler et al.   DALTON TRANSACTIONS

Stereochemical Analysis of the Enzymic Reduction of the Double Bond of α- and β-Substituted Nitrostyrenes and α-Ethoxycinnamaldehyde through Deuterium Labelling Experiments

(2010) Elisabetta Brenna et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Site-Saturation Mutagenesis of Tryptophan 116 of Saccharomyces pastorianus Old Yellow Enzyme Uncovers Stereocomplementary Variants

(2009) Santosh Kumar Padhi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A short, chemoenzymatic route to chiral β-aryl-γ-amino acids using reductases from anaerobic bacteria

(2009) Anna Fryszkowska et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Structure-Based Insight into the Asymmetric Bioreduction of the CC Double Bond of α,β-Unsaturated Nitroalkenes by Pentaerythritol Tetranitrate Reductase

(2008) Helen S. Toogood et al.   ADVANCED SYNTHESIS & CATALYSIS

Enzymatic Method for the Synthesis of Blockbuster Drug Intermediates - Synthesis of Five-Membered Cyclic γ-Amino Acid and γ-Lactam Enantiomers

(2008) Enikő Forró et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Bioreduction of Activated C=C Bonds UsingZymomonas mobilis NCR Enoate Reductase and Old Yellow Enzymes OYE 1–3 from Yeasts

(2008) Mélanie Hall et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Opposite Stereochemical Courses for Enzyme-Mediated Alkene Reductions of an Enantiomeric Substrate Pair

(2008) Despina J. Bougioukou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Organocatalytic Michael Addition of Aldehydes to Nitroethylene: Efficient Access to γ2-Amino Acids

(2008) Yonggui Chi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric bioreduction of α,β-unsaturated nitriles and ketones

(2008) Birgit Kosjek et al.   TETRAHEDRON-ASYMMETRY