LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival
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Title
LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival
Authors
Keywords
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Journal
Nature Communications
Volume 9, Issue 1, Pages -
Publisher
Springer Nature America, Inc
Online
2018-09-27
DOI
10.1038/s41467-018-06137-w
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Note: Only part of the references are listed.- Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
- (2017) Katrina M de Lange et al. NATURE GENETICS
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- (2016) Enis Afgan et al. NUCLEIC ACIDS RESEARCH
- Disulfide-Trapping Identifies a New, Effective Chemical Probe for Activating the Nuclear Receptor Human LRH-1 (NR5A2)
- (2016) Felipe de Jesus Cortez et al. PLoS One
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- (2016) Athanasios Stergiopoulos et al. Nature Communications
- Notch receptor regulation of intestinal stem cell homeostasis and crypt regeneration
- (2015) Alexis J. Carulli et al. DEVELOPMENTAL BIOLOGY
- Structure of Liver Receptor Homolog-1 (NR5A2) with PIP 3 hormone bound in the ligand binding pocket
- (2015) Elena P. Sablin et al. JOURNAL OF STRUCTURAL BIOLOGY
- Single-cell messenger RNA sequencing reveals rare intestinal cell types
- (2015) Dominic Grün et al. NATURE
- Silencing LRH-1 in colon cancer cell lines impairs proliferation and alters gene expression programs
- (2015) James R. Bayrer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis
- (2014) M. A. Hale et al. DEVELOPMENT
- Ex vivo culture of intestinal crypt organoids as a model system for assessing cell death induction in intestinal epithelial cells and enteropathy
- (2014) T Grabinger et al. Cell Death & Disease
- Many Inflammatory Bowel Disease Risk Loci Include Regions That Regulate Gene Expression in Immune Cells and the Intestinal Epithelium
- (2013) Michal Mokry et al. GASTROENTEROLOGY
- Nr5a2 maintains acinar cell differentiation and constrains oncogenic Kras-mediated pancreatic neoplastic initiation
- (2013) Guido von Figura et al. GUT
- Divergent Sequence Tunes Ligand Sensitivity in Phospholipid-regulated Hormone Receptors
- (2013) Paul M. Musille et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
- (2012) Luke Jostins et al. NATURE
- Antidiabetic phospholipid–nuclear receptor complex reveals the mechanism for phospholipid-driven gene regulation
- (2012) Paul M Musille et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells
- (2011) K. L. VanDussen et al. DEVELOPMENT
- Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium
- (2011) Toshiro Sato et al. GASTROENTEROLOGY
- Small Molecule Agonists of the Orphan Nuclear Receptors Steroidogenic Factor-1 (SF-1, NR5A1) and Liver Receptor Homologue-1 (LRH-1, NR5A2)
- (2011) Richard J. Whitby et al. JOURNAL OF MEDICINAL CHEMISTRY
- Colon cancer cells produce immunoregulatory glucocorticoids
- (2011) D Sidler et al. ONCOGENE
- Structural basis of coactivation of liver receptor homolog-1 by -catenin
- (2011) F. Yumoto et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
- (2009) Toshiro Sato et al. NATURE
- Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region
- (2009) Jeffrey C Barrett et al. NATURE GENETICS
- Clinical implications of mucosal healing for the management of IBD
- (2009) Guillaume Pineton de Chambrun et al. Nature Reviews Gastroenterology & Hepatology
- T cell transfer model of chronic colitis: concepts, considerations, and tricks of the trade
- (2008) Dmitry V. Ostanin et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Cell cycle-dependent regulation of extra-adrenal glucocorticoid synthesis in murine intestinal epithelial cells
- (2008) Atanas G. Atanasov et al. FASEB JOURNAL
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