Cellular FRET-Biosensors to Detect Membrane Targeting Inhibitors of N-Myristoylated Proteins

Spatial partitioning improves the reliability of biochemical signaling

(2013) A. Mugler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design and Application of In Vivo FRET Biosensors to Identify Protein Prenylation and Nanoclustering Inhibitors

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A new, robust, and nonradioactive approach for exploring N-myristoylation

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Formation and Domain Partitioning of H-ras Peptide Nanoclusters: Effects of Peptide Concentration and Lipid Composition

(2012) Zhenlong Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Organization, dynamics, and segregation of Ras nanoclusters in membrane domains

(2012) L. Janosi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Plasma Membrane of Bloodstream-form African Trypanosomes Confers Susceptibility and Specificity to Killing by Hydrophobic Peptides

(2010) John M. Harrington et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N-myristoyltransferase inhibitors as new leads to treat sleeping sickness

(2010) Julie A. Frearson et al.   NATURE

Small-molecule inhibition of APT1 affects Ras localization and signaling

(2010) Frank J Dekker et al.   Nature Chemical Biology

Protein palmitoylation in neuronal development and synaptic plasticity

(2010) Yuko Fukata et al.   NATURE REVIEWS NEUROSCIENCE

Palmitoyl acyltransferase assays and inhibitors (Review)

(2009) Jeremiah M. Draper et al.   MOLECULAR MEMBRANE BIOLOGY

Nanoclusters of GPI-Anchored Proteins Are Formed by Cortical Actin-Driven Activity

(2008) Debanjan Goswami et al.   CELL

Tris (Dibenzylideneacetone) Dipalladium, a N-Myristoyltransferase-1 Inhibitor, Is Effective against Melanoma Growth In vitro and In vivo

(2008) S. S. Bhandarkar et al.   CLINICAL CANCER RESEARCH

A novel switch region regulates H-ras membrane orientation and signal output

(2008) Daniel Abankwa et al.   EMBO JOURNAL

Galectin-1 Is a Novel Structural Component and a Major Regulator of H-Ras Nanoclusters

(2008) Liron Belanis et al.   MOLECULAR BIOLOGY OF THE CELL

Inhibitors of Chronically Active Ras: Potential for Treatment of Human Malignancies

(2008) Yoel Kloog et al.   Recent Patents on Anti-Cancer Drug Discovery