Attractor Landscape Analysis Reveals Feedback Loops in the p53 Network That Control the Cellular Response to DNA Damage

p53 Dynamics Control Cell Fate

(2012) J. E. Purvis et al.   SCIENCE

Recipes and mechanisms of cellular reprogramming: a case study on budding yeast Saccharomyces cerevisiae

(2011) Shengchao Ding et al.   BMC Systems Biology

A deterministic map of Waddington's epigenetic landscape for cell fate specification

(2011) Sudin Bhattacharya et al.   BMC Systems Biology

Drug discovery and assay development in the ubiquitin–proteasome system

(2010) Celia R. Berkers et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Oncogenic Wip1 Phosphatase Is Inhibited by miR-16 in the DNA Damage Signaling Pathway

(2010) X. Zhang et al.   CANCER RESEARCH

Mechanism of p53 stabilization by ATM after DNA damage

(2010) Qian Cheng et al.   CELL CYCLE

Phosphorylation and Degradation of MdmX Is Inhibited by Wip1 Phosphatase in the DNA Damage Response

(2009) X. Zhang et al.   CANCER RESEARCH

Antitumor Activity of the Selective MDM2 Antagonist Nutlin-3 Against Chemoresistant Neuroblastoma With Wild-Type p53

(2009) Tom Van Maerken et al.   JNCI-Journal of the National Cancer Institute

Boolean network-based analysis of the apoptosis network: Irreversible apoptosis and stable surviving

(2009) Zhongxing Mai et al.   JOURNAL OF THEORETICAL BIOLOGY

Cell fate decision mediated by p53 pulses

(2009) X.-P. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer attractors: A systems view of tumors from a gene network dynamics and developmental perspective

(2009) Sui Huang et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Tumor Suppressive Functions of p53

(2009) J. T. Zilfou et al.   Cold Spring Harbor Perspectives in Biology

Coherent coupling of feedback loops: a design principle of cell signaling networks

(2008) Yung-Keun Kwon et al.   BIOINFORMATICS

Explaining oscillations and variability in the p53-Mdm2 system

(2008) Carole J Proctor et al.   BMC Systems Biology

The type 2C phosphatase Wip1: An oncogenic regulator of tumor suppressor and DNA damage response pathways

(2008) Xiongbin Lu et al.   CANCER AND METASTASIS REVIEWS

PPM1D silencing by RNA interference inhibits proliferation and induces apoptosis in breast cancer cell lines with wild-type p53

(2008) Jenita Pärssinen et al.   CANCER GENETICS AND CYTOGENETICS

Structural and Functional Basis for Therapeutic Modulation of p53 Signaling

(2008) E. A. Bassett et al.   CLINICAL CANCER RESEARCH

Targeting the MDM2-p53 Interaction for Cancer Therapy

(2008) S. Shangary et al.   CLINICAL CANCER RESEARCH

Phosphorylation of MDMX Mediated by Akt Leads to Stabilization and Induces 14-3-3 Binding

(2008) Vanessa Lopez-Pajares et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oscillations and bistability in the stochastic model of p53 regulation

(2008) Krzysztof Puszyński et al.   JOURNAL OF THEORETICAL BIOLOGY

Recurrent Initiation: A Mechanism for Triggering p53 Pulses in Response to DNA Damage

(2008) Eric Batchelor et al.   MOLECULAR CELL

E2F – at the crossroads of life and death

(2008) Shirley Polager et al.   TRENDS IN CELL BIOLOGY