Mitochondrial uncoupling reveals a novel therapeutic opportunity for p53-defective cancers
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Mitochondrial uncoupling reveals a novel therapeutic opportunity for p53-defective cancers
Authors
Keywords
-
Journal
Nature Communications
Volume 9, Issue 1, Pages -
Publisher
Springer Nature America, Inc
Online
2018-09-20
DOI
10.1038/s41467-018-05805-1
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Anthelmintic Niclosamide Disrupts the Interplay of p65 and FOXM1/β-catenin and Eradicates Leukemia Stem Cells in Chronic Myelogenous Leukemia
- (2016) Bei Jin et al. CLINICAL CANCER RESEARCH
- Deletions linked to TP53 loss drive cancer through p53-independent mechanisms
- (2016) Yu Liu et al. NATURE
- Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen
- (2016) Miao Xu et al. NATURE MEDICINE
- Niclosamide and its analogs are potent inhibitors of Wnt/β-catenin, mTOR and STAT3 signaling in ovarian cancer
- (2016) Rebecca C. Arend et al. Oncotarget
- Acetylation Is Crucial for p53-Mediated Ferroptosis and Tumor Suppression
- (2016) Shang-Jui Wang et al. Cell Reports
- Correction: A distinct p53 target gene set predicts for response to the selective p53-HDM2 inhibitor NVP-CGM097
- (2016) Sébastien Jeay et al. eLife
- 5-Lipoxygenase is a direct p53 target gene in humans
- (2015) Bianca Gilbert et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Niclosamide Analogs for Treatment of Ovarian Cancer
- (2015) Christen L. Walters Haygood et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- p53 in survival, death and metabolic health: a lifeguard with a licence to kill
- (2015) Flore Kruiswijk et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- A distinct p53 target gene set predicts for response to the selective p53–HDM2 inhibitor NVP-CGM097
- (2015) Sébastien Jeay et al. eLife
- Niclosamide ethanolamine–induced mild mitochondrial uncoupling improves diabetic symptoms in mice
- (2014) Hanlin Tao et al. NATURE MEDICINE
- Genome-wide characterization reveals complex interplay between TP53 and TP63 in response to genotoxic stress
- (2014) S. S. McDade et al. NUCLEIC ACIDS RESEARCH
- Depletion of a Putatively Druggable Class of Phosphatidylinositol Kinases Inhibits Growth of p53-Null Tumors
- (2013) Brooke M. Emerling et al. CELL
- Anticancer Effects of Niclosamide in Human Glioblastoma
- (2013) A. Wieland et al. CLINICAL CANCER RESEARCH
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Combined in silico modeling and metabolomics analysis to characterize fed-batch CHO cell culture
- (2012) Suresh Selvarasu et al. BIOTECHNOLOGY AND BIOENGINEERING
- Structure-Activity Analysis of Niclosamide Reveals Potential Role for Cytoplasmic pH in Control of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling
- (2012) Bruno D. Fonseca et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Growth Inhibition of Ovarian Tumor-Initiating Cells by Niclosamide
- (2012) Y.-T. Yo et al. MOLECULAR CANCER THERAPEUTICS
- Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells
- (2012) Oliver D. K. Maddocks et al. NATURE
- Antihelminth Compound Niclosamide Downregulates Wnt Signaling and Elicits Antitumor Responses in Tumors with Activating APC Mutations
- (2011) T. Osada et al. CANCER RESEARCH
- Niclosamide: An Established Antihelminthic Drug as a Potential Therapy Against S100A4-Mediated Metastatic Colon Tumors
- (2011) D. M. Helfman JNCI-Journal of the National Cancer Institute
- Antineoplastic Mechanisms of Niclosamide in Acute Myelogenous Leukemia Stem Cells: Inactivation of the NF- B Pathway and Generation of Reactive Oxygen Species
- (2010) Y. Jin et al. CANCER RESEARCH
- The role of mutant p53 in human cancer
- (2010) Amanda M Goh et al. JOURNAL OF PATHOLOGY
- Blinded by the Light: The Growing Complexity of p53
- (2009) Karen H. Vousden et al. CELL
- Biochemistry and Physiology of Mammalian Secreted Phospholipases A2
- (2008) Gérard Lambeau et al. Annual Review of Biochemistry
- A Phospholipid Substrate Molecule Residing in the Membrane Surface Mediates Opening of the Lid Region in Group IVA Cytosolic Phospholipase A2
- (2008) John E. Burke et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phospholipase A2structure/function, mechanism, and signaling
- (2008) John E. Burke et al. JOURNAL OF LIPID RESEARCH
- Characterization of genome-wide p53-binding sites upon stress response
- (2008) Leonie Smeenk et al. NUCLEIC ACIDS RESEARCH
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started