Differentiation-state plasticity is a targetable resistance mechanism in basal-like breast cancer
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Title
Differentiation-state plasticity is a targetable resistance mechanism in basal-like breast cancer
Authors
Keywords
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Journal
Nature Communications
Volume 9, Issue 1, Pages -
Publisher
Springer Nature America, Inc
Online
2018-09-13
DOI
10.1038/s41467-018-05729-w
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- (2016) Maia Vinogradova et al. Nature Chemical Biology
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- (2015) Hyo-eun C Bhang et al. NATURE MEDICINE
- Multiplex single-cell profiling of chromatin accessibility by combinatorial cellular indexing
- (2015) D. A. Cusanovich et al. SCIENCE
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- (2015) Aaron Goldman et al. Nature Communications
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- (2015) Philippe Gascard et al. Nature Communications
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- (2015) Timothy J. Stuhlmiller et al. Cell Reports
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- (2013) X. Zhang et al. CANCER RESEARCH
- Developmental Fate and Cellular Maturity Encoded in Human Regulatory DNA Landscapes
- (2013) Andrew B. Stergachis et al. CELL
- Expression of GATA3 in MDA-MB-231 Triple-negative Breast Cancer Cells Induces a Growth Inhibitory Response to TGFß
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- (2013) David Lesniak et al. PLoS One
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- (2013) Anneleen Daemen et al. GENOME BIOLOGY
- Kinase Pathway Dependence in Primary Human Leukemias Determined by Rapid Inhibitor Screening
- (2012) J. W. Tyner et al. CANCER RESEARCH
- A Mammary Stem Cell Population Identified and Characterized in Late Embryogenesis Reveals Similarities to Human Breast Cancer
- (2012) Benjamin T. Spike et al. Cell Stem Cell
- Comprehensive molecular portraits of human breast tumours
- (2012) Daniel C. Koboldt et al. NATURE
- Fast gapped-read alignment with Bowtie 2
- (2012) Ben Langmead et al. NATURE METHODS
- EZH2 promotes a bi-lineage identity in basal-like breast cancer cells
- (2012) R Z Granit et al. ONCOGENE
- Correcting for cancer genome size and tumour cell content enables better estimation of copy number alterations from next-generation sequence data
- (2011) Arief Gusnanto et al. BIOINFORMATICS
- Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells
- (2011) Piyush B. Gupta et al. CELL
- Genome-wide Maps of Histone Modifications Unwind In Vivo Chromatin States of the Hair Follicle Lineage
- (2011) Wen-Hui Lien et al. Cell Stem Cell
- Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
- (2011) Brian D. Lehmann et al. JOURNAL OF CLINICAL INVESTIGATION
- Subtype and pathway specific responses to anticancer compounds in breast cancer
- (2011) L. M. Heiser et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state
- (2011) C. L. Chaffer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2010) Alexa B. Turke et al. CANCER CELL
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- (2010) Sreenath V. Sharma et al. CELL
- Comparative Epigenomic Analysis of Murine and Human Adipogenesis
- (2010) Tarjei S. Mikkelsen et al. CELL
- Epithelial-Mesenchymal Transition in Cancer: Parallels Between Normal Development and Tumor Progression
- (2010) Douglas S. Micalizzi et al. JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
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- (2010) Simon Anders et al. GENOME BIOLOGY
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- (2009) Piyush B. Gupta et al. CELL
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- (2009) Da Wei Huang et al. Nature Protocols
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- (2009) C. J. Creighton et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2008) M. Smid et al. CANCER RESEARCH
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- (2008) N. P. S. Crawford et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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