Axoneme polyglutamylation regulated by Joubert syndrome protein ARL13B controls ciliary targeting of signaling molecules

Myosin-Va is required for preciliary vesicle transportation to the mother centriole during ciliogenesis

(2018) Chien-Ting Wu et al.   NATURE CELL BIOLOGY

Alterations in the balance of tubulin glycylation and glutamylation in photoreceptors leads to retinal degeneration

(2017) Montserrat Bosch Grau et al.   JOURNAL OF CELL SCIENCE

Mutations in GANAB , Encoding the Glucosidase IIα Subunit, Cause Autosomal-Dominant Polycystic Kidney and Liver Disease

(2016) Binu Porath et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Graded Control of Microtubule Severing by Tubulin Glutamylation

(2016) Max L. Valenstein et al.   CELL

Arl13b regulates Shh signaling from both inside and outside the cilium

(2016) Laura E. Mariani et al.   MOLECULAR BIOLOGY OF THE CELL

Multivalent Microtubule Recognition by Tubulin Tyrosine Ligase-like Family Glutamylases

(2015) Christopher P. Garnham et al.   CELL

Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation

(2015) Quanlong Lu et al.   NATURE CELL BIOLOGY

The Microtubule-Depolymerizing Activity of a Mitotic Kinesin Protein KIF2A Drives Primary Cilia Disassembly Coupled with Cell Proliferation

(2015) Tatsuo Miyamoto et al.   Cell Reports

FIP5 phosphorylation during mitosis regulates apical trafficking and lumenogenesis

(2014) D. Li et al.   EMBO REPORTS

The tubulin code: Molecular components, readout mechanisms, and functions

(2014) Carsten Janke   JOURNAL OF CELL BIOLOGY

Arl13b and the non-muscle myosin heavy chain IIA are required for circular dorsal ruffle formation and cell migration

(2014) C. Casalou et al.   JOURNAL OF CELL SCIENCE

Regulation of microtubule motors by tubulin isotypes and post-translational modifications

(2014) Minhajuddin Sirajuddin et al.   NATURE CELL BIOLOGY

Disruption ofTtll5/StampGene (Tubulin Tyrosine Ligase-like Protein 5/SRC-1 and TIF2-associated Modulatory Protein Gene) in Male Mice Causes Sperm Malformation and Infertility

(2013) Geun-Shik Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tubulin glycylases and glutamylases have distinct functions in stabilization and motility of ependymal cilia

(2013) Montserrat Bosch Grau et al.   JOURNAL OF CELL BIOLOGY

Rab11 proteins in health and disease

(2012) Eoin E. Kelly et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

KIF19A Is a Microtubule-Depolymerizing Kinesin for Ciliary Length Control

(2012) Shinsuke Niwa et al.   DEVELOPMENTAL CELL

SUMOylation of the small GTPase ARL-13 promotes ciliary targeting of sensory receptors

(2012) Yujie Li et al.   JOURNAL OF CELL BIOLOGY

The emerging role of Arf/Arl small GTPases in cilia and ciliopathies

(2012) Yujie Li et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Functional polycystin-1 dosage governs autosomal dominant polycystic kidney disease severity

(2012) Katharina Hopp et al.   JOURNAL OF CLINICAL INVESTIGATION

CEP41 is mutated in Joubert syndrome and is required for tubulin glutamylation at the cilium

(2012) Ji Eun Lee et al.   NATURE GENETICS

ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting

(2012) M. C. Humbert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Tubulin Deglutamylase CCPP-1 Regulates the Function and Stability of Sensory Cilia in C. elegans

(2011) Robert O'Hagan et al.   CURRENT BIOLOGY

Tubulin Tyrosine Ligase-like Genesttll3andttll6Maintain Zebrafish Cilia Structure and Motility

(2011) Narendra Pathak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interaction between FIP5 and SNX18 regulates epithelial lumen formation

(2011) Carly Willenborg et al.   JOURNAL OF CELL BIOLOGY

Post-translational regulation of the microtubule cytoskeleton: mechanisms and functions

(2011) Carsten Janke et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ciliopathies

(2011) Friedhelm Hildebrandt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Small GTPases and cilia

(2011) Yujie Li et al.   Protein & Cell

A Family of Protein-Deglutamylating Enzymes Associated with Neurodegeneration

(2010) Krzysztof Rogowski et al.   CELL

Tubulin Glutamylation Regulates Ciliary Motility by Altering Inner Dynein Arm Activity

(2010) Swati Suryavanshi et al.   CURRENT BIOLOGY

Tubulin Polyglutamylation Regulates Axonemal Motility by Modulating Activities of Inner-Arm Dyneins

(2010) Tomohiro Kubo et al.   CURRENT BIOLOGY

Identification of Tubulin Deglutamylase amongCaenorhabditis elegansand Mammalian Cytosolic Carboxypeptidases (CCPs)

(2010) Yoshishige Kimura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The small GTPases ARL-13 and ARL-3 coordinate intraflagellar transport and ciliogenesis

(2010) Yujie Li et al.   JOURNAL OF CELL BIOLOGY

Joubert syndrome Arl13b functions at ciliary membranes and stabilizes protein transport inCaenorhabditis elegans

(2010) Sebiha Cevik et al.   JOURNAL OF CELL BIOLOGY

Tubulin polyglutamylation stimulates spastin-mediated microtubule severing

(2010) Benjamin Lacroix et al.   JOURNAL OF CELL BIOLOGY

Tubulin polyglutamylation is essential for airway ciliary function through the regulation of beating asymmetry

(2010) K. Ikegami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hyperglutamylation of Tubulin Can either Stabilize or Destabilize Microtubules in the Same Cell

(2009) Dorota Wloga et al.   EUKARYOTIC CELL

A microtubule depolymerizing kinesin functions during both flagellar disassembly and flagellar assembly in Chlamydomonas

(2009) T. Piao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutations in the Cilia Gene ARL13B Lead to the Classical Form of Joubert Syndrome

(2008) Vincent Cantagrel et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Domain architecture of the atypical Arf-family GTPase Arl13b involved in cilia formation

(2008) Yuji Hori et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Rip11/Rab11-FIP5 and kinesin II complex regulates endocytic protein recycling

(2008) E. Schonteich et al.   JOURNAL OF CELL SCIENCE