The switching role of β-adrenergic receptor signalling in cell survival or death decision of cardiomyocytes

Deep RNA Sequencing Reveals Novel Cardiac Transcriptomic Signatures for Physiological and Pathological Hypertrophy

(2012) Hong Ki Song et al.   PLoS One

Attractor Landscape Analysis Reveals Feedback Loops in the p53 Network That Control the Cellular Response to DNA Damage

(2012) M. Choi et al.   Science Signaling

Cyclic AMP is both a pro-apoptotic and anti-apoptotic second messenger

(2011) P. A. Insel et al.   Acta Physiologica

β-Adrenergic receptor blockade reduces endoplasmic reticulum stress and normalizes calcium handling in a coronary embolization model of heart failure in canines

(2011) Isaac George et al.   CARDIOVASCULAR RESEARCH

Fluorescence Resonance Energy Transfer–Based Sensor Camui Provides New Insight Into Mechanisms of Calcium/Calmodulin-Dependent Protein Kinase II Activation in Intact Cardiomyocytes

(2011) Jeffrey R. Erickson et al.   CIRCULATION RESEARCH

Model-based global sensitivity analysis as applied to identification of anti-cancer drug targets and biomarkers of drug resistance in the ErbB2/3 network

(2011) Galina Lebedeva et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

A Two-Dimensional ERK-AKT Signaling Code for an NGF-Triggered Cell-Fate Decision

(2011) Jia-Yun Chen et al.   MOLECULAR CELL

Origin of bistability underlying mammalian cell cycle entry

(2011) G. Yao et al.   Molecular Systems Biology

Functional Roles of Multiple Feedback Loops in Extracellular Signal-Regulated Kinase and Wnt Signaling Pathways That Regulate Epithelial-Mesenchymal Transition

(2010) S.-Y. Shin et al.   CANCER RESEARCH

Ligand-Specific c-Fos Expression Emerges from the Spatiotemporal Control of ErbB Network Dynamics

(2010) Takashi Nakakuki et al.   CELL

β2 AR Agonists in Treatment of Chronic Heart Failure: Long Path to Translation

(2010) Mark I. Talan et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Equilibrium between Adenylyl Cyclase and Phosphodiesterase Patterns Adrenergic Agonist Dose-Dependent Spatiotemporal cAMP/Protein Kinase A Activities in Cardiomyocytes

(2010) V. De Arcangelis et al.   MOLECULAR PHARMACOLOGY

Characterization of junctate–SERCA2a interaction in murine cardiomyocyte

(2009) Soon-Jae Kwon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cell fate decisions are specified by the dynamic ERK interactome

(2009) Alex von Kriegsheim et al.   NATURE CELL BIOLOGY

The biphasic behavior of incoherent feed-forward loops in biomolecular regulatory networks

(2008) Dongsan Kim et al.   BIOESSAYS

Cardioprotective and Survival Benefits of Long-Term Combined Therapy with  2 Adrenoreceptor (AR) Agonist and  1 AR Blocker in Dilated Cardiomyopathy Postmyocardial Infarction

(2008) I. Ahmet et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Ionic Mechanisms Underlying the Positive Chronotropy Induced by β1-Adrenergic Stimulation in Guinea Pig Sinoatrial Node Cells: a Simulation Study

(2008) Yukiko Himeno et al.   Journal of Physiological Sciences

A methodology for performing global uncertainty and sensitivity analysis in systems biology

(2008) Simeone Marino et al.   JOURNAL OF THEORETICAL BIOLOGY

Simulation analysis of intracellular Na+ and Cl− homeostasis during β1-adrenergic stimulation of cardiac myocyte

(2007) Masanori Kuzumoto et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY