Enhancement of paclitaxel and carboplatin therapies by CCL2 blockade in ovarian cancers

A first-in-human, first-in-class, phase I study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 in patients with solid tumors

(2013) Shahneen K. Sandhu et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Twist1 Induces CCL2 and Recruits Macrophages to Promote Angiogenesis

(2013) J. M. Low-Marchelli et al.   CANCER RESEARCH

Utilizing pharmacokinetics/pharmacodynamics modeling to simultaneously examine free CCL2, total CCL2 and carlumab (CNTO 888) concentration time data

(2013) Gerald J. Fetterly et al.   JOURNAL OF CLINICAL PHARMACOLOGY

CCL2 Mediates Cross-talk between Cancer Cells and Stromal Fibroblasts That Regulates Breast Cancer Stem Cells

(2012) A. Tsuyada et al.   CANCER RESEARCH

Molecular Pathways: Regulation and Therapeutic Implications of Multidrug Resistance

(2012) K. G. Chen et al.   CLINICAL CANCER RESEARCH

Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888

(2012) Galina Obmolova et al.   MOLECULAR IMMUNOLOGY

Monocyte Chemoattractant Protein–1 Blockade Inhibits Lung Cancer Tumor Growth by Altering Macrophage Phenotype and Activating CD8+Cells

(2010) Zvi G. Fridlender et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Epithelial–mesenchymal transition in ovarian cancer

(2009) Daniele Vergara et al.   CANCER LETTERS

CC chemokine ligand 2 (CCL2) promotes prostate cancer tumorigenesis and metastasis

(2009) Jian Zhang et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Monocyte Chemoattractant Protein-1 (MCP-1): An Overview

(2009) Satish L. Deshmane et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Tissue-targeted therapy of autoimmune diabetes using dendritic cells transduced to express IL-4 in NOD mice

(2008) Rémi J. Creusot et al.   CLINICAL IMMUNOLOGY